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Catalog Number: (100245-772)
Supplier: Southern Biotechnology
Description: HRP Anti-Human IgA2 antibody for use in ELISA, immunohistochemistry, western blotting, and ELISpot assays.


Catalog Number: (100245-694)
Supplier: Southern Biotechnology
Description: FITC Anti-Human IgG Fc antibody for use in flow cytometry and western blotting assays.

Catalog Number: (100243-856)
Supplier: Southern Biotechnology
Description: The monoclonal antibody 20d5 reacts with an epitope common to the NKG2A, NKG2C and NKG2E isoforms of the NKG2 heterodimer, a member of the c-type lectin family of inhibitory receptors. Mouse NKG2 is a natural killer (NK) cell receptor for the non-classical MHC class I molecule Qa-1b. NKG2 is expressed on NK cells, lymphokine-activated killer (LAK) T cells, and some CD8+ memory T cells. Two-color immunofluorescent staining with the 20d5 antibody reveals two distinct NKG2+ phenotypes within the NK1.1+CD3- spleen cell population: NKG2hi (50%) and NKG2low (50%). With the exception of DBA/2J mice, NKG2 is expressed on NK1.1+ cells from all mouse strains tested (C57BL/6, BALB/c, 129/J, C3H.SW, AKR/J, SJL).


Catalog Number: (100242-682)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG2a-Texas Red antibody with minimal reactivity to human proteins for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.


Catalog Number: (101442-618)
Supplier: Southern Biotechnology
Description: Low Endotoxin/Azide Free Anti-Mouse IL-4 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, ELISA, ELISpot, multiplex, and neutralization assays.


Catalog Number: (103265-240)
Supplier: Southern Biotechnology
Description: APC Anti-Human Kappa antibody for use in flow cytometry assays.


Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG2a-PE antibody with minimal reactivity to human proteins for use in flow cytometry assays.

Supplier: Southern Biotechnology
Description: CD45 is the common leukocyte antigen and is expressed on all cells of hematopoietic origin except erythrocytes. CD45 exists as a number of different isoforms which result from alternative RNA splicing of exons 4, 5 and 6. The I3/2.3 monoclonal antibody recognizes a framework epitope present on all CD45 isoforms. The CD45 molecule has been implicated as playing a key role in thymic development and in antigen-driven proliferation of T cells.

Catalog Number: (100246-176)
Supplier: Southern Biotechnology
Description: CD14 is a 55 kDa glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells, and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.


Catalog Number: (103264-646)
Supplier: Southern Biotechnology
Description: The monoclonal antibody 11-4.1 reacts with the H-2Kk MHC class I alloantigen. The antibody may react with other (e.g., p, q, and r) haplotypes.


Catalog Number: (100242-188)
Supplier: Southern Biotechnology
Description: Human IgA Lambda-AP for use as a control in ELISA assays.


Catalog Number: (100243-586)
Supplier: Southern Biotechnology
Description: CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes, and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN γ, IL-1, TNF-α, lipopolysaccharide, and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1.


Catalog Number: (100244-094)
Supplier: Southern Biotechnology
Description: The “classical” MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic α chains noncovalently associated with the invariant β2-microglobulin. These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+ T lymphocytes which are usually cytotoxic T cells. MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+ T cells during T cell ontogeny. The monoclonal antibody 28-14-8 binds to the α3 domain of H-2Db in the presence or absence of β2 microglobulin. It cross reacts with the α3 domain of H-2Ld, but not Kd or Dd, and with H-2Dq and/or Lq. The antibody has been shown to block H-2Ld-specific and H-2Ld-restricted antigen-specific lysis of target cells by cytotoxic T lymphocytes but it does not block recognition of H-2Ld-positive target cells by Ly-6G2-positive NK cells.


Catalog Number: (103264-738)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgM-Alexa Fluor 488 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (103259-666)
Supplier: Southern Biotechnology
Description: Interleukin-33 (IL-33), also known as NF-HEV, is a 30 kDa protein and a member of the IL-1 family. This pro-inflammatory cytokine is produced by a variety of cells but is primarily expressed by endothelial and smooth muscle cells in the vasculature and airways. IL-33 binds to the ST2 receptor on target cells which results in the activation of multiple signaling pathways including NF-κB and MAP kinases. Studies have shown that IL-33 promotes T helper type 2 (Th2) cell-mediated immune responses and upregulates production of Th2 associated cytokines including IL-4, IL-5, and IL-13. In vivo administration of this cytokine in mice results in eosinophilia and splenomegaly as well as induced severe pathological changes in the lungs, gastrointestinal tract, and other mucosal organs.


Catalog Number: (101190-316)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Human Kappa-AP antibody with minimal reactivity to mouse proteins for use in ELISA and ELISpot assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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