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Catalog Number: (103265-642)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgG Fd-HRP antibody for use in ELISA assays.


Catalog Number: (101442-504)
Supplier: Southern Biotechnology
Description: Mouse IgG2a-PE/Texas Red for use as a control in flow cytometry assays.


Catalog Number: (100243-304)
Supplier: Southern Biotechnology
Description: CD22, also known as Lyb-8, is a heterodimeric transmembrane glycoprotein and a member of a structurally related group of immunoglobulin (Ig) superfamily domain-containing proteins called the sialoadhesin family. It is detected in the cytoplasm early in B cell development (late pro-B cell stage), appears on the cell surface concomitant with IgD, and is found on most IgM+IgD+ mature B lymphocytes. Expression is lost with terminal differentiation of B cells and is absent on plasma cells. Activation of B cells via cross-linking of surface Ig increases CD22 expression. CD22 associates with the B cell receptor (BCR) complex and mediates intercellular adhesion. Its intracellular domain is phosphorylated after antigen receptor cross-linking and is involved in negative regulation of B cell activation.


Catalog Number: (100244-046)
Supplier: Southern Biotechnology
Description: Ly-6G/Ly-6C, formerly known as the myeloid differentiation antigen Gr-1, is a GPI-anchored protein. In the bone marrow, the level of antigen expression is directly correlated with granulocyte differentiation and maturation. It is also transiently expressed on monocytes in the bone marrow. In the periphery, Ly-6G/Ly-6C is expressed predominantly on neutrophils.


Catalog Number: (103264-730)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgG(H+L)-HRP antibody with minimal reactivity to mouse, bovine, and horse serum proteins for use in ELISA assays.


Catalog Number: (103265-640)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgG Fd-AP antibody for use in ELISA assays.


Catalog Number: (100242-114)
Supplier: Southern Biotechnology
Description: Rat IgG2b-CY5 for use as a control in flow cytometry and immunohistochemistry assays.


Catalog Number: (100243-522)
Supplier: Southern Biotechnology
Description: CD45R, also known as B220, a member of the protein tyrosine phosphate family and a major cell surface glycoprotein, represents a restricted form of the CD45 family which primarily recognizes only cells of B-lineage from pro-B cell through mature B lymphocytes and prior to the availability of anti-CD19 monoclonal antibodies was commonly used as a pan B-cell marker. It also reacts with certain activated T cells as well as non-MHC-restricted lytically active lymphokine-activated killer (LAK) cells. In vivo administration of RA3-6B2 has been shown to affect differentiation of both T and B cells in normal mice and reduce the level of anti-DNA antibodies and lymphadenopathies in MRL/lpr mice.


Catalog Number: (100245-072)
Supplier: Southern Biotechnology
Description: Purified Rabbit F(ab')2 Anti-Mouse IgG(H+L) antibody with minimal reactivity to human proteins for use in ELISA, flow cytometry, and immunohistochemistry assays.


Catalog Number: (100243-872)
Supplier: Southern Biotechnology
Description: The monoclonal antibody DX5 reacts with CD49b, also known as very late antigen-2 (VLA-2) and α2 integrin. The antibody stains the majority of NK cells and a small subpopulation of T cells in all mouse strains tested (e.g., A/J, AKR, BALB/c, C3H/HeJ, C57BL/6, C57BL/10, C57BR, C58, CBA/Ca, CBA/J, DBA/1, DBA/2, SJL, SWR). Three-color flow cytometry analysis has revealed that most cells that express NK-1.1 (NKR-P1C) also express CD49b. However, small subsets of DX5+NK-1.1- and DX5-NK-1.1+ cells can be found, especially among the CD3+ population of T lymphocytes. NK cells cultured in the presence of IL-2 progressively lose reactivity with DX5 as a consequence of cellular proliferation. Therefore, DX5 can be used to define functionally distinct subsets of murine NK cells. The monoclonal antibody DX5 has not been demonstrated to have activating or blocking activity.


Catalog Number: (100243-432)
Supplier: Southern Biotechnology
Description: The lymphocyte Fcγ receptors recognize the Fc portion of IgG, presented either as immune complexes or as free antibody. The different classes of receptors are distinct because of varying size, tissue distribution and affinity for IgGs. The Fc type II receptor is expressed on a wide variety of cells including B cells, hematopoietic cells, monocyte/macrophages, neutrophils, platelets, Langerhans cells, eosinophils, basophils, trophoblasts, and endothelial cells of the placenta. The Fcγ type III receptors are higher affinity than the type II and are expressed on macrophages, NK cells and neutrophils. Both types of receptors can be expressed on the same cell and in varying ratios. The receptors are constitutively expressed, although cytokines and lymphokines can modulate their expression. Besides identifying FcγR+ cells, monoclonal antibodies to the FcγII/III receptor have been used to block Fc receptor binding of IgG, Fc-mediated signal transduction and effector functions, clearance of immune complexes and to attenuate infection by organisms dependent on FcγR for parasitic invasion. The monoclonal antibody 93 recognizes a conformational epitope formed by FcγII and FcγIII receptors.


Catalog Number: (100245-056)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Turkey IgY(H+L) antibody for use in ELISA, immunohistochemistry, and western blotting assays.


Catalog Number: (100244-066)
Supplier: Southern Biotechnology
Description: Ly-6G/Ly-6C, formerly known as the myeloid differentiation antigen Gr-1, is a GPI-anchored protein. In the bone marrow, the level of antigen expression is directly correlated with granulocyte differentiation and maturation. It is also transiently expressed on monocytes in the bone marrow. In the periphery, Ly-6G/Ly-6C is expressed predominantly on neutrophils.


Catalog Number: (100245-776)
Supplier: Southern Biotechnology
Description: PE Anti-Human IgA2 antibody for use in flow cytometry and multiplex assays.


Supplier: Southern Biotechnology
Description: PE Anti-Mouse IgG2a antibody for use in flow cytometry assays.

Catalog Number: (103264-404)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG(H+L)-FITC antibody for use in fluorescent assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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