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Description: p40 (p63 delta) is a marker recently determined to be highly specific for squamous basal cells in the immunohistochemistry (IHC) application. The current more routinely recommended marker, p63, appears to have less specificity compared to p40, especially on squamous cell tumors. The ability to differentiate between lung adenocarcinoma vs. squamous cell carcinoma is difficult and has bearing on the different therapeutic avenues for each subtype treatment. p63 antibody's ability to distinguish between the tumor types appears to be inferior when compared to p40. The ability to utilize an antibody probe for p40 as a squamous cell marker bolsters its use for future sub-classification of lung cancers, especially by immunohistochemical techniques.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Catalog Number: 75980-544

Supplier: Biotium

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Description: CD50 Monoclonal antibody, Clone: 186-2G9, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, kappa, Conjugate: CF568, Immunogen: Stimulated human leukocytes, Synonyms: ICAMR, Intercellular adhesion molecule 3 (ICAM3), Application: IF, Immunohistology, Size: 100uL

Catalog Number: 75911-994

Supplier: Biotium

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Description: insensitive to pH, and has a narrower emission peak resULting in less fluorescence spillover in the red channel.

Catalog Number: 97065-524

Supplier: Biotium

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Description: Mitochondrial Marker, Monoclonal antibody, Clone: MTC754, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF640R, Immunogen: Semi-purified mitochondrial preparation, Application: Immunofluorescence, Immunohistology (formalin), Size: 500uL

Catalog Number: 75961-942

Supplier: Biotium

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Description: Near-infrared dyes offer highly sensitive and specific detection in complex biological systems, because cells and tissues have intrinsically low autofluorescence in the near-IR region

Catalog Number: 89411-570

Supplier: Biotium

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Description: CD71 Monoclonal antibody, Clone: DF1513, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: KG1 acute myeloid leukemia cell line, Synonyms: Mtvr-1, p90, TFR1, Application: IF, WB, FC, Size: 500 uL

Catalog Number: 75918-054

Supplier: Biotium

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Description: CD56 / NCAM Monoclonal antibody, Clone: 123C3.D5, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Membrane preparation of a small cell lung carcinoma, Synonyms: NCAM, Leu-19, NKH1, Size: 100uL

Catalog Number: 75914-588

Supplier: Biotium

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Description: MAGE A1, Monoclonal antibody, Clone: MA454, Host: Mouse, Species reactivity: Human, Dog, Rat, Isotype: IgG1, kappa, BSA-free, Immunogen: Human MAGE-A1 full length recombinant protein, Synonyms: cancer/testis antigen 1.1, CT1.1, MAGE1A, Application: IF, Size: 50 uL

Catalog Number: 75957-024

Supplier: Biotium

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Description: This product is prepared by labeling IgG with CF350. CF350 is a blue fluorescent dye spectrally similar to AMCA. However, compared to AMCA, CF350 is more water-soluble, more photostable and at least 50% more fluorescent on proteins.

Catalog Number: 89138-694

Supplier: Biotium

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Description: This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with this MAb is completely blocked by the peptide used for raising this antibody. TGF alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Catalog Number: 75976-108

Supplier: Biotium

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Description: This antibody recognizes a protein of 25-26 kDa, identified as the bcl-2 α oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2 α oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2 α protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Catalog Number: 75884-804

Supplier: Biotium

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Description: Cytokeratin, HMW Monoclonal antibody, Clone: KRTH/1076, Host: Mouse, Species reactivity: Human, Rat, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Recom human KRT76 protein, Synonyms: KRT2B, KRT2P, HUMCYT2A, Application: IF, WB, FC, Size: 500 uL

Catalog Number: 75916-868

Supplier: Biotium

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Description: Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Catalog Number: 75971-010

Supplier: Biotium

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Description: EGP40 is a 40-43 kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Catalog Number: 75893-250

Supplier: Biotium

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Description: Anti-IgG Goat Antibody (CF™ 633)

Catalog Number: 89493-226

Supplier: Biotium

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Description: ACTH Monoclonal antibody, Clone: AH26, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG1, kappa, Conjugate: BSA-free, Immunogen: Synthetic peptide corresponding to aa1-24 of human ACTH, Synonyms: Adrenocorticotropin, Application: IF, IHC, Size: 50 uL

Catalog Number: 75883-702

Supplier: Biotium

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