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Supplier: Adipogen
Description: BX912 is a PDK1 (3-Phosphoinositide-dependent Kinase-1) inhibitor, with an IC(50) of 26nM.

Catalog Number: (102513-398)
Supplier: Adipogen
Description: CD4 binds to MHC Class II expressed by antigen presenting cells, facilitating T cell receptor signaling.

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Catalog Number: (102512-212)
Supplier: Adipogen
Description: Human CD30 is a member of the TNF receptor family and is expressed on mitogen activated B and T cells.

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Catalog Number: (102511-886)
Supplier: Adipogen
Description: The human CD1 genetic locus consists of five closely related genes. Three of the gene products (CD1a, CD1b and CD1c) have been officially clustered using antibodies and are expressed on cortical thymocytes, a subset of B cells, and on most professional antigen presenting cells. CD1 molecules have a specialized lipid antigen-presenting function and it is unlikely that they present conventional peptide antigens. CD1 may also be involved in costimulation.

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Catalog Number: (102512-018)
Supplier: Adipogen
Description: Human CD11b (alpha M integrin) complexes with CD18 (beta 2 integrin) to form the complement receptor type 3 (CR3) heterodimer which binds to ICAM-1, fibrinogen, C3b and coagulation factor X. CD11b expression is restricted to leukocytes, mainly to myeloid and NK cells.

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Catalog Number: (102512-168)
Supplier: Adipogen
Description: Human CD26 is a T cell activation antigen which can be associated with costimulation. The significance of the dipeptidyl peptidase IV activity remains unknown. Characterization of adenosine deaminase binding to CD26 suggests an important immunoregulatory role. Soluble CD26 serum levels are predictive for colorectal cancer.

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Catalog Number: (102988-738)
Supplier: Adipogen
Description: Anticancer compound. Shown to inhibit progression of prostate cancer cells. Anti-obesity agent. 3T3-L1 adipocyte differentiation and FAS expression inhibitor.


Supplier: Adipogen
Description: Potent and selective PYK2 inhibitor. PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796. In the functional osteogenesis assays, cultures treated with increasing concentrations of PF-4618433 starting at day 1 and maintained throughout showed a dose-dependent increases in both alkaline phosphatase activity and mineralization.

Catalog Number: (102512-382)
Supplier: Adipogen
Description: Human CD46 is a cell surface glycoprotein expressed on almost all human cells except erythrocytes. CD46 is involved with regulation of complement activation and is also a measles virus receptor.

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Supplier: Adipogen
Description: Actinomycin X2 is an anti-tumor and anti-viral antibiotic.

Catalog Number: (102514-632)
Supplier: Adipogen
Description: IL-37 (Interleukin-37) belongs to the IL-1 family. It binds to interleukin-18 receptor (IL-18R) but not to IL-1 receptor. It was shown to play an important role as a link between innate and adaptive immunity and it is suggested as a new player in the inflammatory and immune responses mediated by the IL-18/IL-18R axis. It was also shown to inhibit tumor growth.


Supplier: Adipogen
Description: Potent cell permeable and selective inhibitor of phosphatidyl-inositol 3-kinase (PI3K). Blocks class I, class II and class III PI3Ks, including some downstream targets. Blocks class I PI3K persistently and class III PI3K transiently. Induces autophagy under nutrient-rich conditions and inhibits starvation-induced autophagy due to differential effects on class I versus class III PI3 kinase. Shows some limited Vps34 preference in vitro compared to PtdIns3Kgamma. However, it is typically employed in cellular studies at a concentration of 10 mM, which can inhibit all PtdIns3Ks. Can target other kinases and affect other cellular processes, such as glycogen metabolism, lysosomal acidification, endocytosis and mitochondrial permeability transition. Anticancer compound. Neuroprotective. PKA-activation dependent lipolytic agent. Enhances ATGL-dependent hydrolysis of triacylglycerols.

Catalog Number: (102514-060)
Supplier: Adipogen
Description: ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional receptor for SARS coronavirus.


Supplier: Adipogen
Description: Antibacterial compound. Pyrimidine inhibitor of dihydrofolate reductase.

Supplier: Adipogen
Description: Monomer of aurofusarin. Mycotoxin. Anticancer and antimycobacterial compound in vivo. Moderate tyrosinase inhibitor. Anti-estrogenic.

Catalog Number: (102512-406)
Supplier: Adipogen
Description: Human CD49d molecules are integrin alpha4 chains that are expressed as heterodimers with CD29 (beta 1 integrin) or (beta 7 integrin) and function as adhesion receptors. CD49d/CD29 is mainly expressed on thymocytes and B cells with increased expression on activated T cells. The ligands for CD49d/CD29 include VCAM-1 and fibronectin.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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  • State issued document with your organization's Federal Tax ID Number
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The original product is no longer available. The replacement shown is available.
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