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6,7-Diethoxy-4-(trifluoromethyl) coumarin ≥95% (by HPLC)

Supplier: Adipogen
Description: Fluorescent labelling.

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JC-10 ≥98% (by HPLC)

Supplier: Adipogen
Description: Derivative of JC-1 useful for determining mitochondrial membrane potential by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. Accumulates in mitochondria, selectively generating an orange J-aggregate emission profile (570 nm) in healthy cells. Upon cell injury, as membrane potential decreases, JC-10 monomers are generated, resulting in a shift to green emission (520 nm). Shows improved solubility compared to JC-1 in aqueous media and an ability to detect subtler changes in mitochondrial membrane potential loss. Spectral data: lambdaex 510 nm| lambdaem 525.

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Human Recombinant DLK1 (from HEK293 Cells)

Catalog Number: (102515-164)
Supplier: Adipogen
Description: The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.

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Anti-CD53 Monoclonal Antibody (R-PE) [clone: 63.5A3]

Catalog Number: (102512-438)
Supplier: Adipogen
Description: Human CD53 is a tetraspan cell surface glycoprotein found on all hemopoetic cells except platelets and red blood cells.

Small Business Enterprise


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Anti-IgA Monoclonal Antibody [clone: Hisa43]

Catalog Number: (102511-798)
Supplier: Adipogen
Description: Human immunoglobulins are glycoproteins composed of two disulfide-bonded heavy (H) chain subunits, each of which is linked by interchain disulfide bonds to a light (L) chain forming a tetramolecular complex. There are five classes of immunoglobulins, designated IgG, IgA, IgM, IgD and IgE, which are defined by differences in the constant region of H chains. L chains are divided into kappa or lambda classifications based on structural antigenic differences. All classes of immunoglobulins have been found on the cell surface of B lymphocytes where they function as antigen receptors to elicit antigen-dependent proliferation and secretion of antigen specific soluble circulating antibodies.

Small Business Enterprise


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Anti-CD45RO Monoclonal Antibody [clone: UCHL1]

Catalog Number: (102512-352)
Supplier: Adipogen
Description: Human CD45 is expressed on all cells of hematopoietic origin, except erythrocytes. CD45 is a transmembrane tyrosine phosphatase which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing of exons 4-7 of a single gene coding for the various N-terminal peptide segments. The CD45RO isoform contains none of the alternatively spliced exons and is present on most thymocytes, a subpopulation of resting (memory) T cells within both CD4 and CD8 subsets as well as on monocytes and granulocytes. CD45RO plays an essential role in lymphocyte activation.

Small Business Enterprise


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Anti-CD14 Monoclonal Antibody (Biotin) [clone: UCHM1]

Catalog Number: (102512-048)
Supplier: Adipogen
Description: Human CD14 is strongly expressed on myelomonocyte lineage cells including monocytes, macrophages and a subset of granulocytes. CD14 is a high affinity receptor for complexes of lipopolysaccharide and lipopolysaccharide binding protein. A soluble form of CD14 also binds to LPS and LBP.

Small Business Enterprise


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Mouse Recombinant PEDF (from CHO Cells)

Supplier: Adipogen
Description: Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.

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Anti-PARP-1 Rabbit Polyclonal Antibody

Catalog Number: (102979-952)
Supplier: Adipogen
Description: PARP-1 (ARTD1) is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARP-1 positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. It forms a complex with EEF1A1 and TXK that acts as a T-helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
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Water, distilled

Supplier: Adipogen
Description: DdWater Endotoxin-free (sterile), Endotoxin Content: <0.0002EU/ug, after repeated purification cycles over activated charcoal, Synonyms double-distilled Water, Synonyms double-distilled Water, Short/Long Term Storage: +4 deg C, Size: 3x10ml

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XL388 ≥95%

Supplier: Adipogen
Description: XL388 is a novel class of highly potent, selective, ATP-competitive, and orally bioavailable inhibitors of the mammalian target of rapamycin (mTOR) with an IC(50) of 9.9nM.

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Regorafenib ≥95%

Supplier: Adipogen
Description: Regorafenib (BAY 73-4506, Fluoro-Sorafenib) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFR, Kit, RET and Raf-1 with IC(50) values of 13, 4.2, 46, 22, 7, 1.5 and 2.5nM, respectively.

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Papaverine Hydrochloride

Supplier: Adipogen
Description: Smooth muscle relaxant and vasodilator. Phosphodiesterase PDE10A inhibitor. Antiviral. Antipsychotic. Potential inducer of browning in WAT.

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N-(3-Oxohexadecanoyl)-DL-homoserine lactone ≥97% (by GC)

Supplier: Adipogen
Description: N-(3-Oxohexadecanoyl)-DL-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.

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Afatinib ≥95%

Supplier: Adipogen
Description: Afatinib is an irreversible kinase inhibitor and binds to the kinase domains of EGFR (ErbB1), HER2 (ErbB2), and HER4 (ErbB4) to inhibit tyrosine kinase autophosphorylation. This results in a downregulation of ErbB signaling and subsequent inhibition of proliferation of cell lines expressing wild-type EGFR, selected EGFR exon 19 deletion mutations, or exon 21 L858R mutations. It also inhibited in vitro proliferation of cell lines overexpressing HER2. Overall, tumor growth was inhibited by Afatinib very effectively with low nanomolar IC(50) values ranging from approximately 6nM to below 500nM.

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Tandutinib ≥95%

Supplier: Adipogen
Description: Tandutinib inhibits the auto-phosphorylation of FLT3 (FMS-Like Tyrosine kinase-3, IC(50) of 0.22µM), c-KIT and PDGF (platelet-derived growth factor), thereby inhibiting cellular proliferation and inducing apoptosis.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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  • State issued document with your organization's Federal Tax ID Number
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The original product is no longer available. The replacement shown is available.
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