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Supplier: Biotium
Description: This antibody reacts with human CD59, a 20 kDa glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. CD59 regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. It inhibits formation of MAC, thus protecting cells from complement-mediated lysis. Genetic defects in GPI-anchor attachment, that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobinuria (PNH). This MAb is useful for study on GPI-anchored proteins, PNH and CD59 functions. CD59 is widely distributed on cells in all tissues. The expression of CD59 on erythrocytes is important for their survival.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Catalog Number: (89139-598)
Supplier: Biotium
Description: The fluorescence of NBD is highly dependent on the environment; it is virtually nonfluorescent in water but becomes strongly green fluorescent in hydrophobic media. NBD-ethylenediamine can be readily coupled to activated carboxy groups or sulfonyl chlorides.


Supplier: Biotium
Description: PGP9.5 (UCHL-1), Monoclonal antibody, Clone: 31A3, Host: Mouse, Species reactivity: Zebrafish, Pig, Dog, Cow, Sheep, Rat, Human, Guinea Pig, Rabbit, Isotype: IgG2a, kappa, Conjugate: biotin, Immunogen: Native UchL1 (PGP9.5) protein from brain, Application: IF, Size: 100uL

Supplier: Biotium
Description: CD37 Monoclonal antibody, Clone: IPO-24, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: CF568, Immunogen: Spleen cells of a patient with hairy cell leukemia, Synonyms: GP52 40, Tspan-26, TSPAN26, Application: IF, FC, Size: 100uL

Supplier: Biotium
Description: This antibody recognizes a protein of ~76 kDa, which is identified as Nucleolin (NCL). It is the major nucleolar phosphoprotein of growing eukaryotic cells. NCL is located mainly in dense fibrillar regions of the nucleolus. It is found associated with intranucleolar chromatin and pre-ribosomal particles. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly.This MAb can be used to stain the nucleoli in cell or tissue preparations and can be used as a marker of the nucleoli in subcellular fractions. It produces a speckled pattern in the nuclei of cells of normal and malignant cells and may be used to stain the nucleoli of cells in fixed or frozen tissue sections. It can be used with paraformaldehyde fixed frozen tissue or cell preparations and formalin fixed, paraffin-embedded tissue sections.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Supplier: Biotium
Description: IgM Immunoglobulin, Monoclonal antibody, Clone: IM260 + ICO-30, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Heavy chain of human IgM, Synonyms: AGM1; IGHM, Application: IF, IHC (formalin), Flow cytometry, Size: 100uL

Supplier: Biotium
Description: HER-2 / CD340, Monoclonal antibody, Clone: HRB2/258, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Recombinant intracellular domain of human HER-2 protein, Synonyms: p185, CD340, Verb b2, Size: 500uL

Supplier: Biotium
Description: Neurofilament (H+L), Monoclonal antibody, Clone: NF421 + NFL736, Host: Mouse, Species reactivity: Mouse, Pig, Rat, Human, Chicken, Isotype: IgG's, Conjugate: CF594, Immunogen: Recombinant human neurofilament heavy sub-unit (RT-97) & light sub-unit (NR-4), Size: 100uL

Supplier: Biotium
Description: CD32 Monoclonal antibody, Clone: 8.7, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: K562 and FcgRII L cellsUnigene 352642, Application: Immunofluorescence, Flow cytometry, Size: 100uL

Supplier: Biotium
Description: CD44 Standard Monoclonal antibody, Clone: HCAM/1097, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG2b, kappa, Conjugate: CF647, Immunogen: Recombinant human HCAM protein, Application: IF, Immunohistology (formalin), FC, Size: 500 uL

Supplier: Biotium
Description: CD74 Monoclonal antibody, Clone: LN-2 + CLIP/813, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF488A, Immunogen: SU-DHL-4 lymphoma cells ; Recombinant full-length human CD74 protein, Application: IF, IHC, FC, Size: 100uL

Supplier: Biotium
Description: TNF alphA, Monoclonal antibody, Clone: TNF655, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Recombinant human TNF-alpha, Application: Immunofluorescence, Flow cytometry, Size: 500uL

Supplier: Biotium
Description: NucView® 488 Caspase-3 substrate kits for real-time apoptosis monitoring in live cells are bundled with the NucView® caspase-3 substrate and various apoptosis or necrosis markers for convenient multi-color experiments.

Supplier: Biotium
Description: Hepatocyte Specific Antigen, Monoclonal antibody, Clone: HSA133, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: CF640R, Immunogen: SK-H1A9-2 human hepatocellular carcinoma cells, Application: Immunofluorescence, Size: 500uL

Catalog Number: (75885-584)
Supplier: Biotium
Description: CD10 Monoclonal antibody, Clone: CB-CALLA, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: BSA-free, Immunogen: Human CD10Unigene 307734, Application: Immunofluorescence, Flow cytometry, Size: 50 uL


Supplier: Biotium
Description: This antibody recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb 1A7G6B6 for PSA tests.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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