You Searched For: PROSCI INCORPORATED

Catalog Number: (76753-788)

Supplier: Prosci

Description: Anti-ORC6 Rabbit Polyclonal Antibody

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Catalog Number: (76751-558)

Supplier: Prosci

Description: Anti-AMHR2 Rabbit Polyclonal Antibody

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Catalog Number: (76762-378)

Supplier: Prosci

Description: Anti-PDHB Rabbit Polyclonal Antibody

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Catalog Number: (77131-348)

Supplier: Prosci

Description: Pmel-17 Peptide

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Catalog Number: (77135-024)

Supplier: Prosci

Description: PTCH Peptide

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Catalog Number: (76011-252)

Supplier: Prosci

Description: This gene encodes a kinetochore protein that functions as part of the minichromosome instability-12 centromere complex. The encoded protein is required for proper kinetochore assembly and progression through the cell cycle. Alternative splicing results in multiple transcript variants.

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Catalog Number: (76764-310)

Supplier: Prosci

Description: Anti-MED6 Rabbit Polyclonal Antibody

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Catalog Number: (76750-698)

Supplier: Prosci

Description: Anti-GJA5 Rabbit Polyclonal Antibody

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Catalog Number: (10752-186)

Supplier: Prosci

Description: TRIM21, a member of the tripartite motif (TRIM) family, is a part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. TRIM21 also acts as a cytosolic antibody receptor; detection of intracellular antibodies activate immune signaling by stimulating the transcription factor pathways of NF-kappaB, AP-1, IRF3, IRF5, and IRF7, resulting in the production of proinflammatory cytokines and the induction of an antiviral state.

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Catalog Number: (75789-750)

Supplier: Prosci

Description: Interleukin-20 Receptor Subunit alpha (IL20RA) is a single-pass type I membrane protein that is a member of the type II cytokine receptor family. IL20RA is synthetized a 553 amino acid glycoprotein precursor containing a 29 amino acid signal peptide, a 221 amino acid extracellular domain with two fibronectin type-III domains, a 24 amino acid transmembrane region, and a 279 amino acid intracellular domain. IL20RA is widely expressed with highest levels found in skin and testis and high levels in brain. IL20RA forms a heterodimer with IL20RB, and the complex serves as a receptor for IL19, IL20 and IL24. IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26.

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Catalog Number: (10075-460)

Supplier: Prosci

Description: Voltage-gated K+ channels are important determinants of neuronal membrane excitability, and differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The delayed rectifier-type (IK)channels (Kv1.5, Kv2.1, and Kv2.2) are expressed on all neuronal somata and proximal dendrites and are also found in a wide variety on non-neuronal cells types including pancreatic islets, alveolar cells and cardiac myocytes. Kv2.1 and Kv2.2 form distinct populations of K+ channels and these subunits are thought to be primarily responsible for IK in superior cervical ganglion cells.

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Catalog Number: (89416-836)

Supplier: Prosci

Description: PIG-Y Antibody: Glycosylphosphatidylinositol (GPI) lipid anchoring is an important post-translational modification of proteins that takes place in the endoplasmic reticulum. The synthesis of GPI is initiated by GPI-N-acetylglucosaminyltransferase (GPI-GnT), a complex of proteins including PIG-A, PIG-H, PIG-C, GPI1, and DPM2. PIG-Y, the mammalian homolog to yeast Eri1p, is also thought to be involved in the biosynthesis of GPI. The PIG-Y gene encodes two proteins, one of which arises from leaky scanning of the mRNA.

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Catalog Number: (10116-996)

Supplier: Prosci

Description: Polyclonal; Host: Goat; Species Reactiviy: Human; Immunogen: Frizzled 4 antibody was raised against a 13 amino acid synthetic peptide near the internal region of Frizzled 4; Application: ELISA, Western Blot

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Catalog Number: (10061-690)

Supplier: Prosci

Description: ERGIC53 peptide is used for blocking the activity of ERGIC53 antibody.

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Catalog Number: (10117-186)

Supplier: Prosci

Description: Polyclonal; Host: Goat; Species Reactiviy: Human; Immunogen: SH2D4A antibody was raised against a 13 amino acid synthetic peptide near the internal region of SH2D4A; Application: ELISA, Western Blot

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Catalog Number: (89415-472)

Supplier: Prosci

Description: Aven Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Aven is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9. It is thought that Aven functions by binding to Bcl-xL, an antiapoptotic member of the Bcl-2 family, and to Apaf-1, possibly interfering with the ability of Apaf-1 to self-associate, suggesting that Aven impedes Apaf-1-mediated caspase activation. Higher levels of Aven mRNA are seen in patients with acute leukemia than in control patients, suggesting that Aven may be useful as a prognostic indicator in leukemia patients.

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