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Catalog Number: (103260-084)
Supplier: Southern Biotechnology
Description: FITC Anti-Monkey IgG for use in flow cytometry and western blotting assays.


Catalog Number: (100242-034)
Supplier: Southern Biotechnology
Description: Goat F(ab’)2 IgG-APC for use as a control in flow cytometry assays.


Catalog Number: (100245-514)
Supplier: Southern Biotechnology
Description: PE Anti-Chicken IgM antibody for use in flow cytometry assays.


Catalog Number: (100243-992)
Supplier: Southern Biotechnology
Description: The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid production of primitive hematopoietic progenitor cells. A variety of cytokines act synergistically with SCF to stimulate proliferation and differentiation of bone marrow progenitor cells. For example, SCF plus IL-7 can stimulate the combined myeloid and B cell differentiation of uncommitted hematopoietic progenitor cells. SCF/c-Kit also participates in erythropoiesis in both the bone marrow and spleen. Loss-of-function mutations for SCF/c-Kit lead to a variety of pleiotropic developmental defects while gain-of-function mutations can lead to constitutive activation of the kit receptor and links to cancer. Examples of the former are mast cell deficiency and severe macrocytic anemia while the latter mutation has been identified in mastocytomas.


Catalog Number: (100244-754)
Supplier: Southern Biotechnology
Description: Goat Anti-Rabbit IgG-TRITC antibody for use in immunohistochemistry / immunocytochemistry assays.


Catalog Number: (100245-704)
Supplier: Southern Biotechnology
Description: APC Anti-Human IgG Fc antibody for use in flow cytometry assays.


Catalog Number: (101442-514)
Supplier: Southern Biotechnology
Description: Mouse IgG2b-APC/CY5.5 for use as a control in flow cytometry assays.


Catalog Number: (101442-944)
Supplier: Southern Biotechnology
Description: CD8 is a 33 kDa transmembrane glycoprotein expressed as either a CD8αα homodimer or CD8αβ heterodimer. It is expressed on the “cytotoxic/suppressor” subpopulation of peripheral T cells. CD8 functions primarily as a coreceptor with MHC class I-restricted TCR’s in antigen recognition.


Catalog Number: (103265-008)
Supplier: Southern Biotechnology
Description: Purified Rabbit Anti-Goat IgG(H+L) antibody with minimal reactivity to human serum proteins for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100244-550)
Supplier: Southern Biotechnology
Description: Goat Anti-Rat IgG-Biotin antibody with minimal reactivity to mouse proteins for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and separation assays.


Catalog Number: (100245-894)
Supplier: Southern Biotechnology
Description: CD19 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is expressed at all stages of B cell differentiation except terminally differentiated plasma cells. It is also present on the cell surface of follicular dendritic cells. CD19 associates with CD21, CD81, Leu 13 and/or MHC Class II molecules to form a signal transduction complex on the B cell surface. This signaling complex modulates the activation threshold for the B cell antigen receptor (BCR).


Catalog Number: (101442-846)
Supplier: Southern Biotechnology
Description: HRP Anti-Rabbit Ig antibody for use in ELISA assays.


Catalog Number: (103265-534)
Supplier: Southern Biotechnology
Description: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the TNF family of cytokines. This type II transmembrane protein is expressed by several cytotoxic immune cells, including natural killer cells and activated T cells, and is selective for tumorigenic and virally infected cells. TRAIL can bind to DR4 and DR5 receptors on target cells which facilitates recruitment of numerous signaling proteins to form a death-inducing signaling complex. This signaling complex is then believed to propagate the apoptotic signal through the recruitment and activation of caspase-8. Numerous studies have identified TRAIL as a potent apoptotic factor in a variety of human cancer cell lines, but this cytokine does not appear to affect normal cell lines. Therefore, the selectivity and anti-tumorigenic properties of TRAIL make it an intriguing and potentially therapeutic agent in the treatment of cancer.


Catalog Number: (100242-642)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG1-HRP antibody with minimal reactivity to human proteins for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.


Catalog Number: (101442-888)
Supplier: Southern Biotechnology
Description: c-Kit is a 145 kDa transmembrane receptor-type protein tyrosine kinase encoded by the c-Kit proto-oncogene and is the receptor for stem cell factor (SCF). c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis, and adhesion. The amino acid sequence of chicken c-kit shows 63% identity to mouse c-Kit and exhibits similar expression patterns in RNA blot analysis suggesting similar biological roles.


Catalog Number: (103265-298)
Supplier: Southern Biotechnology
Description: CD11b is the 165 kDa αM chain which combines with the CD18 β2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2).


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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