You Searched For: Bandelin Electronic GmbH &Co.KG

Catalog Number: (10802-446)

Supplier: Rockland Immunochemical

Description: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. A mouse DNase that causes DNA fragmentation was identified recently and designated CAD for caspase activated deoxyribonuclease. The human homologue of mouse CAD was more recently identified by three groups independently and termed CPAN, DFF40, and human CAD, respectively. DFF45/ICAD is the inhibitory protein of DFF40/CAD and forms complex with DFF40/CAD. Upon cleavage of DFF45/ICAD by activated caspase, DFF40/CAD is released and activated and eventually causes the degradation of DNA in the nuclei. Activation of DFF40/CAD, which causes DNA degradation, is the hallmark of apoptotic cell death.

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Supplier: Rockland Immunochemical

Description: Revitablot™ Western Blot Stripping Buffer

Catalog Number: (RLKCA215)

Supplier: Rockland Immunochemical

Description: Green Fluorescent Protein (GFP) Chemiluminescent Western Blot Kit

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Catalog Number: (RL100-401-A25)

Supplier: Rockland Immunochemical

Description: Cancer, Cell Signaling Primary Antibody Anti-HIF1 alpha P564 [Rb] functional in Western Blot, ELISA & IP reactivity to Human, Mouse, Rat. Rockland Immunochemicals can also Custom Produce Antibodies for your Research

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Catalog Number: (RL101-1104)

Supplier: Rockland Immunochemical

Description: Secondary Goat Anti-IgG F(ab')2 Reacts with Cow (Bovine, Cattle)

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Catalog Number: (RL2004333S)

Supplier: Rockland Immunochemical

Description: Anti-Ovalbumin (Hen Egg White) (Rabbit) Antibody Peroxidase Conjugated Is Suitable For Western Blotting, ELISA, Ihc And Ip. Researchers Should Determine Optimal Titers For Applications That Are Not Stated Below.

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Catalog Number: (RL200301379)

Supplier: Rockland Immunochemical

Description: Anti-RFP antibodies is designed to detect Red Fluorescent Protein and its variants. This antibody can be used to detect RFP by ELISA (sandwich or capture) for the direct binding of antigen. Biotin conjugated anti-RFP used in a sandwich ELISA with unconjugated.

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Catalog Number: (10800-130)

Supplier: Rockland Immunochemical

Description: Ataxin-1 is a member of the ATXN1 protein family and contains a single AXH domain. It is a neurodegenerative disorder protein thought to have a role in the metabolism of RNA as it has been shown to localize to the RNA and transcription dependent inclusions within the nucleus. A mutation of Ataxin-1 is the cause of spinocerebellar ataxia type-1 (SCA1), a progressive, neurodegenerative disease that is autosomal dominant and primarily affects the Purjinke cells found in brain stem neuronal populations and the cerebellum. Expression of Ataxin-1 is almost ubiquitous, except in the brain where it is isolated to populations of neurons. Anti-Ataxin-1 is ideal for research in Neuroscience.

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Catalog Number: (10799-912)

Supplier: Rockland Immunochemical

Description: Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins. This antibody is suitable for researchers interested in cancer and stem cell research.

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Catalog Number: (10800-084)

Supplier: Rockland Immunochemical

Description: Accumulation of the amyloid-beta peptide (Abeta) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. The beta-amyloid protein precursor (APP) is cleaved by one of two beta-secretases (BACE and BACE2), producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for gamma-secretase to generate the 4 kDa amyloid-beta peptide (Abeta), which is deposited in the Alzheimer's disease patient's brains. Recently, Death Receptor 6 (DR6) was found to interact with an amino-terminal fragment of the beta-amyloid protein (N-APP) in neurons, activating a caspase 6-dependent apoptotic event leading to axonal degeneration and pruning during development, suggesting that these two proteins are involved in neural development and may possibly play a role in Alzheimer's disease.

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Catalog Number: (RL201032080100)

Supplier: Rockland Immunochemical

Description: Plasminogen [Human Plasma] in a standard capture ELISA using ABTS as a substrate for 30 minutes at room temperature

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Catalog Number: (RL600-401-B05S)

Supplier: Rockland Immunochemical

Description: antibody has been tested for use in ELISA and western blotting using recombinant Nedd4 protein. 25ul Related Product Western Blotting Kit RLKCA003

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Catalog Number: (RL600401I87)

Supplier: Rockland Immunochemical

Description: Anti-Histone H3 [Dimethyl Lys36] antibody is useful for Western Blot, Chromatin Immunoprecipitation, Dot Blot, and Immunocytochemistry/Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately

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Supplier: Rockland Immunochemical

Description: Recombinant Human LIF control protein

Catalog Number: (10800-706)

Supplier: Rockland Immunochemical

Description: CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family, a group of cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a cell surface glycoprotein that associates with integrins and appears to promote muscle cell fusion and support myotube maintenance. Along with SCARB1, LDL-R, and CLDN1, CD81 has been reported to be an entry factor for the Hepatitis C virus. Finally, recent evidence indicates that the CD81 gene is localized in a tumor-suppressor gene region and is thus a candidate gene for malignancies.

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Catalog Number: (10803-024)

Supplier: Rockland Immunochemical

Description: DYRK1A is a member of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family and is thought to be involved in neuronal differentiation, neurodegenerative diseases, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. DYRK1A phosphorylates several transcription factors such as p53, leading to inhibition of embryonic neuronal cell proliferation. DYRK1A associates with multiple proteins, including SPRED1 and SPRED2; this association appears to inhibit the phosphorylation activity of DYRK1A. Recent evidence also suggests that DYRK1A may be involved in the replication of HIV-1.

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