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Supplier: Southern Biotechnology
Description: Gelatin Subbed Slides are subbed with a solution of 0.1% gelatin and chromium potassium sulfate.

Catalog Number: (103265-504)
Supplier: Southern Biotechnology
Description: Alexa Fluor 488 Anti-Mouse IFN-gamma antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100246-514)
Supplier: Southern Biotechnology
Description: CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107a is expressed by activated T cells, macrophages, dendritic cells, activated platelets, tonsillar epithelium, and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential where they may increase adhesion to extracellular matrix and endothelium.


Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgM-APC antibody with minimal reactivity to human proteins for use in flow cytometry assays.

Catalog Number: (103264-712)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgG Fc-HRP antibody with minimal reactivity to rabbit, mouse, rat, bovine, horse, hamster, goat, sheep, chicken, and guinea pig serum proteins for use in ELISA assays.


Catalog Number: (100243-406)
Supplier: Southern Biotechnology
Description: CD30 is a type I transmembrane protein and a member of the tumor necrosis factor receptor superfamily of proteins. Murine CD30 is expressed predominantly in the thymus and it is inducible in mouse splenocytes stimulated with pokeweed mitogen or concanavalin A. In anti-CD3ε-activated spleen cells, CD30 is expressed primarily on the surface of CD8+ T cells with peak expression on days 4 and 5. Stimulation of CD30+ CTL lines with plate-bound anti-CD30 directly signals IL-5 but not IFN-γ production. While these studies demonstrate that CD30 directs cytokine secretion and suggest that CD30 may play a pivotal role in the pattern of cytokine production by T cells, the precise roles of CD30 and its ligand (CD153) in T-cell development have not been clearly defined.


Catalog Number: (103264-718)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgG Fc-Alexa Fluor 647 antibody with minimal reactivity to rabbit, mouse, rat, bovine, horse, hamster, goat, sheep, chicken, and guinea pig serum proteins for use in flow cytometry and other fluorescent assays.


Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG2a-PE antibody with minimal reactivity to human proteins for use in flow cytometry assays.

Catalog Number: (103264-972)
Supplier: Southern Biotechnology
Description: Purified Rabbit Anti-Human IgG(H+L) antibody with minimal reactivity to mouse, bovine, and horse serum proteins for use in ELISA assays.


Catalog Number: (103259-896)
Supplier: Southern Biotechnology
Description: CD11b (integrin αM subunit) combines with CD18 (integrin β2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.


Catalog Number: (100242-030)
Supplier: Southern Biotechnology
Description: Goat F(ab’)2 IgG-FITC for use as a control in flow cytometry and immunocytochemistry assays.


Catalog Number: (100243-510)
Supplier: Southern Biotechnology
Description: CD45 is the common leukocyte antigen and is expressed on all cells of hematopoietic origin except erythrocytes. CD45 exists as a number of different isoforms which result from alternative RNA splicing of exons 4, 5 and 6. The I3/2.3 monoclonal antibody recognizes a framework epitope present on all CD45 isoforms. The CD45 molecule has been implicated as playing a key role in thymic development and in antigen-driven proliferation of T cells.


Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG1-PE antibody with minimal reactivity to human proteins for use in flow cytometry and multiplex assays.

Catalog Number: (100243-494)
Supplier: Southern Biotechnology
Description: CD154, formerly known as CD40 ligand and gp39, is a type II integral membrane protein and a member of the tumor necrosis factor (TNF) family of ligands. It is an important accessory molecule in T cell-B cell costimulatory interactions and is expressed predominantly on activated CD4+ T lymphocytes. It is also present on the surface of activated Th0, Th1, and Th2 T cell clones. Its expression is transient and cyclosporin-sensitive. The MR1 monoclonal antibody binds to murine CD154 with high affinity, blocks binding to CD40, and blocks CD154 function. Administration of this antibody to mice blocks the ability to mount primary and secondary immune responses to TD antigens yet does not alter the immune response to TI antigens.


Catalog Number: (100244-744)
Supplier: Southern Biotechnology
Description: Goat Anti-Rabbit IgM-HRP antibody for use in ELISA, immunohistochemistry, western blotting, and ELISpot assays.


Catalog Number: (100246-052)
Supplier: Southern Biotechnology
Description: CD4 is a 55 kDa type I transmembrane glycoprotein and a member of the Ig-SF of cell surface receptors. It is expressed predominantly on the “helper/inducer” subpopulation of mature T lymphocytes and on monocytes and macrophages. Domains 1 and 2 bind to MHC Class II antigens, while domains 3 and 4 may be involved in cis interactions with the CD3/TCR complex. CD4 functions as an accessory molecule in the recognition of foreign antigens in association with MHC class II antigens by T cells.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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