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Catalog Number: (100244-580)
Supplier: Southern Biotechnology
Description: Biotin Anti-Rat IgG1 antibody for use in flow cytometry, ELISA, and immunohistochemistry assays.


Catalog Number: (100243-678)
Supplier: Southern Biotechnology
Description: CD90 (Thy-1), a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes, and neurons of all mouse strains. The monoclonal antibody G7 stimulates T-cell proliferation and IL-2 secretion via signaling through the T-cell receptor/CD3 complex. G7 has also been reported to promote apoptosis of thymocytes and CTL clones and to mediate adhesion of thymocytes to thymic stroma.


Supplier: Southern Biotechnology
Description: CD44, also known as phagocytic glycoprotein-1 (Pgp-1), exists as a large number of different isoforms resulting from alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type I transmembrane protein. Other variable isoforms containing glycosaminoglycans have molecular weights ranging from 110 to 250 kDa and are widely expressed on hematopoietic and non-hematopoietic cells. CD44 contributes to the adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. It also plays a functional role in cell migration, lymphocyte homing, and adhesion during hematopoiesis and lymphocyte activation.

Catalog Number: (100244-576)
Supplier: Southern Biotechnology
Description: FITC Anti-Rat IgG1 antibody for use in flow cytometry and immunohistochemistry assays.


Catalog Number: (103264-174)
Supplier: Southern Biotechnology
Description: Mouse IgG3-Alexa Fluor 647 for use as a control in flow cytometry and immunocytochemistry assays.


Catalog Number: (103259-768)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG1-Biotin antibody with minimal reactivity to human, bovine, and horse serum proteins for use in ELISA assays.


Catalog Number: (103264-920)
Supplier: Southern Biotechnology
Description: Alexa Fluor 555 Anti-Monkey IgG for use in fluorescent assays.


Catalog Number: (100244-646)
Supplier: Southern Biotechnology
Description: PE Anti-Rat Kappa antibody for use in flow cytometry assays.


Catalog Number: (103264-594)
Supplier: Southern Biotechnology
Description: The monoclonal antibody 5H10.27 reacts with the α5 chain (VLA-5) of the CD49e/CD29 heterodimeric fibronectin receptor. It is expressed on thymocytes, activated T cells, mast cells, and a variety of mouse cell lines. Soluble 5H10.27 antibody inhibits VLA-5-mediated functions in vitro. Immobilized 5H10.27 has also been demonstrated to costimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3 monoclonal antibody.


Catalog Number: (103265-598)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG1-HRP antibody for use in ELISA and immunocytochemistry assays.


Supplier: Southern Biotechnology
Description: CD90 (Thy-1) is a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily consisting of a single V-set domain. The Thy-1.2 alloantigen is expressed on all thymocytes, peripheral T lymphocytes, and some intraepithelial T cells of most mouse strains. It is also expressed in the brain and at varying levels on other non-lymphoid tissues. The 30-H12 monoclonal antibody does not cross react with mouse and rat strains bearing the Thy-1.1 alloantigen (e.g., AKR/J, PL).

Catalog Number: (103265-686)
Supplier: Southern Biotechnology
Description: FITC Anti-Human IgE antibody for use in western blotting assays.


Catalog Number: (100243-996)
Supplier: Southern Biotechnology
Description: The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid production of primitive hematopoietic progenitor cells. A variety of cytokines act synergistically with SCF to stimulate proliferation and differentiation of bone marrow progenitor cells. For example, SCF plus IL-7 can stimulate the combined myeloid and B cell differentiation of uncommitted hematopoietic progenitor cells. SCF/c-Kit also participates in erythropoiesis in both the bone marrow and spleen. Loss-of-function mutations for SCF/c-Kit lead to a variety of pleiotropic developmental defects while gain-of-function mutations can lead to constitutive activation of the kit receptor and links to cancer. Examples of the former are mast cell deficiency and severe macrocytic anemia while the latter mutation has been identified in mastocytomas.


Catalog Number: (100243-452)
Supplier: Southern Biotechnology
Description: Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR) and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCRαβ+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B and T cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.


Catalog Number: (100241-880)
Supplier: Southern Biotechnology
Description: Mouse IgM-Biotin for use as a control in flow cytometry and immunohistochemistry assays.


Catalog Number: (100245-710)
Supplier: Southern Biotechnology
Description: Purified Anti-Human IgG1 Hinge antibody for use in ELISA, flow cytometry, immunohistochemistry, western blotting, separation, purification, and multiplex assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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