You Searched For: AMERICAN RADIOLABELED CHEM MS


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Description: CD44, also known as phagocytic glycoprotein-1 (Pgp-1), exists as a large number of different isoforms resulting from alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type I transmembrane protein. Other variable isoforms containing glycosaminoglycans have molecular weights ranging from 110 to 250 kDa and are widely expressed on hematopoietic and non-hematopoietic cells. CD44 contributes to the adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. It also plays a functional role in cell migration, lymphocyte homing, and adhesion during hematopoiesis and lymphocyte activation.
Catalog Number: 101442-918
Supplier: Southern Biotechnology


Description: Goat F(ab')2 Anti-Rat IgG-PE/CY5 (SPRD) antibody with minimal reactivity to mouse proteins for use in flow cytometry assays.
Catalog Number: 100244-568
Supplier: Southern Biotechnology


Description: CD4 is a type I transmembrane glycoprotein expressed on approximately 70% of thymocytes, 10% of spleen cells, and 45% of peripheral blood lymphocytes but less than 1% of bursal cells. The monoclonal antibody CT-4 inhibits both PHA- and Con A-induced proliferative responses of splenocytes and PWM-induced IL-2 production. This antibody also reacts with turkey and quail as demonstrated by flow cytometry.
Catalog Number: 103260-136
Supplier: Southern Biotechnology


Description: Donkey Anti-Rabbit IgG(H+L)-FITC antibody with minimal reactivity to human, mouse, and rat serum proteins for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
Catalog Number: 100245-288
Supplier: Southern Biotechnology


Description: Goat F(ab')2 Anti-Mouse Ig-Alexa Fluor 488 antibody with minimal reactivity to human proteins for use in flow cytometry, immunocytochemistry, and western blotting assays.
Catalog Number: 103264-206
Supplier: Southern Biotechnology


Description: Goat Anti-Chicken IgY(H+L)-FITC antibody with minimal reactivity to human, mouse, rat, bovine, horse, hamster, goat, sheep, rabbit, and guinea pig serum proteins for use in fluorescent assays.
Catalog Number: 103264-962
Supplier: Southern Biotechnology


Description: CD4 is a type I transmembrane glycoprotein expressed on most thymocytes and the helper/inducer subpopulation of mature T lymphocytes of all mouse strains tested. CD4 has also been detected at low density on pluripotent hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic lymphoid precursors. The CD4 antigen functions as a co-receptor, interacting with class II major histocompatability complex (MHC) molecules in the recognition of foreign antigens by T cells. In vivo and in vitro treatment with the GK1.5 monoclonal antibody effectively depletes CD4+ cells. GK1.5 also blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.
Catalog Number: 100243-126
Supplier: Southern Biotechnology


Description: Rabbit Anti-Sheep IgG(H+L)-Biotin antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.
Catalog Number: 100245-128
Supplier: Southern Biotechnology


Description: Goat Anti-Human Ig-Alexa Fluor 555 antibody for use in immunocytochemistry and western blotting assays.
Catalog Number: 103264-704
Supplier: Southern Biotechnology


Description: CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The monoclonal antibody C363.29B recognizes an epitope on the 25 kDa ε chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble C363.29B can activate primed and naïve T cell in vitro. Immobilized C363.2B9 monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. The monoclonal antibody is cytolytic, easily used for cell surface staining, and a good immunoprecipitating antibody.
Catalog Number: 100243-098
Supplier: Southern Biotechnology


Description: Rat IgG2b-HRP for use as a control in immunohistochemistry assays.
Catalog Number: 103259-706
Supplier: Southern Biotechnology


Description: Goat Anti-Mouse IgG1-Alexa Fluor 488 antibody for use in immunocytochemistry and fluorescent assays.
Catalog Number: 103265-602
Supplier: Southern Biotechnology


Description: FITC Anti-Human IgA2 antibody for use in flow cytometry, immunohistochemistry, and western blotting assays.
Catalog Number: 100245-768
Supplier: Southern Biotechnology


Description: CD158e1 is a 70 kDa transmembrane glycoprotein and a killer cell immunoglobulin (Ig)-like receptor (KIR) that is expressed on a subset of natural killer cells and T cells. The monoclonal antibody DX9 is expressed on a subset of CD3-, CD56+ NK cells isolated from peripheral blood at varying levels (<0.1% to 61%) among individuals but not on thymocytes, B lymphocytes, granulocytes, or monocytes. Interactions with CD158e1 and certain MHC HLA-B antigens on a target cell inhibits cytotoxicity, possibly preventing target cell lysis and death. KIR and MHC class I interactions may regulate NK and T cell response to antigen stimulation.
Catalog Number: 103265-444
Supplier: Southern Biotechnology


Description: Purified Anti-Type II Collagen antibody for use in ELISA, immunohistochemistry / immunocytochemistry, electron microscopy, western blotting, and immunoprecipitation assays.
Catalog Number: 100242-966
Supplier: Southern Biotechnology


Description: CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80 (B7-1) and CD86 (B7-2) on B cells and other antigen presenting cells and plays an important role in the interaction between T cells and B cells. CD28 is a costimulatory receptor involved in many, but not all, T-cell independent immune responses.
Catalog Number: 100243-388
Supplier: Southern Biotechnology


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