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Catalog Number: (100242-578)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse Kappa-AP antibody for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.


Catalog Number: (100244-408)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Rat Ig antibody with minimal reactivity to mouse proteins for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and depletion assays.


Catalog Number: (100243-112)
Supplier: Southern Biotechnology
Description: CD4 is a type I transmembrane glycoprotein expressed on most thymocytes and the helper/inducer subpopulation of mature T lymphocytes of all mouse strains tested. CD4 has also been detected at low density on pluripotent hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic lymphoid precursors. The CD4 antigen functions as a co-receptor, interacting with class II major histocompatability complex (MHC) molecules in the recognition of foreign antigens by T cells. In vivo and in vitro treatment with the GK1.5 monoclonal antibody effectively depletes CD4+ cells. GK1.5 also blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.


Catalog Number: (100245-846)
Supplier: Southern Biotechnology
Description: Purified Anti-Human IgE antibody for use in ELISA, ELISpot, purification, and stimulation assays.


Catalog Number: (103260-072)
Supplier: Southern Biotechnology
Description: Porcine CD8, a type I transmembrane glycoprotein, is expressed as either a CD8αα homodimer or a CD8αβ heterodimer. It is found on most thymocytes and on the suppressor/cytotoxic subpopulation of peripheral T cells. CD8 functions primarily as a co-receptor with MHC Class I-restricted T cell receptors in antigen recognition. The monoclonal antibody 76-2-11 reacts with the CD8 α-chain.


Catalog Number: (100243-348)
Supplier: Southern Biotechnology
Description: The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity α chain of the IL-2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O-linked carbohydrates and has a short cytoplasmic tail. CD25 is expressed on activated T cells, B cells, NK cells, and monocytes of all mouse strains tested. It is transiently expressed at a low level during B cell development in bone marrow on the CD45R/B220low TdT- sIg- pre-B II and CD45R/B220low TdT- sIgM+sIgD- immature B cells, but not on the CD45R/B220low TdT+ sIg- pro-B/pre-B I stage nor on CD45R/B220high TdT- sIgM+sIgD+ mature B cells. CD25 is expressed at a higher level during very early T-cell development in fetal and adult thymus. The 7D4 monoclonal antibody reacts with an epitope between amino acids 125 and 212 that is distinct from that recognized by the monoclonal antibody 3C7 (SB Cat. No. 1600). While the monoclonal antibody 7D4 does not block the binding of IL-2 to CD25, when used in combination with the monoclonal antibody 3C7 it results in higher levels of inhibition of IL-2-driven proliferation than either of these two monoclonal antibodies alone.


Catalog Number: (100244-270)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgG-β-galactosidase antibody for use in ELISA and immunohistochemistry / immunocytochemistry assays.


Catalog Number: (103260-144)
Supplier: Southern Biotechnology
Description: In the chicken, the CD8 molecule is present in two forms - (i) a homodimer of two α chains and (ii) a heterodimer of an α chain and a β chain. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8α- and CD8β-chains, a relatively large proportion of the CD8+ TCRγδ cells in the spleens of embryos and young chicks express only the α-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved but there is a population of TCRγδ CD8αβ cells in the chicken that is not found in rodents. Chicken CD8 is expressed on approximately 80% of thymocytes, 15% of blood mononuclear cells, and 50% of spleen cells but less than 1% of cells in the bursa and bone marrow. The monoclonal antibody CT-8 recognizes the CD8α chain and has been shown to react to a polymorphic determinant in turkey.


Catalog Number: (100242-646)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG1-Biotin antibody with minimal reactivity to human proteins for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, electron microscopy, western blotting, ELISpot, and multiplex assays.


Catalog Number: (103265-336)
Supplier: Southern Biotechnology
Description: CD15 is a carbohydrate antigen found on the cell surface of neutrophils and monocytes, but not on basophils, platelets, lymphocytes, or erythrocytes. CD15 may function in adhesion as its ligand is L-selectin (CD62L).


Catalog Number: (103260-058)
Supplier: Southern Biotechnology
Description: Alexa Fluor 555 Anti-Rabbit IgG antibody for use in immunohistochemistry and western blotting assays.


Catalog Number: (103260-128)
Supplier: Southern Biotechnology
Description: Donkey Anti-Mouse IgG(H+L)-Alexa Fluor 488 antibody with minimal reactivity to human serum proteins for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.


Supplier: Southern Biotechnology
Description: CD11c is a 150 kDa adhesion glycoprotein that associates with β2 integrin to form the CD11c/CD18 heterodimer that binds CD54 (ICAM-1) and fibrinogen. It is expressed on NK cells, a subset of B and T cells, granulocytes, monocytes, and macrophages. It functions in cytotoxic T cell killing and in neutrophil and monocyte adhesion to endothelium.

Catalog Number: (103264-192)
Supplier: Southern Biotechnology
Description: Low Endotoxin/Azide Free Rabbit IgG for use as a control in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, ChIP, microarray, and in vivo / in vitro assays and as a standard in ELISA.


Catalog Number: (103260-104)
Supplier: Southern Biotechnology
Description: Rabbit Anti-Hamster IgG(H+L)-HRP antibody with minimal reactivity to mouse and rat serum proteins for use in ELISA, immunohistochemistry, and western blotting assays.


Catalog Number: (100242-568)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgA-Biotin antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, ELISpot, and separation assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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