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Anomalin A ≥97% (by HPLC)

Catalog Number: (102515-676)
Supplier: Adipogen
Description: Lck (p56lck; lymphocyte specific tyrosine kinase) inhibitor. Antioxidant. DPPH radical scavenger.

Small Business Enterprise


Image Unavailable-102515-788

Latrunculin B ≥96% (by HPLC)

Catalog Number: (102515-788)
Supplier: Adipogen
Description: Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Depolymerizes actin filaments (F-actin). Less potent than Latrunculin A. May have fewer unwanted effects than latrunculin A and may be preferred for short-term studies. Acts via a different mechanism than cytochalasins.

Small Business Enterprise


Image Unavailable-102511-422

Anti-alpha-Tubulin Human Antibody (ATTO 488) [clone: F2C]

Catalog Number: (102511-422)
Supplier: Adipogen
Description: Tubulin is the major building block of microtubules. This intracellular cylindrical filamentous structure is present in almost all eukaryotic cells. Microtubules function as structural and mobile elements in mitosis, intracellular transport, flagellar movement, and the cytoskeleton.
Image Unavailable-102971-630

Anti-IL-38 Monoclonal Antibody [clone: Nhat-1]

Catalog Number: (102971-630)
Supplier: Adipogen
Description: IL-38 (IL-1F10) belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 as a IL-1 family receptor antagonist. Il-38 inhibits IL-36 signaling by binding to IL-1R6. IL-38 (aa 20-152) is released from apoptotic cells to limit inflammatory macrophage and downstream Th17 activation by blocking IL1RAPL1 (Interleukin-1 receptor accessory protein-like 1, TIGIRR-2) signaling. IL-38 is unregulated during some autoimmune diseases such as Systemic Lupus Erythematosus.
Image Unavailable-102513-172

Anti-CD45RA Monoclonal Antibody (Biotin) [clone: 158.4D3]

Catalog Number: (102513-172)
Supplier: Adipogen
Description: Human CD45RA is expressed on all cells of hematopoietic origin, except erythrocytes. CD45RA is a transmembrane tyrosine phosphate which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing of exons 4-7 of a single gene coding for the various N-terminal peptide segments. The CD45RA isoform predominates on naive/resting T cells and medullary thymocytes.

Small Business Enterprise


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Anti-FLIP Monoclonal Antibody [clone: NF6]

Supplier: Adipogen
Description: FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells and acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. FLIP lacks enzymatic (caspase) activity. FLIP is highly expressed in skeletal muscle, pancreas, heart, kidney, placenta and peripheral blood leukocytes.

Image Unavailable-102991-036

Thiazole orange ≥98% (by HPLC)

Supplier: Adipogen
Description: Thiazol Orange is a nucleic acid stain that has found applications in many different areas. Among others it is used for reticulocyte analysis and Plasmodium species analysis as well as labeling cancer cells. Thiazole orange-labeled DNA has been used for live cell RNA imaging. Thiazole Orange has also been used for a variety of assays, PCR and flow cytometry.

Image Unavailable-102987-944

FITC (fluorescein-5-isothiocyanate, fluorescein isothiocyanate isomer I)

Supplier: Adipogen
Description: Fluorescent marker for biochemical applications. Reacts under mild conditions with primary amines. Used in modification of actin at lys-61, labelling of FAB and the modification of thiol groups.

Image Unavailable-102987-912

7-Fluorobenzo-2-oxa-13-diazole-4-sulfonic acid ammonium salt

Supplier: Adipogen
Description: Fluorescent probe for thiols widely used in pre-column labeling of biological thiols for HPLC.

Image Unavailable-102992-266

JNJ-38158471 ≥95%

Supplier: Adipogen
Description: JNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with an IC(50) of 40nM. It also inhibits closely related tyrosine kinases such as Ret (IC(50) of 180nM) and Kit (C50 of 500nM). It has no significant activity (<gt/>1µM) against VEGFR-1 and VEGFR-3.

Image Unavailable-102989-320

8-Butyryloxy-pyren-1,3,6-trisulfonic acid ≥95% (by HPLC)

Supplier: Adipogen
Description: Highly water soluble enzyme substrate for the fluorimetric assay of esterases at longwave excitation and emission wavelengths.

Image Unavailable-102989-580

2-(Chloromethyl)benzoic acid

Supplier: Adipogen
Description: Building block for synthesis.

Image Unavailable-102513-548

Chrysomycin A (from Streptomyces species) ≥98% (by HPLC)

Supplier: Adipogen
Description: Chrysomycin A is a Topoisomerase II inhibitor.

Small Business Enterprise

Image Unavailable-102512-692

Anti-CD62L Monoclonal Antibody (APC) [clone: LAM1-116]

Catalog Number: (102512-692)
Supplier: Adipogen
Description: Human CD62L is as adhesion molecule found on most leukocytes and plays a primary role in mediating initial leukocyte interaction with activated vascular endothelium. Human CD62L has signal transduction functions where engagement leads to increased calcium levels and upregulated expression of certain integrins.

Small Business Enterprise


Image Unavailable-102981-258

ZnAF-1 DA ≥90% (by HPCE)

Supplier: Adipogen
Description: Suitable for the fluorimetric detection of Zn2+ (after esterase hydrolysis). Spectral data: lambdaex 492nm; lambdaem 515nm in PBS.

Image Unavailable-102989-156

5(6)-Aminofluorescein (Mixture of isomers) ≥95% (by HPLC)

Supplier: Adipogen
Description: Two isomers are produced by the usual synthesis. Most publications imply they are interchangeable when used for the preparation of the isothiocyanate for fluorescent labeling.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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