You Searched For: Willy Kaldenbach KG

Description: Produced in <i>E. coli</i>.

Catalog Number: 89144-410

Supplier: Enzo Life Sciences

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Description: Host: Rabbit

Catalog Number: 89145-204

Supplier: Enzo Life Sciences

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Description: Host: Rabbit

Catalog Number: 89145-636

Supplier: Enzo Life Sciences

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Description: For the measurement of active Rho in cell lysates of human, mouse, and rat origin.

Catalog Number: 89141-848

Supplier: Enzo Life Sciences

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Description: The Carboxyfluorescein Multi-Caspase Activity Kit detects apoptosis through the covalent binding of a green fluorescent probe to active caspase enzymes in living cells.

Catalog Number: 89156-432

Supplier: Enzo Life Sciences

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Description: ACA is a close structural analog of the PLA2 inhibitor, ONO-RS-082 and possesses similar but less potent inhibitory activity. Inhibits TRP channels independently of PLA2, including TRPM2, TRPC6 and TRPM8. It is a useful tool for studying the physiological role of TRP channels.

Catalog Number: 76002-074

Supplier: Enzo Life Sciences

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Description: Naturally occurring mycotoxin produced by many species of <i>Aspergillus</i>. It is metabolised by the liver to the reactive intermediate aflatoxin M1. Exposure may produce acute necrosis, cirrhosis and carcinoma of the liver. Induces DNA damage.

Catalog Number: 89152-978

Supplier: Enzo Life Sciences

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Description: Hepatotoxic and hepatocarcinogenic mycotoxin.

Catalog Number: 89153-028

Supplier: Enzo Life Sciences

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Description: Cytotoxic and enterotoxic

Catalog Number: 89152-986

Supplier: Enzo Life Sciences

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Description: Isolated from Griffonia (Bandeiraea) simplicifolia seeds.

Catalog Number: 89153-052

Supplier: Enzo Life Sciences

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Description: DAPH abolishes or greatly reduces previously existing fully formed β-amyloid (1-42) fibrils and eliminates β-amyloid (1-42) peptide neurotoxicity. Also inhibits EGFR kinase. IC50 for inhibition of β-sheet content of aggregated β-amyloid (1-42) is 4.5µM.

Catalog Number: 89158-238

Supplier: Enzo Life Sciences

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Description: Produced in E. coli

Catalog Number: 89164-224

Supplier: Enzo Life Sciences

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Description: Host: Goat

Catalog Number: 89146-006

Supplier: Enzo Life Sciences

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Description: Host: Goat

Catalog Number: 89146-122

Supplier: Enzo Life Sciences

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Description: Substance P (SP) is an 11 amino acid member of the tachykinin family of neuropeptides which includes SP, neurokinin-A (NK-A) and neurokinin-B (NK-B), all of which exhibit a common COOH-terminal pentapeptide sequence Phe-X-Gly-Leu-Met-NH2. SP functions as a neurotransmitter and its effects are associated with physiological processes such as vomiting, pain, and vasodilation. Three tachykinin receptors have been identified to date, NK1, NK2, and NK3, with SP showing preferential affinity for the NK1 receptor. SP signaling occurs primarily via coupling of Gq/11 alpha subunits to NK1, leading to phospholipase C activation. High SP concentrations may also stimulate adenylyl cyclase activity, resulting in elevated cAMP.

Catalog Number: 89141-466

Supplier: Enzo Life Sciences

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Description: The suppressor of cytokine signaling (SOCS) and cytokine-inducible SH2 proteins are a family of intracellular proteins that regulate the cellular immune response to cytokines. SOCS1 acts to suppress dendritic cell (DC) and T cell hyperactivation in response to cytokine signaling by inhibiting the JAK tyrosine kinase. JAK tyrosine kinase activity is necessary for type I and II cytokine receptors to initiate signaling, and its activity is blocked by direct binding of SOCS1 to the catalytic domain of the kinase. SOCS1 also possesses E3 ubiquitin protein ligase activity that results in the polyubiquitination of its target proteins and subsequent degradation by the proteosome. It is through this method that SOCS1 negatively regulates signaling by Toll-like receptors TLR2 and TLR4 by mediating the degradation of the TLR signaling adaptor protein TIRAP.

Catalog Number: 89141-404

Supplier: Enzo Life Sciences

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