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Supplier: Southern Biotechnology
Description: CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.

Catalog Number: (103260-062)
Supplier: Southern Biotechnology
Description: Mouse Anti-Rabbit IgG(H+L)-Biotin antibody with minimal reactivity to mouse, human, goat, and sheep serum proteins for use in ELISA assays.


Catalog Number: (103264-792)
Supplier: Southern Biotechnology
Description: Goat Anti-Human Ig Fab-FITC antibody for use in fluorescent assays.


Catalog Number: (103264-388)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Mouse IgG(H+L)-Alexa Fluor 555 antibody with minimal reactivity to human proteins for use in immunohistochemistry / immunocytochemistry and western blotting assays.


Catalog Number: (103265-506)
Supplier: Southern Biotechnology
Description: Alexa Fluor 647 Anti-Mouse IFN-gamma antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (103264-904)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Rabbit IgG(H+L) antibody for use in ELISA assays.


Catalog Number: (100244-830)
Supplier: Southern Biotechnology
Description: Porcine CD3ε is a member of the T-cell receptor-associated CD3 complex. It is found on a subpopulation of thymocytes and on all pig T lymphocytes. The monoclonal antibody PPT3 is mitogenic when presented to peripheral blood mononuclear cells in immobilized form.


Catalog Number: (100241-974)
Supplier: Southern Biotechnology
Description: Mouse IgA-PE for use as a control in flow cytometry assays.


Catalog Number: (101442-494)
Supplier: Southern Biotechnology
Description: DAPI Fluoromount-G® is suitable for mounting frozen and paraffin sections, whole mounts, and cells.


Catalog Number: (103264-680)
Supplier: Southern Biotechnology
Description: Purified Anti-Hamster IgG2/IgG3 antibody for use in ELISA and flow cytometry assays.


Catalog Number: (101190-320)
Supplier: Southern Biotechnology
Description: Purified Anti-Rabbit IgG antibody for use in ELISA, flow cytometry, immunohistochemistry, and western blotting assays.


Catalog Number: (100244-540)
Supplier: Southern Biotechnology
Description: Goat Anti-Rat IgG-FITC antibody with minimal reactivity to mouse proteins for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100242-174)
Supplier: Southern Biotechnology
Description: Purified Human IgG1 Lambda for use as a standard in ELISA.


Catalog Number: (100246-526)
Supplier: Southern Biotechnology
Description: CD107b, also known as lysosomal-associated membrane protein 2 (LAMP-2), is a heavily glycosylated type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains and is a ligand for E-selectin-mediated cell adhesion. CD107b is expressed in lysosomal/endosomal membranes and on the surface of activated platelets and some tumor cell lines including U937 and KG1a. LAMP-2 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential where they may increase adhesion to extracellular matrix and endothelium.


Catalog Number: (100243-452)
Supplier: Southern Biotechnology
Description: Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR) and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCRαβ+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B and T cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.


Catalog Number: (100242-034)
Supplier: Southern Biotechnology
Description: Goat F(ab’)2 IgG-APC for use as a control in flow cytometry assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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