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Description: Goat Anti-Mouse IgG2c-Biotin antibody for use in ELISA assays.
Catalog Number: 103264-450
Supplier: Southern Biotechnology


Description: CD69, also known as very early activation (VEA) antigen, is a disulfide-linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa. It is a C-type lectin most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. CD69 is widely expressed on hematopoietic cells, including lymphocytes, neutrophils and eosinophils. Although not detectable on resting lymphocytes, its expression is rapidly upregulated upon activation of T, B and NK cells, and neutrophils. Constitutive expression of CD69 on subsets of thymocytes suggests that it may be involved in regulation of developmental events in addition to its role in activation of a variety of hematopoietic cells. The monoclonal antibody H1.2F3 augments PMA-induced T-cell proliferation and induces redirected lysis of Fc receptor-bearing target cells by NK cells.
Catalog Number: 100243-620
Supplier: Southern Biotechnology


Description: Goat Anti-Human IgG Fc-HRP antibody with minimal reactivity to mouse, bovine, and horse serum proteins for use in ELISA assays.
Catalog Number: 103260-046
Supplier: Southern Biotechnology


Description: The “classical” MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic α chains noncovalently associated with the invariant β2-microglobulin. These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+ T cells during T cell ontogeny. The monoclonal antibody 34-1-2S binds to a common determinant in the α3 domains of H-2Kd and H-2Dd in the presence or absence of β2 microglobulin. It cross reacts with the α3 domain of H-2Kb.
Catalog Number: 100244-102
Supplier: Southern Biotechnology


Description: Purified Anti-Human GM-CSF antibody for use in ELISA, ELISpot, immunoprecipitation, and multiplex assays.
Catalog Number: 100242-288
Supplier: Southern Biotechnology


Description: Goat Anti-Mouse IgG-AP antibody with minimal reactivity to human proteins for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.
Catalog Number: 100242-482
Supplier: Southern Biotechnology


Description: In the mouse, CD8 exists in two forms – (i) a CD8 heterodimer composed of an α chain (CD8α) and a β chain (CD8β); and (ii) a homodimer of two α chains. The heterodimer is found on the surface of essentially all thymocytes and the “suppressor/cytotoxic” subpopulation of mature T lymphocytes. Subsets of intestinal intraepithelial lymphocytes express CD8α without CD8β. It has been suggested that CD8+β- T cells mature extrathymically, while development of the CD8α+β+ population of T cells is thymus-dependent. CD8 acts as a coreceptor with MHC Class I-restricted T cell receptors in antigen recognition and positive selection of MHC class I-restricted CD8+ T cells. In vivo and in vitro treatment with the 53-6.7 monoclonal antibody effectively depletes CD8α+ cells. The 53-6.7 monoclonal antibody also blocks allogeneic help specific for class I MHC antigens and T cell responses to IL-2.
Catalog Number: 100243-190
Supplier: Southern Biotechnology


Description: CD69, also known as very early activation (VEA) antigen, is a disulfide-linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa. It is a C-type lectin most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. CD69 is widely expressed on hematopoietic cells, including lymphocytes, neutrophils and eosinophils. Although not detectable on resting lymphocytes, its expression is rapidly upregulated upon activation of T, B and NK cells, and neutrophils. Constitutive expression of CD69 on subsets of thymocytes suggests that it may be involved in regulation of developmental events in addition to its role in activation of a variety of hematopoietic cells. The monoclonal antibody H1.2F3 augments PMA-induced T-cell proliferation and induces redirected lysis of Fc receptor-bearing target cells by NK cells.
Catalog Number: 100243-616
Supplier: Southern Biotechnology


Description: Goat Anti-Mouse Lambda-FITC antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
Catalog Number: 100242-600
Supplier: Southern Biotechnology


Description: Goat Anti-Mouse IgG3-APC/CY7 antibody with minimal reactivity to human proteins for use in flow cytometry assays.
Catalog Number: 101442-674
Supplier: Southern Biotechnology


Description: Goat Anti-Rabbit IgG-TRITC antibody for use in immunohistochemistry / immunocytochemistry assays.
Catalog Number: 100244-754
Supplier: Southern Biotechnology


Description: Purified Rabbit Anti-Goat IgG(H+L) antibody with minimal reactivity to human serum proteins for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
Catalog Number: 103265-008
Supplier: Southern Biotechnology


Description: CD8 is a 33 kDa transmembrane glycoprotein expressed as either a CD8αα homodimer or CD8αβ heterodimer. It is expressed on the “cytotoxic/suppressor” subpopulation of peripheral T cells. CD8 functions primarily as a coreceptor with MHC class I-restricted TCR’s in antigen recognition.
Catalog Number: 101442-944
Supplier: Southern Biotechnology


Description: CD103 is a member of the integrin series of adhesion molecules. This antigen defines a developmentally important subset of T cells, namely mucosal T cells including all IEL (intraepithelial lymphocytes) and ~20% of lamina propria T cells. Expression of CD103 is more restricted outside these mucosal organs appearing at lower levels on T cell subsets of the lymph node, dendritic epidermis, and periphery. In non-epithelial CD103+ T cells there is a bias toward expression on CD8+ cells. The 2E7 monoclonal antibody exhibits antigen immunoprecipitation patterns similar if not identical to the rat anti-mouse CD103 monoclonal antibody M290. 2E7 is reported to have signal-inducing activity in a redirected lysis assay and to costimulate IEL and CD8+ lymph node cells in conjunction with anti-TCR in vitro which runs counter to the usual inhibition of CTL by anti-integrins. This costimulatory activity is also shared by the monoclonal antibody M290. The property of costimulation is not unique to the mouse since the combination of anti-human αIEL plus anti-TCR will produce similar proliferation in human cells with the exception that CD8+ cells are not stimulated.
Catalog Number: 103259-970
Supplier: Southern Biotechnology


Description: Donkey Anti-Rabbit IgG(H+L)-PE antibody with minimal reactivity to human, mouse, and rat serum proteins for use in flow cytometry assays.
Catalog Number: 100245-296
Supplier: Southern Biotechnology


Description: 1.0mg.
Catalog Number: 100245-346
Supplier: Southern Biotechnology


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