You Searched For: 4-(tert-Butoxycarbonylamino)benzylamine

Description: Feline CD5, a member of the scavenger receptor family of cell surface receptors, is a type I transmembrane glycoprotein that is expressed on most thymocytes and mature T lymphocytes. CD5 is thought to function in both cell-cell recognition and signal transduction. The monoclonal antibody f43 is useful as a pan T cell marker.

Catalog Number: 100245-390

Supplier: Southern Biotechnology

Sale

Description: Goat Anti-Rhesus IgG(H+L)-PE antibody for use in multiplex and other fluorescent assays.

Catalog Number: 103260-094

Supplier: Southern Biotechnology

Sale

Description: In the mouse, CD8 exists in two forms – (i) a CD8 heterodimer composed of an α chain (CD8α) and a β chain (CD8β); and (ii) a homodimer of two α chains. The heterodimer is found on the surface of essentially all thymocytes and the “suppressor/cytotoxic” subpopulation of mature T lymphocytes. Subsets of intestinal intraepithelial lymphocytes express CD8α without CD8β. It has been suggested that CD8+β- T cells mature extrathymically, while development of the CD8α+β+ population of T cells is thymus-dependent. CD8 acts as a coreceptor with MHC Class I-restricted T cell receptors in antigen recognition and positive selection of MHC class I-restricted CD8+ T cells. In vivo and in vitro treatment with the 53-6.7 monoclonal antibody effectively depletes CD8α+ cells. The 53-6.7 monoclonal antibody also blocks allogeneic help specific for class I MHC antigens and T cell responses to IL-2.

Catalog Number: 100243-172

Supplier: Southern Biotechnology

Sale

Description: Mouse IgG1-Alexa Fluor 700 for use as a control in flow cytometry assays.

Catalog Number: 103259-614

Supplier: Southern Biotechnology

Sale

Description: Goat F(ab')2 Anti-Human IgG-Biotin antibody for use in ELISA, flow cytometry, immunohistochemistry, western blotting, ELISpot, and separation assays.

Catalog Number: 100244-296

Supplier: Southern Biotechnology

Sale

Description: CD11b is the 165 kDa αM chain which combines with the CD18 β2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2).

Catalog Number: 103265-302

Supplier: Southern Biotechnology

Sale

Description: The monoclonal antibody 15-5-5 reacts with the H-2Dk class I alloantigen. It cross-reacts with H-2Kd and with cells from mice with the H-2f haplotype. The antibody does not react with other (e.g., a, b, p, q, r, s) haplotypes.

Catalog Number: 100244-128

Supplier: Southern Biotechnology

Sale

Description: Purified Rabbit F(ab')2 Anti-Human IgG(H+L) antibody with minimal reactivity to mouse proteins for use in ELISA assays.

Catalog Number: 100244-918

Supplier: Southern Biotechnology

SDS Sale

Description: Rabbit Anti-Goat IgG(H+L)-HRP antibody with minimal reactivity to human serum proteins for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.

Catalog Number: 103265-014

Supplier: Southern Biotechnology

Sale

Description: Mouse IgG2b-PE for use as a control in flow cytometry assays.

Catalog Number: 100241-938

Supplier: Southern Biotechnology

Sale

Description: CD62L, also known as L-selectin, is a type I transmembrane glycoprotein with lectin-like and epidermal growth factor-like domains. It binds to sialylated oligosaccharide determinants on high endothelial venules (HEV) in peripheral lymph nodes. In the mouse, CD62L is expressed on most thymocytes and on peripheral leukocytes, including B and T lymphocytes, neutrophils, monocytes, and eosinophils. This member of the selectin family of cell adhesion molecules appears to be required for lymphocyte homing to peripheral lymph nodes and for leukocyte extravasation at sites of inflammation. Expression of CD62L on lymphocytes and neutrophils is rapidly down-regulated upon cell activation and the level of CD62L expression, along with other markers, distinguishes naive T cells from effector/memory T cells. The monoclonal antibody MEL-14 blocks in vitro binding of lymphocytes to peripheral lymph node HEV and inhibits in vivo lymphocyte extravasation into peripheral lymph nodes and the late stages of leukocyte rolling.

Catalog Number: 103259-934

Supplier: Southern Biotechnology

Sale

Description: Neutralite Avidin, Host: deglycosylated avidin purified from egg white, Buffer Formulation Supplied in PBS/NaN3, Concentration 0.5 mg/mL, Store at 2-8 deg C, Conjugate: CY3, Applications: ELISA, FLISA, Flow Cytometry, Size: 0.1 mg

Catalog Number: 103265-132

Supplier: Southern Biotechnology

Sale

Description: The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid production of primitive hematopoietic progenitor cells. A variety of cytokines act synergistically with SCF to stimulate proliferation and differentiation of bone marrow progenitor cells. For example, SCF plus IL-7 can stimulate the combined myeloid and B cell differentiation of uncommitted hematopoietic progenitor cells. SCF/c-Kit also participates in erythropoiesis in both the bone marrow and spleen. Loss-of-function mutations for SCF/c-Kit lead to a variety of pleiotropic developmental defects while gain-of-function mutations can lead to constitutive activation of the kit receptor and links to cancer. Examples of the former are mast cell deficiency and severe macrocytic anemia while the latter mutation has been identified in mastocytomas.

Catalog Number: 103259-978

Supplier: Southern Biotechnology

Sale

Description: The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid production of primitive hematopoietic progenitor cells. A variety of cytokines act synergistically with SCF to stimulate proliferation and differentiation of bone marrow progenitor cells. For example, SCF plus IL-7 can stimulate the combined myeloid and B cell differentiation of uncommitted hematopoietic progenitor cells. SCF/c-Kit also participates in erythropoiesis in both the bone marrow and spleen. Loss-of-function mutations for SCF/c-Kit lead to a variety of pleiotropic developmental defects while gain-of-function mutations can lead to constitutive activation of the kit receptor and links to cancer. Examples of the former are mast cell deficiency and severe macrocytic anemia while the latter mutation has been identified in mastocytomas.

Catalog Number: 103264-640

Supplier: Southern Biotechnology

Sale

Description: Goat Anti-Mouse IgG(H+L)-Biotin antibody for use in ELISA assays.

Catalog Number: 103264-410

Supplier: Southern Biotechnology

Sale

Description: Mouse IgG2a-PE for use as a control in flow cytometry assays.

Catalog Number: 100241-918

Supplier: Southern Biotechnology

Sale