You Searched For: Hycor Biomedical Ltd

Description: Host: Mouse, Isotype: IgG1

Catalog Number: 89153-178

Supplier: Enzo Life Sciences

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Description: Potent and selective PPARγ antagonist. T0070907 blocks PPARγ function in both cell-based reporter gene and adipocyte differentiation assays. It inhibits growth and survival of hepatocellular carcinoma cells and squamous cell carcinoma cell lines by interfering with cell adhesion "anoikis".

Catalog Number: 89158-802

Supplier: Enzo Life Sciences

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Description: Inhibitor of several ABC-transporters of the subfamily ABCC or MRP (multidrug resistant associated protein).

Catalog Number: 89151-130

Supplier: Enzo Life Sciences

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Description: Recommended Applications: IF, IP, WB

Species reactivity: Eukaryote

Catalog Number: 76002-584

Supplier: Enzo Life Sciences

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Description: Produced in insect cells. Active recombinant human DPP8 with an N-terminal purification tag.

Catalog Number: 89164-460

Supplier: Enzo Life Sciences

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Description: This peptide, KVEKIGEGTYGVVYK, is derived from amino acids 6-20 of cdc2 and is a good substrate for src and other tyrosine kinases.

Catalog Number: 89161-058

Supplier: Enzo Life Sciences

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Description: Host: Mouse, Isotype: IgG3

Catalog Number: 89153-874

Supplier: Enzo Life Sciences

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Description: Host: Rabbit

Catalog Number: 89163-070

Supplier: Enzo Life Sciences

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Description: Mitochondria dye.

Catalog Number: 89166-060

Supplier: Enzo Life Sciences

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Description: The conversion of arachidonic acid to prostaglandin H2 (PGH2) by cyclooxygenase (COX) enzymes is the first step in the synthesis of prostanoids. Prostaglandin D2 (PGD2) is synthesized from PGH2 by the action of PGD synthase, and its actions in vasodilation and platelet activation are mediated via activation of two identified G-protein coupled receptors (GPCRs): DP1 and DP2 (formerly CRTH2). Both DP1 and DP2 receptors are coupled to Gs alpha subunits, resulting in increased adenylyl cyclase activity and cAMP production upon agonist binding. DP1 receptor is expressed moderately in the ileum and weakly in the lung, stomach, and uterus of mice, and weakly in the small intestine of humans. In rodents, expression of PGD synthase and the DP1 receptor is seen in the leptomeninges, where it is believed they play a role in the induction of sleep. The DP1 receptor may also oppose DP2-mediated activation of basophils, eosinophils, and Th2 cells.

Catalog Number: 89141-464

Supplier: Enzo Life Sciences

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Description: Hsp65 is a member of the Hsp60 family of heat shock proteins isolated from Mycobacterium bovis BCG. Hsp65 from M. bovis is identical to that of M. tuberculosis, and similar to that of M. leprae, two highly pathogenic strains of mycobacterium. Hsp65 is the immunodominant antigen during mycobacterial infection and vaccination, and has been linked to the development of autoimmune adjuvant arthritis in rats.

Catalog Number: 89135-226

Supplier: Enzo Life Sciences

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Description: Endogenous lipid which significantly reduced food intake in a dose-dependent fashion when administered to rats and mice (100 mg/kg, i.p.), without causing taste aversion. Has been found to enter the brain (concentrating in the hypothalamus) when administered systemically and also reduced food intake when infused intracerebroventricularly (nanomolar concentrations). This suggests that mediation of effects is via the CNS. Chronic infusion resulted in a reduction of both food intake and body weight.

Catalog Number: 76002-388

Supplier: Enzo Life Sciences

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Description: The Screen-Well Cardiotoxicity Library is a focused collection of 130 compounds with defined and diverse cardiotoxicity, including ion channel blockage, mitochondrial toxicity, arrhythmia, fibrosis, and many more.

Catalog Number: 89426-200

Supplier: Enzo Life Sciences

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Description: MG-132 is a potent, cell permeable and selective proteasome inhibitor (Ki = 4nM).1 It inhibits NF-κB activation by preventing IκB degradation (IC50 = 3μM). The peptide blocks degradation of short-lived proteins, which in turn induces HSP and ER chaperone expression, leading to thermotolerance (1μM MG-132, 2 h.). It also stimulates neurite outgrowth in PC12 cells (20nM optimal). The peptide has also been reported to increase the survival rate of mesenchymal stem cells following their transplantation. IC50’s for inhibition of Suc-LLVY-AMC and Z-LLL-AMC cleaving activities of proteasome were 0.85 and 0.1μM respectively. The ubiquitin-proteasome system (UPS) and autophagy serve as two complementary, reciprocally regulated protein degradation systems, thus blockade of UPS by MG-132 activates autophagy.

Catalog Number: 89161-566

Supplier: Enzo Life Sciences

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Description: Recommended Applications: ELISA, Flow Cytometry, ICC, IF, IHC (PS), IP, WB, Electron microscopy

Catalog Number: 76271-444

Supplier: Enzo Life Sciences

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Description: Selective ligand for toll-like receptor 7 (TLR7) via IFN.

Catalog Number: 89151-598

Supplier: Enzo Life Sciences

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