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Catalog Number: (10099-584)
Supplier: Prosci
Description: GATA6 is thought to be important for regulating terminal differentiation and/or proliferation.


Catalog Number: (10104-856)
Supplier: Prosci
Description: EBF1 belongs to the COE family. It contains 1 IPT/TIG domain. EBF1 is a transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.


Catalog Number: (10107-722)
Supplier: Prosci
Description: RFX4 is a transcription factors that contain a highly-conserved winged helix DNA binding domain. RFX4 is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. RFX4 may be a transcriptional repressor rather than a transcriptional activator.This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. This protein may be a transcriptional repressor rather than a transcriptional activator. Three transcript variants encoding different isoforms have been described for this gene.This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. This protein may be a transcriptional repressor rather than a transcriptional activator. Three transcript variants encoding different isoforms have been described for this gene.


Catalog Number: (10750-020)
Supplier: Prosci
Description: Grik1 Antibody: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik1, also known as glutamate receptor 5, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik1 is expressed in GABAergic interneurons of the hippocampus and are thought to participate in the formation of various subtypes of kainate receptors with Grik2 and KA2. Stimulation of Grik1 leads to intracellular calcium release and activation of protein kinase C. Excessive activation has been associated with psychiatric, neurological and neurodegenerative diseases. Numerous isoforms of Grik1 are known to exist and may be subject to RNA editing within the second transmembrane domain, which is thought to alter the properties of ion flow.


Catalog Number: (10073-018)
Supplier: Prosci
Description: Chemerin is a secreted chemoattractant protein that can signal through the chemokine like receptor-1 (CMKLR1). It is expressed in various tissues, including white adipose tissue, and circulates in blood as an inactive 143 amino acid precursor protein. Biologically active Chemerin is generated by proteolytic removal of C-terminal residues by several circulating proteases. Chemerin acts as a chemoattractant for cells expressing the CMKLR1 receptor, which includes certain dendritic cells, macrophages, and adipocytes. Recombinant human Chemerin is a 15.6 kDa protein consisting of 135 amino acid residues.


Catalog Number: (10099-944)
Supplier: Prosci
Description: ChGn transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). This protein is required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. It play an important role in chondroitin chain biosynthesis in cartilage.


Catalog Number: (75788-880)
Supplier: Prosci
Description: Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83% sequence identity in their mature regions.


Catalog Number: (75793-250)
Supplier: Prosci
Description: Pyrin regulates inflammation by interacting with the cytoskeleton. Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed. Defects in pyrin are the cause for Mediterranean fever.


Catalog Number: (10116-210)
Supplier: Prosci
Description: Polyclonal antibody KU70 Host: Goat Target Species: human immunogen: KU70 antibody was raised against a 13 amino acid synthetic peptide near the N-Terminus of KU70. Application: ELISA, WB, IF


Catalog Number: (10115-788)
Supplier: Prosci
Description: Polyclonal antibody CNBP Host: Goat Target Species: human immunogen: CNBP antibody was raised against a 13 amino acid synthetic peptide near the C-Terminus of CNBP Application: ELISA, WB


Catalog Number: (10766-498)
Supplier: Prosci
Description: The OKT8 monoclonal antibody specifically reacts with human CD8alpha molecule, a type I transmembrane glycoprotein of 32-34 kDa. CD8 alpha is a member of the Ig superfamily, expressed as a homodimer (CD8 alpha alpha) or as a heterodimer (CD8 alpha beta). CD8+ alpha beta T lymphocytes express both CD8 alpha alpha and CD8 alpha beta, while some T lymphocytes and the natural killer cells express only the homodimers. CD8 binds to MHC class I and influences the development and the activation of T lymphocytes. OKT8, RPA-T8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitoPEor block each other by steric hindrance.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.


Catalog Number: (10114-884)
Supplier: Prosci
Description: Polyclonal, Host: Goat; Target Species: Human; Immunogen: RAPSN antibody was raised against a 15 amino acid synthetic peptide near the N-Terminus of RAPSN; Applications: ELISA,Western blotting


Catalog Number: (76752-452)
Supplier: Prosci
Description: Anti-DCN Rabbit Polyclonal Antibody


Catalog Number: (76759-910)
Supplier: Prosci
Description: Anti-HMGA1 Rabbit Polyclonal Antibody


Catalog Number: (77128-522)
Supplier: Prosci
Description: Human Recombinant ApolipoProtein E/APOE Protein (from HEK293 cells)


Catalog Number: (77120-530)
Supplier: Prosci
Description: LCK Peptide


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