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Catalog Number: (100243-092)
Supplier: Southern Biotechnology
Description: CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The monoclonal antibody C363.29B recognizes an epitope on the 25 kDa ε chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble C363.29B can activate primed and naïve T cell in vitro. Immobilized C363.2B9 monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. The monoclonal antibody is cytolytic, easily used for cell surface staining, and a good immunoprecipitating antibody.


Catalog Number: (103259-822)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG2b-HRP antibody with minimal reactivity to human, bovine, and horse serum proteins for use in ELISA, western blotting, and immunocytochemistry assays.


Catalog Number: (100242-460)
Supplier: Southern Biotechnology
Description: Purified Anti-Mouse TNF-alpha antibody for use in flow cytometry, immunohistochemistry, western blotting, ELISA, and ELISpot assays.


Supplier: Southern Biotechnology
Description: The monoclonal antibody 5H10.27 reacts with the α5 chain (VLA-5) of the CD49e/CD29 heterodimeric fibronectin receptor. It is expressed on thymocytes, activated T cells, mast cells, and a variety of mouse cell lines. Soluble 5H10.27 antibody inhibits VLA-5-mediated functions in vitro. Immobilized 5H10.27 has also been demonstrated to costimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3 monoclonal antibody.

Catalog Number: (103265-694)
Supplier: Southern Biotechnology
Description: CD11a, also known as leukocyte function-associated antigen-1 (LFA-1α), represents the 180 kDa integrin αL subunit which combines with the CD18 β2 integrin subunit to form the αLβ2 integrin heterodimer. It is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T cells. CD11a mediates adhesion of lymphocytes to vascular endothelium and is involved in costimulation.


Catalog Number: (100242-094)
Supplier: Southern Biotechnology
Description: Low Endotoxin/Azide Free Rat IgG2a for use as a control in flow cytometry, immunohistochemistry, immunoprecipitation, and in vivo / in vitro assays and as a standard in ELISA.


Catalog Number: (100242-414)
Supplier: Southern Biotechnology
Description: Biotin Anti-Mouse IL-10 antibody for use in flow cytometry, immunohistochemistry, ELISA, western blotting, and immunoprecipitation assays.


Catalog Number: (100242-074)
Supplier: Southern Biotechnology
Description: Rat IgG1-APC for use as a control in flow cytometry assays.


Catalog Number: (103264-996)
Supplier: Southern Biotechnology
Description: Biotin Anti-Goat IgG Fc antibody for use in ELISA, immunohistochemistry, and western blotting assays.


Catalog Number: (100243-582)
Supplier: Southern Biotechnology
Description: CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes, and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN γ, IL-1, TNF-α, lipopolysaccharide, and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1.


Catalog Number: (103259-792)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Mouse IgG2a antibody with minimal reactivity to human, bovine, and horse serum proteins for use in ELISA assays.


Catalog Number: (100242-436)
Supplier: Southern Biotechnology
Description: Biotin Anti-Mouse IL-10 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, ELISA, and ELISpot assays.


Catalog Number: (100246-302)
Supplier: Southern Biotechnology
Description: CD49f is the 125 kDa integrin α6 chain which associates noncovalently with the integrin β1 subunit (CD29) and with the integrin β4 (CD104) chain to form, respectively, the very late antigen-6 (VLA-6) and α6β4 integrin heterodimers. VLA-6 is expressed on thymocytes, T lymphocytes, monocytes, and platelets. CD49f/CD29 expression is upregulated on activated T lymphocytes and memory T cells. VLA-6 serves as the laminin receptor on platelets, monocytes, and T cells. VLA-6-mediated binding to laminin provides a costimulatory signal to T cells for activation and proliferation.


Catalog Number: (103265-276)
Supplier: Southern Biotechnology
Description: CD61 is the integrin β3 subunit, a 110 kDa transmembrane glycoprotein expressed on platelets, megakaryocytes, and endothelial cells. Integrin β3 associates with gpIIb (CD41) to form the CD41/CD61 complex that mediates platelet adhesion and aggregation. CD61 also associates with CD51 to form the αVβ3 vitronectin receptor.


Catalog Number: (100245-714)
Supplier: Southern Biotechnology
Description: AP Anti-Human IgG1 Hinge antibody for use in ELISA, immunohistochemistry, and western blotting assays.


Catalog Number: (101190-238)
Supplier: Southern Biotechnology
Description: Low Endotoxin/Azide Free Anti-Mouse TNF-alpha antibody for use in flow cytometry, immunohistochemistry, western blotting, ELISA, ELISpot, and neutralization assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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