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Supplier: Biotium

Description: CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Supplier: Biotium

Description: CD106 / VCAM1 Monoclonal antibody, Clone: 1.4C3, Host: Mouse, Species: Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Recognizes a protein of 110kDa, Synonyms: CD106, INCAM-100, L1CAM, Vascular cell adhesion protein 1, Application: IF, IHC, Fc, Size: 100ul

Supplier: Biotium

Description: CD27 Monoclonal antibody, Clone: 203.6, Host: Mouse, Species reactivity: Human, Isotype: IgG3, kappa, Conjugate: CF568, Immunogen: Sezary cells, Synonyms: T14, TNFRSF7, TNFSF7, Tp55, Application: IF, FC, Size: 500 uL

Supplier: Biotium

Description: GM-CSF, Monoclonal antibody, Clone: BVD2-21C11, Host: Mouse, Species reactivity: Human, Rhesus monkey, Cynomolgus monkey, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Recombinant human GM-CSF protein, Application: Immunofluorescence, Western, Size: 100uL

Supplier: Biotium

Description: PLAP (Placental Alkaline Phosphatase), Monoclonal antibody, Clone: ALPP/238, Host: Mouse, Species reactivity: Human, Isotype: IgM, kappa, Conjugate: CF488A, Immunogen: Recombinant full-length human ALPP protein, Application: IF, Immunohistology (formalin), Flow, Size: 500uL

Supplier: Biotium

Description: This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Supplier: Biotium

Description: Anti-IgG Donkey Polyclonal Antibody (CF™ 633)

Supplier: Biotium

Description: CD106 / VCAM1 Monoclonal antibody, Clone: VCAM1/843, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Recom human VCAM1 protein, Synonyms: CD106, INCAM-100, L1CAM, Application: IF, IHC, FC, Size: 500 uL

Supplier: Biotium

Description: This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.

Supplier: Biotium

Description: This MAb recognizes a 60 kDa antigen associated with the mitochondria in cells. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. It recognizes an antigen associated with the mitochondria in cells from a wide variety of animals, but not insects and bacteria. It can be used to stain the mitochondria in cell or tissue preparations and can be used as a mitochondrial marker in subcellular fractions. It produces a spaghetti-like pattern in normal and malignant cells and may be used to stain mitochondria of cells in fixed or frozen tissue sections. It can also be used with paraformaldehyde fixed frozen tissue or cell preparations.

Supplier: Biotium

Description: CD79A Monoclonal antibody, Clone: IGA/764, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Recombinant human IGA protein, Application: IF, Immunohistology (formalin), FC, Size: 500 uL

Supplier: Biotium

Description: Kappa Light Chain, Monoclonal antibody, Clone: HP6053 + L1C1, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Purified human Ig kappa chain (HP6053) & Human B-Lymphoma Cells (L1C1), Synonyms: HCAK1, Size: 500uL

Supplier: Biotium

Description: CD8a (clone SK1) is a validated mouse monoclonal antibody that recognizes CD8a, a transmembrane glycoprotein and co-receptor found in T cells. This antibody derived from the CD8 alpha chain. The antibody is available conjugated to CF® Dyes and Astral™ tandem dyes. They are supplied in PBS, 0.1% BSA, 0.05% azide.

Supplier: Biotium

Description: P55;50 EBV-Early Antigen, Monoclonal antibody, Clone: 1108-1, Host: Mouse, Species reactivity: EBV, Isotype: IgG1, kappa, Conjugate: CF640R, Synonyms: EBNA1; EBV nuclear antigen 1; Epstein Barr nuclear antigen 1, Application: Immunofluorescence, Size: 500uL

Supplier: Biotium

Description: This antibody recognizes a 180-185 kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Supplier: Biotium

Description: Protein phosphorylation is a fundamental event in the regulation of a large number of intracellular processes. Phosphorylation of specific tyrosine residues is the result of activation or stimulation of their respective protein tyrosine kinases. The phosphorylated proteins can be auto-phosphorylated kinases or certain cellular protein substrates. Tyrosine-phosphorylated proteins are involved in signal transduction and in the regulation of cell proliferation. Antibody to phosphotyrosine provides an excellent tool for the detection, characterization, and purification of phosphotyrosine containing proteins. This MAb shows no cross-reaction with other phosphoamino acids and is superb for multiple applications including staining of formalin/paraffin tissues.