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Product Image-10108-070

Anti-PCBP2 Rabbit Polyclonal Antibody

Catalog Number: (10108-070)
Supplier: Prosci
Description: PCBP2 appears to be multifunctional. It along with PCBP-1 and hnRNPK corresponds to the major cellular poly (rC)-binding proteins. This protein together with PCBP-1 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This gene and PCBP-1 has paralogues PCBP3 and PCBP4 which is thought to arose as a result of duplication events of entire genes.The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly (rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.
Image Unavailable-10072-994

Human Recombinant GCP-2 (from E. coli)

Catalog Number: (10072-994)
Supplier: Prosci
Description: Human GCP-2 is a member of the CXC family of chemokines. It also promotes neutrophil chemotaxis and degranulation. Recombinant Human GCP-2 is an 7.9 kDa protein containing 72 amino acid residues.
Image Unavailable-77119-206

TGM3 Peptide

Catalog Number: (77119-206)
Supplier: Prosci
Description: TGM3 Peptide
Image Unavailable-76752-214

Anti-RALA Rabbit Polyclonal Antibody

Catalog Number: (76752-214)
Supplier: Prosci
Description: Anti-RALA Rabbit Polyclonal Antibody
Image Unavailable-77124-554

SWAP70 Peptide

Catalog Number: (77124-554)
Supplier: Prosci
Description: SWAP70 Peptide
Image Unavailable-77129-400

MDM2 Peptide

Catalog Number: (77129-400)
Supplier: Prosci
Description: MDM2 Peptide
Image Unavailable-77123-460

ALS2CR3 Peptide

Catalog Number: (77123-460)
Supplier: Prosci
Description: ALS2CR3 Peptide
Image Unavailable-76757-682

Anti-ARPC5 Rabbit Polyclonal Antibody

Catalog Number: (76757-682)
Supplier: Prosci
Description: Anti-ARPC5 Rabbit Polyclonal Antibody
Image Unavailable-77131-506

CHRNA7 Peptide

Catalog Number: (77131-506)
Supplier: Prosci
Description: CHRNA7 Peptide
Image Unavailable-77128-768

Anti-Ptprc Rat Monoclonal Antibody [clone: [C363.16A]] (FITC (Fluorescein Isothiocyanate))

Catalog Number: (77128-768)
Supplier: Prosci
Description: Anti-Ptprc Rat Monoclonal Antibody [clone: [C363.16A]] (FITC (Fluorescein Isothiocyanate))
Image Unavailable-77125-450

Human, Mouse, Rat Recombinant Irisin Protein (from CHO cells)

Catalog Number: (77125-450)
Supplier: Prosci
Description: Human, Mouse, Rat Recombinant Irisin Protein (from CHO cells)
Image Unavailable-75791-146

Human Recombinant FKBP25 (from E. coli)

Catalog Number: (75791-146)
Supplier: Prosci
Description: FKBP3 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Product Image-10751-668

Anti-TET2 Rabbit Polyclonal Antibody

Catalog Number: (10751-668)
Supplier: Prosci
Description: TET2 Antibody: TET2, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. It is a candidate tumor suppressor gene reported to be mutated in approximately 14% of patients with JAK2V617F-positive myeloproliferative neoplasms, and can be mutated in other hematopoietic disorders such as myelodysplastic syndromes, acute myeloid leukemia, and chronic myelomonocytic leukemia. Analysis of the TET2 and JAK2 mutations in these neoplasms suggests that mutations in TET2 do not represent a predisposition for acquiring mutations in JAK2.
Product Image-10764-394

Anti-CD4 Rat Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: GK1.5]

Catalog Number: (10764-394)
Supplier: Prosci
Description: The GK1.5 monoclonal antibody specifically binds with the mouse CD4 molecule, also known as L3T4, a 55 kDa differentiation antigen which binds to the MHC class II. CD4 is expressed on most thymocytes, a subpopulation of mature T lymphocytes, dendritic cells, pluripotent hematopoietic stem cells, B cell precursors, and lymphoid precursors inside the thymus. It is also expressed on the mouse egg cell membrane, enhancing adhesion to MHC class II bearing sperm. By interaction with MHC class II on the surface of APC, CD4 initiates the development of T lymphocytes and helps the optimum functioning of mature T lymphocytes. The binding of the GK1.5 antibody blocks the binding of the Anti-Mouse CD4 RM4-5 antibody.
Product Image-10114-372

Anti-SON Goat Polyclonal Antibody

Catalog Number: (10114-372)
Supplier: Prosci
Description: Polyclonal, Host: Goat; Target Species: Human, Mouse, Rat; Immunogen: SON antibody was raised against a 13 amino acid synthetic peptide near the N-Terminus of SON; Applications: ELISA,Western blotting
Image Unavailable-76755-828

Anti-TMED3 Rabbit Polyclonal Antibody

Catalog Number: (76755-828)
Supplier: Prosci
Description: Anti-TMED3 Rabbit Polyclonal Antibody
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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