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Description: GnRH-Receptor (LHRH Receptor), Monoclonal antibody, Clone: GNRHR/768, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, BSA-free, Immunogen: A synthetic peptide aa 1-29 from the N-terminal of human GnRH receptor, Application: IF, Flow cytometry, Size: 50 uL

Catalog Number: 75948-890

Supplier: Biotium

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Description: This antibody recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR). Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH). GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Catalog Number: 75948-852

Supplier: Biotium

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Description: GnRH-Receptor (LHRH Receptor), Monoclonal antibody, Clone: F1G4, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: A synthetic peptide aa 1-29 from the N-terminal of human GnRH receptor, Application: IF, Flow, Size: 100uL

Catalog Number: 75948-868

Supplier: Biotium

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Description: GnRH-Receptor (LHRH Receptor), Monoclonal antibody, Clone: GNRHR/768, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: A synthetic peptide aa 1-29 from the N-terminal of human GnRH receptor, Application: IF, Flow, Size: 100uL

Catalog Number: 75948-934

Supplier: Biotium

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Description: GnRH-Receptor (LHRH Receptor), Monoclonal antibody, Clone: GNRHR/768, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: A synthetic peptide aa 1-29 from the N-terminal of human GnRH receptor, Application: IF, Flow, Size: 100uL

Catalog Number: 75948-944

Supplier: Biotium

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Description: Golgi Complex, Monoclonal antibody, Clone: 371-4, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: SU-DHL-1 large cell lymphoma cells, Synonyms: Golgi Complex; Golgi apparatus; Golgi zone, Size: 100uL

Catalog Number: 75948-992

Supplier: Biotium

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Description: Golgi Complex, Monoclonal antibody, Clone: 371-4, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: SU-DHL-1 large cell lymphoma cells, Synonyms: Golgi Complex; Golgi apparatus; Golgi zone, Size: 100uL

Catalog Number: 75949-000

Supplier: Biotium

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Description: Granulocyte Marker, Monoclonal antibody, Clone: BM-2, Host: Mouse, Species reactivity: Human, Isotype: IgG1, Conjugate: biotin, Immunogen: Human peripheral blood mononuclear cells, Synonyms: Myeloid specific protein; p183 DNA-binding cytoplasmic protein, Size: 100uL

Catalog Number: 75949-228

Supplier: Biotium

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Description: This antibody recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Catalog Number: 75949-378

Supplier: Biotium

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Description: Helicobacter pylorI, Monoclonal antibody, Clone: HP/212, Host: Mouse, Species reactivity: Helicobacter pylori, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Total sonicate of Helicobacter pylori, Synonyms: H. Pylori, Application: IF, Size: 100uL

Catalog Number: 75949-880

Supplier: Biotium

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Description: HCG-alphA, Monoclonal antibody, Clone: HCGa/53, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Recombinant hCG alpha protein, Application: Immunohistology (formalin), Size: 100uL

Catalog Number: 75949-978

Supplier: Biotium

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Description: Glucose Regulated Protein 94 (GRP94), Monoclonal antibody, Clone: HSP90B1/1192, Host: Mouse, Species reactivity: Horse, Monkey, Pig, Dog, Cow, Sheep, Rat, Human, Guinea Pig, Isotype: IgM, kappa, Conjugate: purified, Immunogen: Purified (grp94), Size: 100uL

Catalog Number: 75949-646

Supplier: Biotium

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Description: This antibody recognizes a protein of 94 kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp s are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Catalog Number: 75949-580

Supplier: Biotium

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Description: This antibody recognizes a protein of 94 kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp s are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.

Catalog Number: 75949-614

Supplier: Biotium

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Description: Glycophorin A / CD235A, Monoclonal antibody, Clone: GYPA/280, Host: Mouse, Species reactivity: Human, Isotype: IgM, kappa, Conjugate: CF594, Immunogen: Human erythrocytes treated with neuraminidase, Synonyms: Blood group-MN locus; GPA; GPErik, GPSAT, Size: 500uL

Catalog Number: 75949-794

Supplier: Biotium

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Description: This MAb reacts with a protein of 22 kDa, identified as β sub-unit of HCG. It does not cross react with the α sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The beta subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Catalog Number: 75950-004

Supplier: Biotium

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