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Image Unavailable-76754-082

Anti-SLC5A5 Rabbit Polyclonal Antibody

Catalog Number: (76754-082)
Supplier: Prosci
Description: Anti-SLC5A5 Rabbit Polyclonal Antibody
Image Unavailable-77130-080

Apcs Peptide

Catalog Number: (77130-080)
Supplier: Prosci
Description: Apcs Peptide
Image Unavailable-77120-654

Anti-PTCH1 Goat Polyclonal Antibody

Catalog Number: (77120-654)
Supplier: Prosci
Description: Anti-PTCH1 Goat Polyclonal Antibody
Product Image-10751-218

Anti-FBXL16 Rabbit Polyclonal Antibody

Catalog Number: (10751-218)
Supplier: Prosci
Description: FBXL16 Antibody: FBXL16 (F-box and leucine-rich repeat protein 16), a member of the F-box protein family, is a probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It is characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F-box, and they interact with ubiquitination targets through other protein interaction domains. FBXL16 is a novel E2F1-regulated gene in crucial cell cycle regulation pathways.
Product Image-10797-498

Human Recombinant IL13 Ra1 (from HEK293 cells)

Catalog Number: (10797-498)
Supplier: Prosci
Description: Interleukin 13 receptor, alpha 1 is also known as IL13RA1, NR4 and CD213A1 (cluster of differentiation 213A1), The IL13 R?1 cDNA encodes a 427 amino acid (aa) residue precursor protein with a putative 21 aa residue signal peptide, a 324 aa residue extracellular domain, a 23 aa residue transmembrane region and a 59 aa residue cytoplasmic tail. Human and mouseIL13R?1 share 76% aa sequence identity. IL13RA1 is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
Product Image-10103-990

Anti-CCDC138 Rabbit Polyclonal Antibody

Catalog Number: (10103-990)
Supplier: Prosci
Description: The function of the CCDC138 protein remains unknown.
Product Image-10110-844

Anti-LCA5 Rabbit Polyclonal Antibody

Catalog Number: (10110-844)
Supplier: Prosci
Description: LCA5 is a protein that is thought to be involved in centrosomal or ciliary functions. Mutations in this gene cause Leber congenital amaurosis type V. This gene encodes a protein that is thought to be involved in centrosomal or ciliary functions. Mutations in this gene cause Leber congenital amaurosis type V. Alternative splicing results in two transcript variants.
Product Image-10109-338

Anti-GPNMB Rabbit Polyclonal Antibody

Catalog Number: (10109-338)
Supplier: Prosci
Description: GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential.The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Product Image-10749-560

Anti-CASP12 Rabbit Polyclonal Antibody

Catalog Number: (10749-560)
Supplier: Prosci
Description: Caspase-12 Antibody: (Large)Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the main, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.
Image Unavailable-75789-684

Human Recombinant AMIGO2 (from Cells)

Catalog Number: (75789-684)
Supplier: Prosci
Description: Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, a LRRCT domain, as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast, ovary, cervix, and uterus, although lower in lung, colon, and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. AMIGO2 may contribute to signal transduction through its intracellular domain, and may be required for tumorigenesis of a subset of gastric adenocarcinomas.
Image Unavailable-75791-650

Human Recombinant IL-12 R beta1 (from Cells)

Catalog Number: (75791-650)
Supplier: Prosci
Description: Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL12 with only low affinity. IL12 high affinity receptor complex is composed of two subunits designated IL12RB1 and IL12RB2. While IL12RB1 interacts with the IL-12p40 subunit, IL-12p35 is mainly connecting with IL12RB2. This receptor chain is also responsible for transmitting the IL12 signal into the cell. IL12RB1, to the contrary, is also part of the IL23R, where it interacts with the p40 subunit of IL23. IL12RB1 is expressed in activated T cells, NK cells and B cells.
Product Image-10113-150

Anti-PGBD1 Goat Polyclonal Antibody

Catalog Number: (10113-150)
Supplier: Prosci
Description: Polyclonal, Host: Goat, Species Reactivity: Human, Immunogen: PGBD1 antibody was raised against a 12 amino acid synthetic peptide near the internal region of PGBD1, Tested Applications: ELISA, WB, IHC
Product Image-10112-274

Anti-STAT3 Goat Polyclonal Antibody

Catalog Number: (10112-274)
Supplier: Prosci
Description: Polyclonal, Host: Goat, Species: Mouse, Immunogen: STAT3 antibody was raised against a 13 amino acid synthetic peptide near the C-Terminus of STAT3, Application: ELISA, WB, IHC
Image Unavailable-77120-132

KEO4/ERLIN1 Peptide

Catalog Number: (77120-132)
Supplier: Prosci
Description: KEO4/ERLIN1 Peptide
Image Unavailable-77121-596

Anti-Klrc1 Rat Monoclonal Antibody [clone: [20d5]] (Biotinylated)

Catalog Number: (77121-596)
Supplier: Prosci
Description: Anti-Klrc1 Rat Monoclonal Antibody [clone: [20d5]] (Biotinylated)
Product Image-10105-292

Anti-NR5A2 Rabbit Polyclonal Antibody

Catalog Number: (10105-292)
Supplier: Prosci
Description: NR5A2 binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. It may be responsable for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. It is a key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. It may also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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