You Searched For: BIOTIUM, INC

Supplier: Biotium

Description: Transgelin / SM22-alphA, Monoclonal antibody, Clone: TAGLN/247, Host: Mouse, Species reactivity: Pig, Cow, Human, Rabbit, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Recombinant full-length human transgelin (TAGLN) protein, Application: IF, Size: 500uL

Supplier: Biotium

Description: This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Supplier: Biotium

Description: SUMO-2, Monoclonal antibody, Clone: SUMO2/1199, Host: Mouse, Species reactivity: Human, Rat, Isotype: IgG1, Conjugate: purified, Immunogen: Recombinant human SUMO2 protein, Application: Immunofluorescence, Immunohistology (formalin), Flow cytometry, Size: 500uL

Supplier: Biotium

Description: This antibody recognizes a 70 kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP This antibody recognizes germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Supplier: Biotium

Description: FOXP3 Monoclonal antibody, Clone: 3G3, Host: Mouse, Species reactivity: Mouse, Monkey, Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Full-length His-tagged mouse FOXP3 protein, Application: Immunofluorescence, Flow cytometry, Size: 100uL

Catalog Number: (75895-990)

Supplier: Biotium

Description: CD43 Monoclonal antibody, Clone: DF-T1, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: BSA-free, Immunogen: Myeloblastic KG1 cells, Synonyms: GALGP, GPL115, Application: IF, IHC, FC, Size: 50 uL

Sale

Supplier: Biotium

Description: Lambda Light Chain, Monoclonal antibody, Clone: ICO-106, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, kappa, Conjugate: CF488A, Immunogen: Purified IgG myeloma proteins coupled to polyaminostyren, Synonyms: BJP, Application: IF, Size: 500uL

Catalog Number: (89493-308)

Supplier: Biotium

Description: Anti-IgG Rabbit Antibody (CF™ 633)

Sale

Supplier: Biotium

Description: SUMO-2, Monoclonal antibody, Clone: SUMO2/1199, Host: Mouse, Species reactivity: Human, Rat, Isotype: IgG1, Conjugate: CF405S, Immunogen: Recombinant human SUMO2 protein, Application: Immunofluorescence, Immunohistology (formalin), Flow cytometry, Size: 500uL

Supplier: Biotium

Description: CD11A Monoclonal antibody, Clone: Cris-3, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: CF488A, Immunogen: Stimulated human leukocytes, Synonyms: Antigen CD11A (p180), Application: IF, FC, Size: 100uL

Supplier: Biotium

Description: CELA3B Monoclonal antibody, Clone: CELA3B/1218, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Recom human CELA3B protein, Synonyms: ELA3B, Elastase IIIB, Protease E, Application: IF, FC, Size: 100uL

Supplier: Biotium

Description: Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Supplier: Biotium

Description: This antibody recognizes a protein of ~76 kDa, which is identified as Nucleolin (NCL). It is the major nucleolar phosphoprotein of growing eukaryotic cells. NCL is located mainly in dense fibrillar regions of the nucleolus. It is found associated with intranucleolar chromatin and pre-ribosomal particles. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly.This MAb can be used to stain the nucleoli in cell or tissue preparations and can be used as a marker of the nucleoli in subcellular fractions. It produces a speckled pattern in the nuclei of cells of normal and malignant cells and may be used to stain the nucleoli of cells in fixed or frozen tissue sections. It can be used with paraformaldehyde fixed frozen tissue or cell preparations and formalin fixed, paraffin-embedded tissue sections.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Supplier: Biotium

Description: CD13 Monoclonal antibody, Clone: WM15, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Human AML cells, Synonyms: Aminopeptidase M, Application: ImmunoFluorescence, IHC, Flow Cytometry, Size: 100uL

Supplier: Biotium

Description: CD79 is a disulfide-linked heterodimer of mb-1 (or CD79a) and B29 (or CD79b) polypeptidesIt is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Supplier: Biotium

Description: Phosphotyrosine, Monoclonal antibody, Clone: PY20, Host: Mouse, Species reactivity: All species, Isotype: IgG2b, Conjugate: purified, Immunogen: Phosphotyrosine conjugated to KLH, Synonyms: P-Tyr, Application: Immunofluorescence, Size: 100uL