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Catalog Number: (100242-024)
Supplier: Southern Biotechnology
Description: Goat IgG-APC for use as a control in flow cytometry assays.


Catalog Number: (103264-684)
Supplier: Southern Biotechnology
Description: HRP Anti-Hamster IgG2/IgG3 antibody for use in ELISA assays.


Catalog Number: (100245-290)
Supplier: Southern Biotechnology
Description: Donkey Anti-Rabbit IgG(H+L)-AP antibody with minimal reactivity to human, mouse, and rat serum proteins for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (101442-898)
Supplier: Southern Biotechnology
Description: CY5 Anti-Human IgG Fc antibody for use in flow cytometry and western blotting assays.


Catalog Number: (100242-276)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse Ig-Texas Red antibody with minimal reactivity to human proteins for use in immunohistochemistry / immunocytochemistry and flow cytometry assays.


Catalog Number: (103264-748)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Human IgM-Alexa Fluor 647 antibody for use in flow cytometry and immunocytochemistry assays.


Catalog Number: (100242-882)
Supplier: Southern Biotechnology
Description: Purified Anti-Mouse Kappa antibody for use in ELISA, flow cytometry, immunocytochemistry, and western blotting assays.


Catalog Number: (100246-100)
Supplier: Southern Biotechnology
Description: CD8 is a 33 kDa transmembrane glycoprotein expressed as either a CD8αα homodimer or CD8αβ heterodimer. It is expressed on the “cytotoxic/suppressor” subpopulation of peripheral T cells. CD8 functions primarily as a coreceptor with MHC class I-restricted TCR’s in antigen recognition.


Catalog Number: (101442-866)
Supplier: Southern Biotechnology
Description: Goat Anti-Chicken IgY(H+L)-Biotin antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100246-524)
Supplier: Southern Biotechnology
Description: CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107a is expressed by activated T cells, macrophages, dendritic cells, activated platelets, tonsillar epithelium, and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential where they may increase adhesion to extracellular matrix and endothelium.


Catalog Number: (103264-620)
Supplier: Southern Biotechnology
Description: The TCRγδ heterodimer of the CD3/T cell receptor complex is clonotypic and consists of Ig-like variable and constant domains. It is expressed during thymopoiesis and on the small subpopulation of γδ TCR-expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are γδ+ and have limited receptor diversity. The TCRγδ heterodimer recognizes peptide antigen bound to MHC antigens and subsequent signal transduction mediated by the invariant chains leads to T cell activation. The monoclonal antibody UC7-13D5 is specific for the γδ heterodimer and plate-bound UC7-13D5 activates γδ TCR-bearing cells. This antibody does not react with αβ TCR-expressing T cells.


Catalog Number: (100244-110)
Supplier: Southern Biotechnology
Description: The monoclonal antibody 34-5-8S reacts with a conformational epitope on H-2Dd MHC Class I found on the N-terminal domains of α1 and α2 chains when complexed with β2-microglobulin. The antibody does not react with H-2Dd α chains synthesized in vitro. Weak cross-reactivity with cells from mice of the H-2b, H-2q, and H-2s haplotypes has been observed by flow cytometric analysis. Reactivity with cells from mice of the H-2f, H-2k, H-2p, and H-2r haplotypes has not been observed. 34-5-8S has been reported to block the recognition of H-2Dd by Ly-49A+, Ly-49C+, and Ly-49G2+ natural killer cells.


Catalog Number: (100243-088)
Supplier: Southern Biotechnology
Description: CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3ε is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. 500-A2 recognizes an epitope on the 25 kDa ε chain of the CD3/TCR complex of mouse strains tested.


Catalog Number: (100243-956)
Supplier: Southern Biotechnology
Description: Murine CD79 is a disulfide-linked heterodimer composed of an α chain (CD79a) and a β chain (CD79b) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation.


Catalog Number: (103265-258)
Supplier: Southern Biotechnology
Description: CD54, also known as intercellular cell adhesion molecule-1 (ICAM-1), is a 90 kDa type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It exhibits a wide tissue distribution being expressed on both hematopoietic and non-hematopoietic cells. ICAM-1 expression on leukocytes is low but is rapidly upregulated upon activation. Expression on endothelium and other non-hematopoietic cells is strongly upregulated by inflammatory mediators. The ligands of CD54 are CD11a/LFA-1α and CD11b/Mac-1α. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels particularly in areas of inflammation. CD54 on antigen-presenting cells (APC) contributes to antigen-specific T cell activation presumably by enhancing interactions between T cells and APC.


Catalog Number: (100242-738)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG3-TRITC antibody with minimal reactivity to human proteins for use in immunohistochemistry / immunocytochemistry assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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