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Supplier: Diagnostic Biosystems
Description: This antibody recognizes a protein of 38kDa, identified as synaptophysin. It labels normal neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary gland, thyroid, lung, pancreas, gastrointestinal mucosa, Paneth’s cells in the gastrointestinal tract and gastric parietal cells. Neurons in the brain, spinal cord, and retina are also labeled. In combination with anti-chromogranin A and anti-NSE, anti-synaptophysin is very useful in the identification of normal neuroendocrine cells and neuroendocrine neoplasms.

Catalog Number: (76634-562)
Supplier: Diagnostic Biosystems
Description: This antibody recognizes thyroglobulin in hyperplastic and neoplastic thyroid. Thyroglobulin is a protein of 670 kDa consisting of two identical subunits. Thyroglobulin is synthesized by the follicular epithelial cells of the thyroid.


Catalog Number: (76634-334)
Supplier: Diagnostic Biosystems
Description: Epithelial antigen is a cell surface glycoprotein and is broadly distributed in epithelial cells and displays a highly conserved expression in carcinomas. Epithelial antigen has been shown to play an important role as a tumor cell marker in lymph nodes from patients with esophageal carcinoma. Epithelial antigen can be used to distinguish between basal cell and basosquamous carcinomas and squamous cell carcinoma of the skin.


Supplier: Diagnostic Biosystems
Description: This antibody is specific to a protein of 110 kDa, identified as androgen receptor

Catalog Number: (95027-222)
Supplier: Diagnostic Biosystems
Description: The Copper Stain Kit (For Microwave) is intended for the demonstration of copper deposits in tissue sections.


Supplier: Diagnostic Biosystems
Description: UnoVue Mouse/Rabbit AP Detection Reagent is a non-biotin one-step detection reagent suitable for demonstrating antigens in formalin-fixed paraffin-embedded tissues and cryostat sections.

Supplier: Diagnostic Biosystems
Description: UnoVue Mouse HRP Detection Reagent is a non-biotin one-step detection reagent suitable for demonstrating antigens in formalin-fixed paraffin-embedded tissues and frozen sections.

Supplier: Diagnostic Biosystems
Description: This antibody recognizes purified insulin from the pancreas of human, as well as proinsulin from human.

Catalog Number: (76634-454)
Supplier: Diagnostic Biosystems
Description: Inhibin is a dimeric glycoprotein hormone from the TGF-β family made of α and β subunits. This antibody recognizes the 32kDa α subunit of human inhibin. Inhibin α is expressed in a wide variety of human tissues, such as brain, prostate, adrenal, granulose cells of ovary, sertoli cells of testis and in fetoplacental unit.


Catalog Number: (76634-840)
Supplier: Diagnostic Biosystems
Description: The progesterone receptor (PgR) is an estrogen-regulated protein. It has been proposed that expression of PgR indicates a responsive estrogen receptor (ER) pathway. A number of studies have shown that PgR determination provides supplementary information to ER, both in predicting response to endocrine therapy and estimating survival. PgR has proved superior to ER as a prognostic indicator in some studies.


Catalog Number: (76634-888)
Supplier: Diagnostic Biosystems
Description: PRAME (Preferentially expressed Antigen in Melanoma) is a tumorassociated antigen and is a member of the family of cancer testis antigens (CTA). PRAME is expressed in malignant cells, including leukaemias, Hodgkin's lymphoma, breast cancer, and primary and metastatic melanomas. PRAME has low or no expression in normal tissues except for in testis, ovary, placenta, adrenals and endometrium.


Supplier: Diagnostic Biosystems
Description: Monoclonal Anti-BCL-10 reacts specifically with human bcl-10. The epitope recognized by the antibody resides within amino acids 122-168 of human bcl-10 molecule. BCL-10, also designated as CIPER, mE10, cE10, CARMEN, and CLAP, is an N-terminal CARD (caspase recruitment domain) containing protein. It is a cellular homologue of the equine herpesvirus-2 protein E-10 (VCLAP). BCL-10 was implicated in the regulation of apoptosis by interacting with caspase 9, enhancing procaspase 9 processing, and triggering its activation when overexpressed in the cell. Bcl-10 cellular overexpression induces JNK, P38, and NF-kB activation. Deregulation of BCL-10 expression was also demonstrated to be involved in cellular oncogenesis.

Catalog Number: (76634-296)
Supplier: Diagnostic Biosystems
Description: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pH <5.7) and basic (pH >6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad-spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g., squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.


Supplier: Diagnostic Biosystems
Description: This antibody reacts with the 57 kDa intermediate filament protein present in the cells of mesenchymal origin. The antibody does not show any cross-reactivity with other intermediate filament proteins.

Catalog Number: (76634-226)
Supplier: Diagnostic Biosystems
Description: Villin is One of the gelsolin family of calcium regulated actin binding proteins. Normally expressed in the brush border of epithelial cells lining the gastrointestinal tract, hepatobiliary tract and renal proximal convoluted tubules. In colorectal carcinoma, villin is highly expressed. In practice, villin can be included in the panel used for metastatic carcinoma to detect colorectal origin.


Catalog Number: (76634-620)
Supplier: Diagnostic Biosystems
Description: This antibody reacts with chains of human IgA. This antibody has been adsorbed to a very high level of specificity.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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