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Catalog Number: (100245-078)
Supplier: Southern Biotechnology
Description: Rabbit F(ab')2 Anti-Mouse IgG(H+L)-HRP antibody with minimal reactivity to human proteins for use in ELISA and immunohistochemistry assays.


Catalog Number: (103265-670)
Supplier: Southern Biotechnology
Description: Alexa Fluor 647 Anti-Chicken IgM antibody for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.


Catalog Number: (100245-056)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Turkey IgY(H+L) antibody for use in ELISA, immunohistochemistry, and western blotting assays.


Catalog Number: (100243-084)
Supplier: Southern Biotechnology
Description: CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3ε is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. 500-A2 recognizes an epitope on the 25 kDa ε chain of the CD3/TCR complex of mouse strains tested.


Catalog Number: (100245-658)
Supplier: Southern Biotechnology
Description: HRP Anti-Human IgM antibody for use in ELISA and western blotting assays.


Catalog Number: (100244-066)
Supplier: Southern Biotechnology
Description: Ly-6G/Ly-6C, formerly known as the myeloid differentiation antigen Gr-1, is a GPI-anchored protein. In the bone marrow, the level of antigen expression is directly correlated with granulocyte differentiation and maturation. It is also transiently expressed on monocytes in the bone marrow. In the periphery, Ly-6G/Ly-6C is expressed predominantly on neutrophils.


Catalog Number: (100243-432)
Supplier: Southern Biotechnology
Description: The lymphocyte Fcγ receptors recognize the Fc portion of IgG, presented either as immune complexes or as free antibody. The different classes of receptors are distinct because of varying size, tissue distribution and affinity for IgGs. The Fc type II receptor is expressed on a wide variety of cells including B cells, hematopoietic cells, monocyte/macrophages, neutrophils, platelets, Langerhans cells, eosinophils, basophils, trophoblasts, and endothelial cells of the placenta. The Fcγ type III receptors are higher affinity than the type II and are expressed on macrophages, NK cells and neutrophils. Both types of receptors can be expressed on the same cell and in varying ratios. The receptors are constitutively expressed, although cytokines and lymphokines can modulate their expression. Besides identifying FcγR+ cells, monoclonal antibodies to the FcγII/III receptor have been used to block Fc receptor binding of IgG, Fc-mediated signal transduction and effector functions, clearance of immune complexes and to attenuate infection by organisms dependent on FcγR for parasitic invasion. The monoclonal antibody 93 recognizes a conformational epitope formed by FcγII and FcγIII receptors.


Catalog Number: (100245-256)
Supplier: Southern Biotechnology
Description: Donkey Anti-Mouse IgG(H+L)-HRP antibody with minimal reactivity to human serum proteins for use in ELISA and immunohistochemistry / immunocytochemistry assays.


Catalog Number: (103265-722)
Supplier: Southern Biotechnology
Description: CD20 is a 33-37 kDa unglycosylated phosphoprotein. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. It is expressed on all stages of B cell differentiation except plasma cells. The CD20 molecule is involved in regulation of B cell differentiation presumably via its reported function as a Ca++ channel subunit.


Catalog Number: (100243-884)
Supplier: Southern Biotechnology
Description: The monoclonal antibody DX5 reacts with CD49b, also known as very late antigen-2 (VLA-2) and α2 integrin. The antibody stains the majority of NK cells and a small subpopulation of T cells in all mouse strains tested (e.g., A/J, AKR, BALB/c, C3H/HeJ, C57BL/6, C57BL/10, C57BR, C58, CBA/Ca, CBA/J, DBA/1, DBA/2, SJL, SWR). Three-color flow cytometry analysis has revealed that most cells that express NK-1.1 (NKR-P1C) also express CD49b. However, small subsets of DX5+NK-1.1- and DX5-NK-1.1+ cells can be found, especially among the CD3+ population of T lymphocytes. NK cells cultured in the presence of IL-2 progressively lose reactivity with DX5 as a consequence of cellular proliferation. Therefore, DX5 can be used to define functionally distinct subsets of murine NK cells. The monoclonal antibody DX5 has not been demonstrated to have activating or blocking activity.


Catalog Number: (103265-438)
Supplier: Southern Biotechnology
Description: CD107b, also known as lysosomal-associated membrane protein 2 (LAMP-2), is a heavily glycosylated type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains and is a ligand for E-selectin-mediated cell adhesion. CD107b is expressed in lysosomal/endosomal membranes and on the surface of activated platelets and some tumor cell lines including U937 and KG1a. LAMP-2 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential where they may increase adhesion to extracellular matrix and endothelium.


Catalog Number: (100243-630)
Supplier: Southern Biotechnology
Description: CD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the transferrin receptor. It is essential for the growth of normal and neoplastic cells. It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and mitogens presumably reflecting the iron dependence of proliferation. Its expression declines with maturation and differentiation. CD71 plays a critical role in cell proliferation by controlling the supply of iron which is essential for many metabolic pathways through the binding and endocytosis of transferrin, the major iron-carrying protein. It may also be involved in signal transduction via its association with the T cell receptor ζ chain. The monoclonal antibody RI7217 inhibits cell proliferation in vitro.


Catalog Number: (100245-388)
Supplier: Southern Biotechnology
Description: Feline CD5, a member of the scavenger receptor family of cell surface receptors, is a type I transmembrane glycoprotein that is expressed on most thymocytes and mature T lymphocytes. CD5 is thought to function in both cell-cell recognition and signal transduction. The monoclonal antibody f43 is useful as a pan T cell marker.


Catalog Number: (100242-354)
Supplier: Southern Biotechnology
Description: Biotin Anti-Human IL-13 antibody for use in ELISA assays.


Catalog Number: (103260-096)
Supplier: Southern Biotechnology
Description: Goat Anti-Rhesus IgG(H+L)-Alexa Fluor 647 antibody for use in immunocytochemistry and western blotting assays.


Catalog Number: (100242-566)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgA-Texas Red antibody for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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