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Catalog Number: (103265-160)
Supplier: Southern Biotechnology
Description: Alexa Fluor 647 Anti-Human IgM antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100243-756)
Supplier: Southern Biotechnology
Description: The TCRγδ heterodimer of the CD3/T cell receptor complex is clonotypic and consists of Ig-like variable and constant domains. It is expressed during thymopoiesis and on the small subpopulation of γδ TCR-expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are γδ+ and have limited receptor diversity. The TCRγδ heterodimer recognizes peptide antigen bound to MHC antigens and subsequent signal transduction mediated by the invariant chains leads to T cell activation. The monoclonal antibody UC7-13D5 is specific for the γδ heterodimer and plate-bound UC7-13D5 activates γδ TCR-bearing cells. This antibody does not react with αβ TCR-expressing T cells.


Catalog Number: (100243-622)
Supplier: Southern Biotechnology
Description: CD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the transferrin receptor. It is essential for the growth of normal and neoplastic cells. It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and mitogens presumably reflecting the iron dependence of proliferation. Its expression declines with maturation and differentiation. CD71 plays a critical role in cell proliferation by controlling the supply of iron which is essential for many metabolic pathways through the binding and endocytosis of transferrin, the major iron-carrying protein. It may also be involved in signal transduction via its association with the T cell receptor ζ chain. The monoclonal antibody RI7217 inhibits cell proliferation in vitro.


Supplier: Southern Biotechnology
Description: CD45R, also known as B220, a member of the protein tyrosine phosphate family and a major cell surface glycoprotein, represents a restricted form of the CD45 family which primarily recognizes only cells of B-lineage from pro-B cell through mature B lymphocytes and prior to the availability of anti-CD19 monoclonal antibodies was commonly used as a pan B-cell marker. It also reacts with certain activated T cells as well as non-MHC-restricted lytically active lymphokine-activated killer (LAK) cells. In vivo administration of RA3-6B2 has been shown to affect differentiation of both T and B cells in normal mice and reduce the level of anti-DNA antibodies and lymphadenopathies in MRL/lpr mice.

Catalog Number: (101442-794)
Supplier: Southern Biotechnology
Description: CD24 is expressed in B cells until their terminal differentiation into plasma cells. It has been used widely as a marker to fractionate different B-lineage differentiation stages. CD24 has been found on a variety of other hematopoietic and neural cell types and is now classified as a costimulatory molecule. The CD24 molecule, also known as HSA, is composed mostly of carbohydrate with a protein core of only 31-35 amino acids in the human and 27 amino acids in the mouse. CD24 is now included in the large group of phosphatidylinositol-anchored membrane proteins. Studies with purified CD24 applied to latex beads have demonstrated a self-binding property suggesting that the molecule is capable of promoting homotypic aggregation, binding, and cell adhesion. This is supported by earlier observations of the blockade of B cell lymphoblast aggregation with an anti-CD24 monoclonal antibody. Recent studies of murine CD24 have assigned a role for CD24 as a ligand for P-selectin, a calcium-dependent lectin.


Catalog Number: (101442-980)
Supplier: Southern Biotechnology
Description: CD45, also known as the leukocyte common antigen (LCA), exists as four different isoforms (180, 190, 205, 220 kDa) that are generated by alternative splicing of three exons. LCA is found on all cells of hematopoietic origin, except erythrocytes and platelets. CD45 expression is required for T cell and B cell antigen receptor-mediated activation.


Catalog Number: (103259-732)
Supplier: Southern Biotechnology
Description: Rat IgG2c-Alexa Fluor 700 for use as a control in flow cytometry assays.


Catalog Number: (100242-744)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG3-Texas Red antibody with minimal reactivity to human proteins for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.


Catalog Number: (103265-190)
Supplier: Southern Biotechnology
Description: Biotin Anti-Human IgG1 Fc antibody for use in ELISA, flow cytometry, western blotting, and multiplex assays.


Catalog Number: (100244-720)
Supplier: Southern Biotechnology
Description: Goat Anti-Rabbit Ig-TRITC antibody with minimal reactivity to human proteins for use in immunohistochemistry / immunocytochemistry assays.


Catalog Number: (103265-286)
Supplier: Southern Biotechnology
Description: CD8 is a 33 kDa transmembrane glycoprotein expressed as either a CD8αα homodimer or CD8αβ heterodimer. It is expressed on the “cytotoxic/suppressor” subpopulation of peripheral T cells. CD8 functions primarily as a coreceptor with MHC class I-restricted TCR’s in antigen recognition.


Catalog Number: (100242-536)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Mouse IgG(H+L)-CY5 antibody with minimal reactivity to human proteins for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (103265-102)
Supplier: Southern Biotechnology
Description: Purified Donkey Anti-Rabbit IgG(H+L) antibody with minimal reactivity to human, mouse, rat, bovine, horse, hamster, goat, sheep, chicken, and guinea pig serum proteins for use in ELISA and immunohistochemistry / immunocytochemistry assays.


Catalog Number: (100242-778)
Supplier: Southern Biotechnology
Description: Low Endotoxin/Azide Free Anti-Mouse IgD antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, separation, costimulation, and proximity ligation assays.


Catalog Number: (100242-676)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG2a-TRITC antibody with minimal reactivity to human proteins for use in immunohistochemistry / immunocytochemistry assays.


Catalog Number: (100244-634)
Supplier: Southern Biotechnology
Description: Purified F(ab')2 Anti-Rat IgM antibody for use in flow cytometry, ELISA, and stimulation assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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