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Catalog Number: (103264-806)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgG(H+L)-Biotin antibody with minimal reactivity to rabbit, mouse, rat, bovine, horse, hamster, goat, sheep, chicken, and guinea pig serum proteins for use in ELISA assays.


Catalog Number: (103264-742)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgM-Alexa Fluor 555 antibody for use in immunohistochemistry / immunocytochemistry and western blotting assays.


Catalog Number: (100243-330)
Supplier: Southern Biotechnology
Description: CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P-selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes.


Catalog Number: (100243-368)
Supplier: Southern Biotechnology
Description: The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity α chain of the IL-2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O-linked carbohydrates and has a short cytoplasmic tail. CD25 is expressed on activated T cells, B cells, NK cells, and monocytes of all mouse strains tested. Expression of CD25 on activated T lymphocytes is transitory and endogenously regulated. CD25 is expressed on precursor B cells in bone marrow. Its expression is initiated by functional rearrangement and expression of IgM heavy chain genes and is down-regulated when immature B cells mature and express IgD. It is expressed at a higher level on CD4+CD8+ thymocytes. It is also expressed on cultured epidermal Langerhans cells. The biochemical features of murine CD25 have been characterized in detail. The 3C7 monoclonal antibody reacts with an epitope of CD25 which is distinct from that recognized by clone 7D4. 3C7, used in combination with 7D4 in culture, results in higher levels of inhibition of proliferation driven by IL-2 and generation of alloreactive CTL than either of these monoclonal antibodies alone.


Catalog Number: (100242-348)
Supplier: Southern Biotechnology
Description: Purified Anti-Human IL-13 antibody for use in ELISA assays.


Catalog Number: (100241-886)
Supplier: Southern Biotechnology
Description: Mouse IgM-PE/CY5 (SPRD) for use as a control in flow cytometry assays.


Catalog Number: (100245-120)
Supplier: Southern Biotechnology
Description: Rabbit Anti-Sheep IgG(H+L)-FITC antibody for use in immunohistochemistry / immunocytochemistry and western blotting assays.


Catalog Number: (100243-732)
Supplier: Southern Biotechnology
Description: BP-1, also known as Ly-51 and 6C3 antigen, is a type II homodimeric transmembrane glycoprotein formed by two disulfide-linked chains of 140 kDa. Originally identified on the surface of pre-B cell lymphomas the cDNA encoding BP-1 has been cloned and found to represent aminopeptidase A. It is expressed at high levels on bone marrow stromal cell lines which support in vitro B lymphopoiesis and on a wide variety of mouse tissues known to possess aminopeptidase activity. Subsets of normal bone marrow pre-B and B cells express low levels of BP-1 which is rapidly upregulated on pre-B cells in the presence of IL-7. The BP-1 marker is commonly used to identify B cells in different stages of development.


Catalog Number: (101442-546)
Supplier: Southern Biotechnology
Description: Rat IgG2a-APC/CY5.5 for use as a control in flow cytometry assays.


Catalog Number: (100246-538)
Supplier: Southern Biotechnology
Description: Glycophorin A (CD235a) is a 36 kDa sialoglycoprotein that is the most predominant sialoglycoprotein of the erythroid lineage. Glycophorin A is the major contributor to the net negative surface charge of the mature red blood cell (RBC) membrane thereby minimizing cell to cell interactions in circulation. The monoclonal antibody CMRF14 binds to glutaraldehyde fixed or neuraminidase treated erythrocytes but not to papain, trypsin, or pronase treated erythrocytes.


Catalog Number: (100246-334)
Supplier: Southern Biotechnology
Description: CD57 represents a 110 kDa oligosaccharide antigenic determinant present on a variety of polypeptides, lipids, and chondroitan sulfate proteoglycans. It is expressed on 7-35% of normal peripheral blood lymphocytes, including subsets of NK cells and CD8+ T lymphocytes. The carbohydrate is expressed on various cell adhesion molecules in the nervous system and is suggested to play a role in cell–cell and cell–substrate interactions.


Catalog Number: (101442-776)
Supplier: Southern Biotechnology
Description: CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B-cell specific stimuli with peak expression at 18-42 hours after stimulation. CD86, along with CD80 (B7-1), is an important accessory molecule in T cell costimulation via its interaction with CD28 and CD152 (CTLA-4). Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. The monoclonal antibody GL1 blocks mixed lymphocyte reactions and stimulation of T cells by antigen-presenting cells.


Catalog Number: (103264-596)
Supplier: Southern Biotechnology
Description: CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes, and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN γ, IL-1, TNF-α, lipopolysaccharide, and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1.


Catalog Number: (100245-812)
Supplier: Southern Biotechnology
Description: AP Anti-Human IgG4 Fc antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100244-600)
Supplier: Southern Biotechnology
Description: Biotin Anti-Rat IgG2a antibody for use in flow cytometry, ELISA, immunohistochemistry, and ELISpot assays.


Catalog Number: (100246-310)
Supplier: Southern Biotechnology
Description: CD51 represents the integrin αV chain that associates with integrin β3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils, and platelets. CD51 is the most promiscuous integrin α subunit as it can form heterodimers with the β1 (CD29), β3 (CD61), β5, β6 and β8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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