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Image Unavailable-103264-652

Anti-Ly-6G/Ly-6C Rat Monoclonal Antibody (Alexa Fluor® 700) [clone: RB6-8C5]

Catalog Number: (103264-652)
Supplier: Southern Biotechnology
Description: Ly-6G/Ly-6C, formerly known as the myeloid differentiation antigen Gr-1, is a GPI-anchored protein. In the bone marrow, the level of antigen expression is directly correlated with granulocyte differentiation and maturation. It is also transiently expressed on monocytes in the bone marrow. In the periphery, Ly-6G/Ly-6C is expressed predominantly on neutrophils.
Image Unavailable-103260-014

Anti-Lambda Goat Antibody (Alexa Fluor® 647)

Catalog Number: (103260-014)
Supplier: Southern Biotechnology
Description: Goat Anti-Human Lambda-Alexa Fluor 647 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
Image Unavailable-103264-538

Anti-CD4 Rat Monoclonal Antibody (Alexa Fluor® 700) [clone: GK1.5]

Catalog Number: (103264-538)
Supplier: Southern Biotechnology
Description: CD4 is a type I transmembrane glycoprotein expressed on most thymocytes and the helper/inducer subpopulation of mature T lymphocytes of all mouse strains tested. CD4 has also been detected at low density on pluripotent hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic lymphoid precursors. The CD4 antigen functions as a co-receptor, interacting with class II major histocompatability complex (MHC) molecules in the recognition of foreign antigens by T cells. In vivo and in vitro treatment with the GK1.5 monoclonal antibody effectively depletes CD4+ cells. GK1.5 also blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.
Image Unavailable-103265-220

Anti-IgG4 F(c) Mouse Antibody (Alexa Fluor® 488) [clone: HP6025]

Catalog Number: (103265-220)
Supplier: Southern Biotechnology
Description: Alexa Fluor 488 Anti-Human IgG4 Fc antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
Image Unavailable-103264-928

Anti-IgG (H+L) Rabbit Antibody (Alexa Fluor® 488)

Catalog Number: (103264-928)
Supplier: Southern Biotechnology
Description: Rabbit F(ab')2 Anti-Human IgG(H+L)-Alexa Fluor 488 antibody for use in immunocytochemistry and western blotting assays.
Image Unavailable-100243-820

Anti-CD45.2 Mouse Monoclonal Antibody (Cy5®) [clone: 104]

Catalog Number: (100243-820)
Supplier: Southern Biotechnology
Description: The CD45 antigen is an essential regulator of leukocyte activation and development and is now known to be a protein tyrosine phosphatase, e.g., CD45 is able to dephosporylate the Src family of protein kinases. This activity is known to be required for signal transduction induced by T and B cell antigen receptor engagement, cytokine signaling, and Fc receptor stimulation. The functional state of CD45 also has a pronounced effect on lymphocyte development. CD45 exists in multiple forms, such as the restricted variants (CD45R; see companion products 1660, 1665, 1675, 1685 and 1820) and as allelic forms CD45.1 (Ly-5.1) and CD45.2 (Ly-5.2). The specificity of antibodies to CD45.1 and CD45.2 has been exploited in studies where resolution of donor and recipient cells is essential, such as in gene therapy or bone marrow transplantation. The monoclonal antibody 104 recognizes CD45 (leukocyte common antigen) on all leukocytes of mouse strains expressing the CD45.2 allotype (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129).
Image Unavailable-101442-958

Anti-CD14 Mouse Monoclonal Antibody (RPE (R-Phycoerythrin)/Cy7®) [clone: 61D3]

Catalog Number: (101442-958)
Supplier: Southern Biotechnology
Description: CD14 is a 55 kDa glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells, and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.
Image Unavailable-100245-900

Anti-CD19 Mouse Monoclonal Antibody (Spectral Red® RPE (R-Phycoerythrin)/Cy5®) [clone: SJ25-C1]

Catalog Number: (100245-900)
Supplier: Southern Biotechnology
Description: CD19 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is expressed at all stages of B cell differentiation except terminally differentiated plasma cells. It is also present on the cell surface of follicular dendritic cells. CD19 associates with CD21, CD81, Leu 13 and/or MHC Class II molecules to form a signal transduction complex on the B cell surface. This signaling complex modulates the activation threshold for the B cell antigen receptor (BCR).
Image Unavailable-100243-948

Anti-CD81 Hamster Monoclonal Antibody (RPE (R-Phycoerythrin)) [clone: 2F7]

Catalog Number: (100243-948)
Supplier: Southern Biotechnology
Description: CD81, also known as TAPA-1, is an integral membrane protein expressed on a variety of cell types and has a high degree of sequence homology between human and mouse. CD81 is expressed on thymic stromal cells where it plays an important role in the transition of γδ+ T cells to more mature T cells with αβ T cell receptors. Immunohistochemical staining has revealed that its expression is localized to the subcapsular region of the thymus and, specifically, on cells that have distinct clustering patterns. It has been speculated that the ligand for CD81 is the pre-T cell receptor which is composed of a TCR β chain and glycoprotein pTα. The monoclonal antibody 2F7 can block thymocyte interaction with CD81 in vitro.
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Anti-CD158e1 Mouse Monoclonal Antibody (Alexa Fluor® 488) [clone: DX9]

Catalog Number: (103265-450)
Supplier: Southern Biotechnology
Description: CD158e1 is a 70 kDa transmembrane glycoprotein and a killer cell immunoglobulin (Ig)-like receptor (KIR) that is expressed on a subset of natural killer cells and T cells. The monoclonal antibody DX9 is expressed on a subset of CD3-, CD56+ NK cells isolated from peripheral blood at varying levels (<0.1% to 61%) among individuals but not on thymocytes, B lymphocytes, granulocytes, or monocytes. Interactions with CD158e1 and certain MHC HLA-B antigens on a target cell inhibits cytotoxicity, possibly preventing target cell lysis and death. KIR and MHC class I interactions may regulate NK and T cell response to antigen stimulation.
Image Unavailable-100241-994

Mouse IgG Isotype Control (APC (Allophycocyanin))

Catalog Number: (100241-994)
Supplier: Southern Biotechnology
Description: Mouse IgG-APC for use as a control in flow cytometry assays.
Image Unavailable-100244-218

Anti-IgM Goat Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (100244-218)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgM-HRP antibody for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.
Image Unavailable-100245-670

Anti-IgD Mouse Antibody [clone: IADB6]

Catalog Number: (100245-670)
Supplier: Southern Biotechnology
Description: Purified Anti-Human IgD antibody for use in ELISA, flow cytometry, immunohistochemistry, immunoprecipitation, costimulation, and separation assays.
Image Unavailable-103259-664

Anti-IL-33 Mouse Monoclonal Antibody [clone: SB127j]

Catalog Number: (103259-664)
Supplier: Southern Biotechnology
Description: Interleukin-33 (IL-33), also known as NF-HEV, is a 30 kDa protein and a member of the IL-1 family. This pro-inflammatory cytokine is produced by a variety of cells but is primarily expressed by endothelial and smooth muscle cells in the vasculature and airways. IL-33 binds to the ST2 receptor on target cells which results in the activation of multiple signaling pathways including NF-κB and MAP kinases. Studies have shown that IL-33 promotes T helper type 2 (Th2) cell-mediated immune responses and upregulates production of Th2 associated cytokines including IL-4, IL-5, and IL-13. In vivo administration of this cytokine in mice results in eosinophilia and splenomegaly as well as induced severe pathological changes in the lungs, gastrointestinal tract, and other mucosal organs.
Image Unavailable-103264-800

Anti-IgG (H+L) Goat Antibody

Catalog Number: (103264-800)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Human IgG(H+L) antibody with minimal reactivity to rabbit, mouse, rat, bovine, horse, hamster, goat, sheep, chicken, and guinea pig serum proteins for use in ELISA assays.
Image Unavailable-100245-780

Anti-IgE F(c) Mouse Antibody (AP (Alkaline Phosphatase)) [clone: B3102E8]

Catalog Number: (100245-780)
Supplier: Southern Biotechnology
Description: AP Anti-Human IgE Fc antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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