You Searched For: PROSCI INCORPORATED

Catalog Number: (89421-020)

Supplier: Prosci

Description: GEMC1 peptide is used for blocking the activity of GEMC1 antibody.

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Catalog Number: (10070-216)

Supplier: Prosci

Description: General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates insulin-stimulated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. Promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase.

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Catalog Number: (76763-906)

Supplier: Prosci

Description: Anti-ARF5 Rabbit Polyclonal Antibody

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Catalog Number: (10068-724)

Supplier: Prosci

Description: Inhibits the activity of dimeric NF-κ-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription.

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Catalog Number: (10101-842)

Supplier: Prosci

Description: ZNF193 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 5 C2H2-type zinc fingers and 1 SCAN box domain. ZNF193 may be involved in transcriptional regulation.

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Catalog Number: (89417-974)

Supplier: Prosci

Description: ECRG2 Antibody: The esophageal cancer-susceptibility gene 2 (ECRG2), also known as SPINK7, is a novel tumor suppressor gene identified from the human esophagus. It interacts directly with metallothionein 2A and urokinase-type plasminogen activator (uPA), and downregulates the activity of uPA, leading to reduced cancer cell migration, invasion and metastasis. ECRG2 forms a complex with uPA and its receptor uPAR, modifying the dynamic association of uPAR with beta1 integrins and disrupting the Src/MAP kinase pathway that normally stimulates cell migration and invasion. ECRG2 may thus represent a novel therapeutic target for cancer.

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Catalog Number: (76012-282)

Supplier: Prosci

Description: This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes.

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Catalog Number: (76764-314)

Supplier: Prosci

Description: Anti-pan Kac (methylated) Rabbit Polyclonal Antibody

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Catalog Number: (10070-834)

Supplier: Prosci

Description: Polyclonal antibody Toxoplasma gondii-FITC Host: Rabbit Species reactivity: Parasite Tested application: WB immunogen RH strain of T. gondii

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Catalog Number: (76762-296)

Supplier: Prosci

Description: Anti-CAN-04 Recombinant Antibody

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Catalog Number: (76011-848)

Supplier: Prosci

Description: For WB starting dilution is: 1:500

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Catalog Number: (10104-984)

Supplier: Prosci

Description: BARHL2 and BARHL1 are two homeobox genes in mouse and human, which are highly related to the Bar Drosophila genes.

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Catalog Number: (10077-986)

Supplier: Prosci

Description: 5-HT7 Receptor is a Serotonin Receptor with several functions, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and GI tract. This receptor has been implicated in depression, autistism, and other neuropsychiatric disorders. Three protein isoforms have been documented: isoform a: 445aa; isoform b: 432aa; isoform d: 479aa.

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Catalog Number: (10751-760)

Supplier: Prosci

Description: KEAP1 Antibody: KEAP1 (kelch-like ECH-associated protein 1) is a stress sensing adaptor for the Cullin3 (Cul3)-dependent E3 ubiquitin ligase complex that negatively regulates NRF2 (NF-E2-related factor 2) and plays a role in the oxidative stress response. It targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome. KEAP1 contains an amino terminal BTB/POZ domain and a carboxyl terminal KELCH domain which are required for interaction with NRF2, and in binding Cul3-E3 ubiquitin ligase. Altered expression of NRF2 is associated with chronic obstructive pulmonary disease (COPD). KEAP1 also targets the down regulation of NF-kappa B activity by targeting IKKbeta ; degradation. Mutation of the KEAP1 gene is found in lung cancer.

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Catalog Number: (89419-540)

Supplier: Prosci

Description: LGP2 peptide is used for blocking the activity of LGP2 antibody.

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Catalog Number: (76748-810)

Supplier: Prosci

Description: Anti-ATXN1 Rabbit Polyclonal Antibody

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