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Catalog Number: (100244-924)
Supplier: Southern Biotechnology
Description: Rabbit F(ab')2 Anti-Human IgG(H+L)-HRP antibody with minimal reactivity to mouse proteins for use in ELISA assays.


Catalog Number: (103264-988)
Supplier: Southern Biotechnology
Description: Biotin Anti-Goat IgG Fc antibody for use in ELISA assays.


Catalog Number: (100245-534)
Supplier: Southern Biotechnology
Description: Purified Anti-Chicken Lambda antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and immunoprecipitation assays.


Catalog Number: (100242-406)
Supplier: Southern Biotechnology
Description: Purified Anti-Mouse IL-6 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, ELISA, ELISpot, and multiplex assays.


Catalog Number: (100242-260)
Supplier: Southern Biotechnology
Description: Bcl-2 is a 26 kDa member of the family of proteins involved in regulation of programmed cell death, or apoptosis. It is expressed in a variety of both normal and neoplastic tissues and appears to be membrane-bound since it is detectable in crude membrane and nuclear fractions, but not in the soluble fraction of cell lysates. Overexpression of Bcl-2 can prevent apoptosis, while formation of heterodimers with Bax, another Bcl-2-related protein, inhibits Bcl-2’s ability to promote cell survival.


Catalog Number: (103264-532)
Supplier: Southern Biotechnology
Description: CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3ε is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. 500-A2 recognizes an epitope on the 25 kDa ε chain of the CD3/TCR complex of mouse strains tested.


Catalog Number: (100243-776)
Supplier: Southern Biotechnology
Description: The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the costimulatory molecule CD28 and both molecules share common B7 family counter-receptors. However CD152 is thought to be a negative regulator of T cell activation and may play a role in apoptotic control of T cells. CD152 is relatively conserved among humans, mice, and chickens.


Catalog Number: (100242-574)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse Kappa-FITC antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100246-188)
Supplier: Southern Biotechnology
Description: CD16, a member of the immunoglobulin superfamily, is a 50-65 kDa glycoprotein found as both a transmembrane and GPI-linked form. The transmembrane form of CD16 is expressed on NK cells, granulocytes, macrophages, and mast cells but not on eosinophils. The GPI-anchored type of CD16 is found only on neutrophils. CD16 is involved in NK activation and signal transduction.


Catalog Number: (100244-588)
Supplier: Southern Biotechnology
Description: HRP Anti-Rat IgG1 antibody for use in ELISA, immunohistochemistry, and ELISpot assays.


Catalog Number: (100242-990)
Supplier: Southern Biotechnology
Description: Protein tyrosine residues are phosphorylated as a result of intracellular protein kinase activation (e.g., via growth factors) during normal growth and development and in oncogenesis. The most abundant population of target proteins for tyrosine phosphorylation is cell surface glycoproteins. Antibodies to phosphotyrosine enable the detection, isolation, and characterization of proteins containing phosphotyrosine. The monoclonal antibody PY20 prevents internalization of activated receptors (e.g., EGFR) when microinjected into cells. The affinity of PY20 for phosphotyrosine is approximately 10-6 to 10-7 M. PY20 binding to phosphorylated tyrosines can be inhibited by free phosphotyrosine and phenylphosphate but not by phosphoserine, phosphothreonine, or free phosphate.


Catalog Number: (100245-272)
Supplier: Southern Biotechnology
Description: Donkey Anti-Goat IgG(H+L)-PE antibody with minimal reactivity to mouse and rat serum proteins for use in flow cytometry and multiplex assays.


Catalog Number: (101190-240)
Supplier: Southern Biotechnology
Description: Low Endotoxin/Azide Free Anti-Mouse GM-CSF antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, ELISA, ELISpot, multiplex, and neutralization assays.


Catalog Number: (103264-546)
Supplier: Southern Biotechnology
Description: CD5, also known as Lyt-1, is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B-cell antigen CD72. The frequency of CD5+ B cells exhibits strain-dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells. Binding of CD5 on the T cell surface can augment alloantigen- or mitogen-induced lymphocyte proliferation and induces increased cytosolic free calcium, IL-2 secretion, and IL-2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T-cell and B-cell receptors.


Catalog Number: (100242-762)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Mouse IgE antibody for use in ELISA, flow cytometry, immunocytochemistry, western blotting, and immunoprecipitation assays.


Catalog Number: (101442-782)
Supplier: Southern Biotechnology
Description: The CD45 antigen is an essential regulator of leukocyte activation and development and is now known to be a protein tyrosine phosphatase, e.g., CD45 is able to dephosphorylate the Src family of protein kinases. This activity is now known to be required for signal transduction induced by T and B cell antigen receptor engagement, cytokine signaling, and Fc receptor stimulation. The functional state of CD45 also has a pronounced effect on lymphocyte development. CD45 exists in multiple forms, such as the restricted variants (CD45R; see companion products 1660, 1665, 1675, 1685, and 1820) and as allelic forms CD45.1 (Ly-5.1) and CD45.2 (Ly-5.2). The former arises as a result of alternative splicing of different exons. The specificity of antibodies to CD45.1 and CD45.2 has been exploited in studies where resolution of donor and recipient cells is essential, such as in gene therapy or bone marrow transplantation. The monoclonal antibody A20 recognizes all mouse leukocytes expressing the CD45.1 allotype.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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