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Catalog Number: (103264-792)
Supplier: Southern Biotechnology
Description: Goat Anti-Human Ig Fab-FITC antibody for use in fluorescent assays.


Catalog Number: (103264-396)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG Fc-Biotin antibody for use in ELISA and western blotting assays.


Catalog Number: (103264-388)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Mouse IgG(H+L)-Alexa Fluor 555 antibody with minimal reactivity to human proteins for use in immunohistochemistry / immunocytochemistry and western blotting assays.


Supplier: Southern Biotechnology
Description: CD5, also known as Lyt-1, is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B-cell antigen CD72. The frequency of CD5+ B cells exhibits strain-dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells. Binding of CD5 on the T cell surface can augment alloantigen- or mitogen-induced lymphocyte proliferation and induces increased cytosolic free calcium, IL-2 secretion, and IL-2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T-cell and B-cell receptors.

Catalog Number: (103264-594)
Supplier: Southern Biotechnology
Description: The monoclonal antibody 5H10.27 reacts with the α5 chain (VLA-5) of the CD49e/CD29 heterodimeric fibronectin receptor. It is expressed on thymocytes, activated T cells, mast cells, and a variety of mouse cell lines. Soluble 5H10.27 antibody inhibits VLA-5-mediated functions in vitro. Immobilized 5H10.27 has also been demonstrated to costimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3 monoclonal antibody.


Catalog Number: (100244-646)
Supplier: Southern Biotechnology
Description: PE Anti-Rat Kappa antibody for use in flow cytometry assays.


Catalog Number: (100244-576)
Supplier: Southern Biotechnology
Description: FITC Anti-Rat IgG1 antibody for use in flow cytometry and immunohistochemistry assays.


Catalog Number: (100246-526)
Supplier: Southern Biotechnology
Description: CD107b, also known as lysosomal-associated membrane protein 2 (LAMP-2), is a heavily glycosylated type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains and is a ligand for E-selectin-mediated cell adhesion. CD107b is expressed in lysosomal/endosomal membranes and on the surface of activated platelets and some tumor cell lines including U937 and KG1a. LAMP-2 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential where they may increase adhesion to extracellular matrix and endothelium.


Catalog Number: (100241-974)
Supplier: Southern Biotechnology
Description: Mouse IgA-PE for use as a control in flow cytometry assays.


Catalog Number: (100244-830)
Supplier: Southern Biotechnology
Description: Porcine CD3ε is a member of the T-cell receptor-associated CD3 complex. It is found on a subpopulation of thymocytes and on all pig T lymphocytes. The monoclonal antibody PPT3 is mitogenic when presented to peripheral blood mononuclear cells in immobilized form.


Catalog Number: (103264-720)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgG Fc-Alexa Fluor 555 antibody with minimal reactivity to rabbit, mouse, rat, bovine, horse, hamster, goat, sheep, chicken, and guinea pig serum proteins for use in fluorescent assays.


Catalog Number: (100242-174)
Supplier: Southern Biotechnology
Description: Purified Human IgG1 Lambda for use as a standard in ELISA.


Catalog Number: (103265-506)
Supplier: Southern Biotechnology
Description: Alexa Fluor 647 Anti-Mouse IFN-gamma antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (103264-904)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Rabbit IgG(H+L) antibody for use in ELISA assays.


Catalog Number: (100243-812)
Supplier: Southern Biotechnology
Description: The CD45 antigen is an essential regulator of leukocyte activation and development and is now known to be a protein tyrosine phosphatase, e.g., CD45 is able to dephosporylate the Src family of protein kinases. This activity is known to be required for signal transduction induced by T and B cell antigen receptor engagement, cytokine signaling, and Fc receptor stimulation. The functional state of CD45 also has a pronounced effect on lymphocyte development. CD45 exists in multiple forms, such as the restricted variants (CD45R; see companion products 1660, 1665, 1675, 1685 and 1820) and as allelic forms CD45.1 (Ly-5.1) and CD45.2 (Ly-5.2). The specificity of antibodies to CD45.1 and CD45.2 has been exploited in studies where resolution of donor and recipient cells is essential, such as in gene therapy or bone marrow transplantation. The monoclonal antibody 104 recognizes CD45 (leukocyte common antigen) on all leukocytes of mouse strains expressing the CD45.2 allotype (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129).


Catalog Number: (100242-986)
Supplier: Southern Biotechnology
Description: Protein tyrosine residues are phosphorylated as a result of intracellular protein kinase activation (e.g., via growth factors) during normal growth and development and in oncogenesis. The most abundant population of target proteins for tyrosine phosphorylation is cell surface glycoproteins. Antibodies to phosphotyrosine enable the detection, isolation, and characterization of proteins containing phosphotyrosine. The monoclonal antibody PY20 prevents internalization of activated receptors (e.g., EGFR) when microinjected into cells. The affinity of PY20 for phosphotyrosine is approximately 10-6 to 10-7 M. PY20 binding to phosphorylated tyrosines can be inhibited by free phosphotyrosine and phenylphosphate but not by phosphoserine, phosphothreonine, or free phosphate.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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