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Supplier: Bachem Americas
Description: Screening analogs of the cyclic lactam melanocortin agonist MTII led to the identification of the agoutimimetic SHU9119. The cyclopeptide SHU9119 shares pharmacological properties with the agouti peptide in that it is a potent antagonist of the melanocortin-4 receptor and a less potent antagonist of the melanocortin-3 receptor.

Supplier: Bachem Americas
Description: Sequence: H-Cys(Trt)-OH
Synonym(s): STLC

Supplier: Bachem Americas
Description: Highly efficient coupling additive, a safer, non-explosive alternative to HOBt.

Supplier: Bachem Americas
Description: Sequence: Z-Tyr-Val-Ala-Asp-AFC
Synonym(s): Z-YVAD-AFC

Supplier: Bachem Americas
Description: Galanin-like peptide (GALP), first isolated from the porcine hypothalamus and subsequently also identified in rats and humans, is a 60 amino acid neuropeptide that unlike galanin, has a non-amidated C-terminus. Its amino acid residues (9-21) are identical to the biologically active N-terminal (1-13) fragment of galanin. In contrast to galanin which is relatively non-selective, receptor binding studies revealed that GALP had a high affinity for the galanin receptor 2 (GALR2) and a lower affinity for the GALR1 receptor. Furthermore, it could be demonstrated that GALP stimulates food intake with a ten fold higher orexigenic activity than galanin and may also affect emotional state in the CNS.

Supplier: Bachem Americas
Description: Sequence: Fmoc-Asp-OtBu

Supplier: Bachem Americas
Description: Sequence: H-Hyp-OH

Supplier: Bachem Americas
Description: Sequence: H-Ser(PO₃H₂)-OH

Supplier: Bachem Americas
Description: Sequence: H-Tyr(PO₃H₂)-OH

Supplier: Bachem Americas
Description: Please see also α-MSH (corresponds to acetyl-ACTH (1-13) amide, H-1075), α-MSH (free acid) (acetyl-ACTH (1-13), H-1070), and (Des-acetyl)-α-MSH (H-4390). Wied: Pituitary Adrenal System Hormones and Behaviour. Symposium on Developments in Endocrinology (1976) / Anon.: ACTH and Related Peptides: Structure, Regulation, and Action. Ann. N.Y. Acad. Sci. 297, 1 (1977) / A.V.Schally: Aspects of Hypothalamic Regulation of the Pituitary Gland. Science 202, 18 (1978) / R.Schwyzer: Studies on Polypeptide Receptors. A Critical View on the Mechanism of ACTH Action. Bull. Schweiz. Acad. Med. Wiss. 34, 263 (1978).

Supplier: Bachem Americas
Description: Sequence: Z-D-Ser(tBu)-OH

Supplier: Bachem Americas
Description: Sequence: Fmoc-N-Me-Tyr(tBu)-OH

Supplier: Bachem Americas
Description: Triglycine to hexaglycine.

Supplier: Bachem Americas
Description: For Elcatonin see H-2214.

Supplier: Bachem Americas
Description: For the long-acting GLP-1 analog liraglutide see H-6724.

Catalog Number: (H-1388.0001BA)
Supplier: Bachem Americas
Description: The amyloid precursor protein (APP) is cleaved within the amyloid β-protein region by a putative APP secretase to release its extracellular portion. Gelatinase A, the matrix metalloproteinase MMP-2, possesses such APP secretase-like activity, effectively hydrolyzing also the synthetic amyloid β-protein fragment (10-20) YEVHHQKLVFF at the normal processing site, the Lys¹⁶-Leu¹⁷ bond (Km approx. 0.13 mM).


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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