You Searched For: Strobilurin B

Description: Human CD14 is strongly expressed on myelomonocyte lineage cells including monocytes, macrophages and a subset of granulocytes. CD14 is a high affinity receptor for complexes of lipopolysaccharide and lipopolysaccharide binding protein. A soluble form of CD14 also binds to LPS and LBP.

Catalog Number: 102512-052

Supplier: Adipogen

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Description: Shows strong gastrointestinal motor stimulating (GMS) activity. Motilin receptor agonist. Stimulates smooth muscle cell contraction. Stimulates cholinergic neurons in a non-vagal pathway. Enhances gastrointestinal contractile activity and accelerates gastric emptying. Shows orexigenic activity with affinity for the growth-hormone secretagogue receptor (GHS-R, ghrelin receptor).

Catalog Number: 102987-344

Supplier: Adipogen

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Description: Building block for synthesis.

Catalog Number: 102991-132

Supplier: Adipogen

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Description: NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body's protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer's disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.

Catalog Number: 102514-620

Supplier: Adipogen

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Description: Semi-synthetic derivative of artemisinin. Anti-malaria. Anti-schistosomiasis. Inhibitor of human cytomegalovirus (CMV). Apoptosis inducer. Anti-cancer. Immunosuppressant. Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO).

Catalog Number: 102988-386

Supplier: Adipogen

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Description: N-Decanoyl-L-homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. The applications of this molecule include regulation of virulence and exoproteases.

Catalog Number: 102989-784

Supplier: Adipogen

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Description: Fluorescent probe for detection of H2S2 and hydrogen polysulfides in aqueous buffers.

Catalog Number: 102989-808

Supplier: Adipogen

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Description: TDO incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin.

Catalog Number: 102514-622

Supplier: Adipogen

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Description: Cell/membrane permeable, non-toxic, pH-sensitive fluorescent dye (blue-green range) for live imaging of pH alteration in acidic organelles, lysosomes, autophagolysosomes, vesicles, cells, tissue and even small, transparent whole animals without side effects. Useful as intracellular pH indicator with a wide range of fluorescence (pH 3 to pH 13). pH-dependent dual-emission peaks, can be used for ratiometric evaluation of pH (F400/440). No esterases are involved, therefore no toxic by-products occur. Long-term stable; is barely metabolized. Fluorescence co-localizes with LysoTracker® Red DND-99. (LysoTracker® is a registered trademark of Molecular Probes, Inc.)

Catalog Number: 102981-162

Supplier: Adipogen

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Description: Fumitremorgin-type alkaloid. Tremorgenic neurotoxic mycotoxin. Selective blocker of KCa1.1 (high-conductance Ca2+-activated K+; BK; maxi-K) channels. Decreases GABA levels in CNS. Increases spontaneous glutamate and aspartate release. At toxic doses, increases the number and decreases the affinity of DHP receptors in rat cortex. Cell cycle inhibitor at the M phase. Inhibits calmodulin and PKC activity. Has apoptotic effects on human T lymphocytes. Stimulates the growth of seedling roots of buckwheat.

Catalog Number: 102989-038

Supplier: Adipogen

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Description: RpS3 is a component of the 40S ribosomal subunit and is an an essential but previously unkown subunit of NF-kappaB involved in the regulation of key genes in rapid cellular activation responses. RpS3 interacts with nm23-H1. The expression of rpS3 reduces the secretion of MMP-9 and the invasive metastatic potential in HT1080 cells. The phosphorylated ERK is reduced by the expression of rpS3.

Catalog Number: 102514-102

Supplier: Adipogen

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Description: Anti-cancer compound. Cell synchronization agent. Used as a drug in chemotherapy by synchronizing tumor cells at metaphase, the radiosensitive stage of the cell cycle. Microtubule assembly inhibitor. Depolymerizes microtubules and limits microtubule formation (inactivates spindle fibre formation). Inhibits mitosis during cell division at metaphase by inhibiting spindle formation. Low concentrations affect microtubule dynamics and cell migration, while high concentrations promote microtubule detachment from microtubule organizing center. Apoptosis inducer. Thrombopoietic agent.

Catalog Number: 102516-304

Supplier: Adipogen

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Description: Human CD165 is a cell surface molecule present on a subset of peripheral lymphocytes and monocytes and is important for adhesion of thymocytes to thymic epithelial cells.

Catalog Number: 102513-150

Supplier: Adipogen

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Description: Human CD35 binds complement components C3b, C4b and iC3b and is expressed on erythrocytes, B cells, monocytes, granulocytes and folicular dendritic cells and on subsets of thymocytes. CD35 on erythrocytes mediates clearance of immune complexes.

Catalog Number: 102512-270

Supplier: Adipogen

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Description: Potent and selective PPARgamma agonist with no activation of PPARalpha and PPARdelta. Anti-diabetic agent with potent glucose-lowering effects and decreasing insulin resistance in adipose tissues. Stimulates adipogenesis. Apoptosis and cell cycle arrest inducer in several cancer cell lines. Anti-inflammatory. Inhibits vascular smooth muscle cell (VSMC) migration.

Catalog Number: 102516-294

Supplier: Adipogen

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Description: Major metabolite of pentoxifylline. Most effective metabolite at reducing oxygen radical production by polymorphonuclear leukocytes (PMN).

Catalog Number: 102989-588

Supplier: Adipogen

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