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Anti-IgG Donkey Polyclonal Antibody (Texas Red®)

Description: Anti-Chicken Igg (Handl) (Donkey) Antibody Texas Red* Conjugated (Min X Bv Gt Gp Ham Hs Hu Ms Rb Rt And Sh Serum Proteins) - 603-709-C37 Chicken Igg (Handl) Antibody Texas Red* Conjugated Pre-Adsorbed 1 Mg

Catalog Number: RL603-709-C37

Supplier: Rockland Immunochemical

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Goose Serum Sterile, Rockland Immunochemicals

Description: Sterile Serum

Catalog Number: 75928-170

Supplier: Rockland Immunochemical

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Anti-RGPD5 Rabbit Polyclonal Antibody

Description: The RANBP2-like and GRIP domain containing 5 protein (RGPD5) has high similarity to RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. The gene coding for RGPD5 is thought to have arisen from a gene duplication event of RANBP2 as these highly homologous genes are located close to each other at chromosome 2q11-q12. RGPD5 was identified as an HIV dependency factor (HDF), suggesting that RGPD5 may be an important drug target in HIV treatment. At least two isoforms of RGPD5 are known to exist, of which the shorter isoform is expressed primarily in testis, while the longer of the two is expressed at low levels in a number of somatic tissues.

Catalog Number: 75931-558

Supplier: Rockland Immunochemical

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Guinea Pig Gamma Globulin Fraction

Description: Lyophilized Gamma Globulin Fraction

Catalog Number: 75928-296

Supplier: Rockland Immunochemical

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Anti-SNAI2 Rabbit Polyclonal Antibody

Description: Slug antibody dectects human Slug protein. Slug, a member of the Snail family of C2H2-type zinc finger transcription factors, was initially identified to be involved in epithelial-mesenchymal transitions as well as the formation of the neural tube during vertebrate embryogenesis. Like Snail, Slug transcription can be induced by growth factors such as FGF, BMP, and TGF-beta. Once expressed, Slug will bind E-box regions of promoters and repress transcription of genes such as E-cadherin and Claudin-. More recently, its expression in breast, esophogeal, and colorectal carcinomas has been correlated with poor prognosis for survival. Furthermore, Slug can protect hemapoietic progenitor cells from radiation-induced apoptosis by repressing the p53-mediated transcription of Puma, a BH3-only antagonist of the anti-apoptotic members of the Bcl-2 family. Slug antibody has no cross-reactivity to Snail protein. Anti-Slug antibodies are ideal for investigators involved in transcription factors, cell cycle proteins and cancer research.

Catalog Number: 75932-022

Supplier: Rockland Immunochemical

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Anti-PLEKHM2 Rabbit Polyclonal Antibody

Description: PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.

Catalog Number: 75935-008

Supplier: Rockland Immunochemical

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Anti-PAK1 Rabbit Polyclonal Antibody

Description: PAKs, p21 activated kinases, are a family of serine/threonine protein kinases comprised of six isoforms, PAK1-6, and they play important roles in cytoskeleton dynamics, cell survival and proliferation. Each of these isoforms contains a C-terminal catalytic domain and an N-terminal regulatory domain with a small G protein binding motif. OSR1, oxidative stress response 1, is activated only by osmotic stresses, like sorbital or NaCl. It has been predicted that OSR1 phosphorylates PAK1 in the regulatory domain at thr84 and inhibits activation of JNK and MAPK pathway. It has also been suggested that OSR1 may have a regulating function with actin cytoskeleton because it can phosphorylate PAK1 at thr84 and bind to gelsolin. PAK1 pT84 Antibody is ideal for researchers interested in cell cycle research.

Catalog Number: 75934-074

Supplier: Rockland Immunochemical

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