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6-HEX dipivaloate ≥98% (by HPLC)

Supplier: Adipogen
Description: 6-HEX is an amino-conjugatable fluorescent probe that is widely used in nucleic acid sequencing and related research. It can also be used to label peptides and oligonucleotides.

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AK-7 ≥98% (by NMR)

Supplier: Adipogen
Description: Brain-permeable SIRT2 (sirtuin 2) inhibitor.

Small Business Enterprise

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Anti-BAFF Rat Monoclonal Antibody [clone: 4.62]

Catalog Number: (102514-290)
Supplier: Adipogen
Description: BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren's syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).
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Human Recombinant Vaspin (from HEK293 Cells)

Supplier: Adipogen
Description: Vaspin (Visceral adipose tissue-derived serpin; Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both visceral and subcutaneous white adipose tissue. Based on recent findings, vaspin is suggested to regulate immune responses and inflammation and was found to be correlated with various metabolic parameters. Vaspin may represent a novel biomarker for obesity and impaired insulin sensitivity and might serve as a new therapeutic target of metabolic syndrome.

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Gilvocarcin V (from Streptomyces sp. Gö 3592) ≥98% (by HPLC)

Supplier: Adipogen
Description: Gilvocarcin V is an antibiotic, anti-tumor compound.

Small Business Enterprise

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GSK429286A ≥95%

Supplier: Adipogen
Description: GSK429286A is a potent and selective inhibitor of Rho-associated kinase (ROCK1), with an IC(50) of 14nM. It is orally available and has been shown to dramatically reduce mean arterial pressure in spontaneously hypertensive rats.

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Nω-Methyl-L-arginine monoacetate ≥99% (by TLC)

Supplier: Adipogen
Description: Endothelium-derived relaxing factor inhibitor. Inhibits the generation of NO from arginine. Competitive, irreversible non-selective inhibitor of all three NOS I, II, and III isoforms (eNOS, iNOS and nNOS). Inhibits the synthesis of nitric oxide (NO) in a dose-dependent and enantiospecific fashion. Useful tool to study the role and the effects of NO in cardiovascular and gastrointestinal disorders, hypertension, diabetes, septic shock, inflammation, infection, stroke and neurodegenerative disorders.

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7-Amino-4-methyl-3-coumarinylacetic acid (AMCA-H) ≥90% (by HPLC)

Supplier: Adipogen
Description: AMCA is one of the brightest amine-reactive blue fluorescent dyes useful for immunofluorescence and fluorescent labeling (Ex/Em: 353/455nm). It is quite photostable, and its fluorescence is pH-independent from pH 4 to 10. The properties include a relatively large Stoke's shift and resistance to photobleaching. Reactive AMCA derivatives are used as contrasting probes for double and triple labeling in immunofluorescence microscopy, arrays and in situ hybridization.

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n-Dodecyl-β-D-maltoside, Ultrapure

Supplier: Adipogen
Description: Non-ionic detergent. For functional solubilization, purification and crystallography of membrane proteins. For the stabilization and activation of enzymes.

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3-Hydroxy-hexanoyl-DL-homoserine lactone ≥98% (by NMR)

Supplier: Adipogen
Description: 3-Hydroxy-hexanoyl-DL-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.

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Smoothened Agonist ≥98% (by NMR)

Supplier: Adipogen
Description: Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro.

Small Business Enterprise

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2,3,3-Trimethyl-1-(4-sulfobutyl)-indolium, inner salt ≥98% (by HPLC)

Supplier: Adipogen
Description: Building block for synthesis. Reagent used for electrophilic phenylation, e.g. of malonates and dithiocarboxylates.

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Anti-NQO1 Mouse Monoclonal Antibody [clone: Skiny-1]

Supplier: Adipogen
Description: NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body's protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer's disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.

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alpha-NETA ≥97% (by NMR)

Supplier: Adipogen
Description: Potent fluorescent inhibitor of choline acetyltransferase. CMKLR1 antagonist. Inhibits chemerin-stimulated beta-arrestin2 association with CMKLR1, as well as chemerin-triggered CMKLR1+ cell migration. Aldehyde dehydrogenase 1 (ALDH1A1) antagonist.

Small Business Enterprise

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4-Methylumbelliferyl Butyrate

Supplier: Adipogen
Description: Fluorogenic substrate for butyrate esterase.

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Mouse Recombinant IL-33R (from CHO Cells)

Catalog Number: (103691-930)
Supplier: Adipogen
Description: Receptor for interleukin-33 (IL-33). Its stimulation recruits MYD88, IRAK1, IRAK4 and TRAF6 followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14 and MAPK8 by similarity. Possibly involved in helper T cell function.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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