You Searched For: OPTEM


3,022  results were found

SearchResultCount:"3022"

Sort Results

List View Easy View (new)

Rate These Search Results

Catalog Number: (100243-588)
Supplier: Southern Biotechnology
Description: CD62L, also known as L-selectin, is a type I transmembrane glycoprotein with lectin-like and epidermal growth factor-like domains. It binds to sialylated oligosaccharide determinants on high endothelial venules (HEV) in peripheral lymph nodes. In the mouse, CD62L is expressed on most thymocytes and on peripheral leukocytes, including B and T lymphocytes, neutrophils, monocytes, and eosinophils. This member of the selectin family of cell adhesion molecules appears to be required for lymphocyte homing to peripheral lymph nodes and for leukocyte extravasation at sites of inflammation. Expression of CD62L on lymphocytes and neutrophils is rapidly down-regulated upon cell activation and the level of CD62L expression, along with other markers, distinguishes naive T cells from effector/memory T cells. The monoclonal antibody MEL-14 blocks in vitro binding of lymphocytes to peripheral lymph node HEV and inhibits in vivo lymphocyte extravasation into peripheral lymph nodes and the late stages of leukocyte rolling.


Catalog Number: (100245-116)
Supplier: Southern Biotechnology
Description: Rabbit Anti-Human IgG(H+L)-Biotin antibody with minimal reactivity to mouse proteins for use in ELISA and immunohistochemistry assays.


Catalog Number: (100246-180)
Supplier: Southern Biotechnology
Description: CD15 is a carbohydrate antigen found on the cell surface of neutrophils and monocytes, but not on basophils, platelets, lymphocytes, or erythrocytes. CD15 may function in adhesion as its ligand is L-selectin (CD62L).


Catalog Number: (100242-612)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse Lambda-PE antibody for use in flow cytometry assays.


Catalog Number: (100246-168)
Supplier: Southern Biotechnology
Description: CD14 is a 55 kDa glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells, and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.


Catalog Number: (103264-494)
Supplier: Southern Biotechnology
Description: HRP Anti-Mouse IgG1 antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100243-746)
Supplier: Southern Biotechnology
Description: The TCRγδ heterodimer of the CD3/T cell receptor complex is clonotypic and consists of Ig-like variable and constant domains. It is expressed during thymopoiesis and on the small subpopulation of γδ TCR-expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are γδ+ and have limited receptor diversity. The TCRγδ heterodimer recognizes peptide antigen bound to MHC antigens and subsequent signal transduction mediated by the invariant chains leads to T cell activation. The monoclonal antibody UC7-13D5 is specific for the γδ heterodimer and plate-bound UC7-13D5 activates γδ TCR-bearing cells. This antibody does not react with αβ TCR-expressing T cells.


Catalog Number: (103264-820)
Supplier: Southern Biotechnology
Description: Goat Anti-Rat IgG-Alexa Fluor 647 antibody with minimal reactivity to mouse proteins for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100244-884)
Supplier: Southern Biotechnology
Description: The monoclonal antibody BB6-10A10 stains the following percentages of surface immunoglobulin (sIg) positive cells in porcine lymphoid tissues - 11-15% in peripheral blood, 22-23% in mesenteric lymph nodes, 79-87% in ileal Peyer’s patches (ILPP), 6-17 in spleen, and 0% in thymus. While identification of the antigen(s) that are found predominantly on ILPP B cells and which are recognized by BB6-10A10 is speculative, the antibody appears to react with an immature population of B cells in the follicles of ILPPs and with a subpopulation of sIglow B cells in lymph nodes.


Catalog Number: (103259-624)
Supplier: Southern Biotechnology
Description: Mouse IgG2a-Pacific Blue for use as a control in flow cytometry assays.


Catalog Number: (100246-284)
Supplier: Southern Biotechnology
Description: CD45RA is a 220 kDa exon A-dependent isoform of CD45. It is expressed on 40-50% of CD4+ peripheral T cells, 50% of peripheral CD8+ T cells, and a portion of B lymphocytes and monocytes.


Catalog Number: (100243-794)
Supplier: Southern Biotechnology
Description: The CD45 antigen is an essential regulator of leukocyte activation and development and is now known to be a protein tyrosine phosphatase, e.g., CD45 is able to dephosphorylate the Src family of protein kinases. This activity is now known to be required for signal transduction induced by T and B cell antigen receptor engagement, cytokine signaling, and Fc receptor stimulation. The functional state of CD45 also has a pronounced effect on lymphocyte development. CD45 exists in multiple forms, such as the restricted variants (CD45R; see companion products 1660, 1665, 1675, 1685, and 1820) and as allelic forms CD45.1 (Ly-5.1) and CD45.2 (Ly-5.2). The former arises as a result of alternative splicing of different exons. The specificity of antibodies to CD45.1 and CD45.2 has been exploited in studies where resolution of donor and recipient cells is essential, such as in gene therapy or bone marrow transplantation. The monoclonal antibody A20 recognizes all mouse leukocytes expressing the CD45.1 allotype.


Catalog Number: (100243-204)
Supplier: Southern Biotechnology
Description: CD11b (integrin αM subunit) combines with CD18 (integrin β2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.


Catalog Number: (100245-800)
Supplier: Southern Biotechnology
Description: FITC Anti-Human IgG4 pFc' antibody for use in flow cytometry, immunohistochemistry, and western blotting assays.


Catalog Number: (100245-726)
Supplier: Southern Biotechnology
Description: HRP Anti-Human IgG2 Fc antibody for use in ELISA, immunocytochemistry, western blotting, and ELISpot assays.


Catalog Number: (100243-076)
Supplier: Southern Biotechnology
Description: CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3ε is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. 500-A2 recognizes an epitope on the 25 kDa ε chain of the CD3/TCR complex of mouse strains tested.


Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • State issued document with your organization's Federal Tax ID Number
  • State issued document with your organization's Resale Tax ID Number
  • City or County issued Business License
  • State Department of Health Services License
  • Any other ID issued by the State that includes the business name and address

* Please note if your account is within the State of California two of these pieces of identification will be required.
VWR will not lift restrictions for residential shipping addresses.

-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
1,825 - 1,840 of 3,022
no targeter for Bottom