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Catalog Number: (103264-872)
Supplier: Southern Biotechnology
Description: Goat Anti-Rabbit IgG Fab-Biotin antibody for use in ELISA assays.


Catalog Number: (103264-512)
Supplier: Southern Biotechnology
Description: Alexa Fluor 488 Anti-Type II Collagen antibody for use in immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100243-804)
Supplier: Southern Biotechnology
Description: The CD45 antigen is an essential regulator of leukocyte activation and development and is now known to be a protein tyrosine phosphatase, e.g., CD45 is able to dephosphorylate the Src family of protein kinases. This activity is now known to be required for signal transduction induced by T and B cell antigen receptor engagement, cytokine signaling, and Fc receptor stimulation. The functional state of CD45 also has a pronounced effect on lymphocyte development. CD45 exists in multiple forms, such as the restricted variants (CD45R; see companion products 1660, 1665, 1675, 1685, and 1820) and as allelic forms CD45.1 (Ly-5.1) and CD45.2 (Ly-5.2). The former arises as a result of alternative splicing of different exons. The specificity of antibodies to CD45.1 and CD45.2 has been exploited in studies where resolution of donor and recipient cells is essential, such as in gene therapy or bone marrow transplantation. The monoclonal antibody A20 recognizes all mouse leukocytes expressing the CD45.1 allotype.


Catalog Number: (100246-042)
Supplier: Southern Biotechnology
Description: CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3 is expressed on 70-80% of normal peripheral blood lymphocytes and on 10-20% of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation. The monoclonal antibody UCHT1 reacts with the 20 kDa ε chain of the CD3/TCR complex.


Catalog Number: (100246-028)
Supplier: Southern Biotechnology
Description: CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3 is expressed on 70-80% of normal peripheral blood lymphocytes and on 10-20% of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation. The monoclonal antibody UCHT1 reacts with the 20 kDa ε chain of the CD3/TCR complex.


Catalog Number: (103265-024)
Supplier: Southern Biotechnology
Description: Donkey Anti-Mouse IgG(H+L)-Alexa Fluor 555 antibody with minimal reactivity to human serum proteins for use in immunohistochemistry / immunocytochemistry assays.


Catalog Number: (100242-846)
Supplier: Southern Biotechnology
Description: Biotin Anti-Mouse IgA antibody for use in ELISA, flow cytometry, immunohistochemistry, and western blotting assays.


Catalog Number: (100242-704)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Mouse IgG2b antibody with minimal reactivity to human proteins for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.


Catalog Number: (100244-548)
Supplier: Southern Biotechnology
Description: Goat Anti-Rat IgG-Texas Red antibody with minimal reactivity to mouse proteins for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.


Catalog Number: (100246-096)
Supplier: Southern Biotechnology
Description: CD8 is a 33 kDa transmembrane glycoprotein expressed as either a CD8αα homodimer or CD8αβ heterodimer. It is expressed on the “cytotoxic/suppressor” subpopulation of peripheral T cells. CD8 functions primarily as a coreceptor with MHC class I-restricted TCR’s in antigen recognition.


Supplier: Southern Biotechnology
Description: CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107a is expressed by activated T cells, macrophages, dendritic cells, activated platelets, tonsillar epithelium, and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential where they may increase adhesion to extracellular matrix and endothelium.

Catalog Number: (103260-118)
Supplier: Southern Biotechnology
Description: Anti-Biotin may be used for indirect immunostaining when working with a biotinylated primary antibody. As an effective alternative to avidin, Anti-Biotin amplifies signal and reduces background that can be caused by avidin and its derivatives.


Catalog Number: (103265-538)
Supplier: Southern Biotechnology
Description: Glial fibrillary acid protein (GFAP) is a member of the type III intermediate filament family of proteins. GFAP is heavily expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and functions of the cell’s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cell; however, its precise function remains poorly understood. In adults, GFAP levels increase in response to the proliferation of astrocytes associated with Alzheimer’s disease, epilepsy, and multiple sclerosis. Antibodies specific for GFAP are useful as markers of astrocytic cells and neural stem cells as well as for distinguishing neoplasms of astrocytic origin from other neoplasms in the central nervous system.


Catalog Number: (100246-116)
Supplier: Southern Biotechnology
Description: CD8 is a 33 kDa transmembrane glycoprotein expressed as either a CD8αα homodimer or CD8αβ heterodimer. It is expressed on the “cytotoxic/suppressor” subpopulation of peripheral T cells. CD8 functions primarily as a coreceptor with MHC class I-restricted TCR’s in antigen recognition.


Catalog Number: (103265-082)
Supplier: Southern Biotechnology
Description: Donkey Anti-Goat IgG(H+L)-Biotin antibody with minimal reactivity to human, mouse, rat, hamster, rabbit, chicken, horse, and guinea pig serum proteins for use in ELISA, western blotting, and immunohistochemistry assays.


Catalog Number: (103265-484)
Supplier: Southern Biotechnology
Description: FITC Anti-Mouse IL-2 antibody for use in flow cytometry and immunohistochemistry assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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