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Description: Involucrin, Monoclonal antibody, Clone: IVRN/827, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, BSA-free, Immunogen: Purified involucrin from human keratinocytes, Synonyms: IVL, Application: Immunofluorescence, Flow cytometry, Size: 50 uL

Catalog Number: 75955-124

Supplier: Biotium

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Description: Anti-IgG2a Goat Polyclonal Antibody (CF™ 555)

Catalog Number: 71004-224

Supplier: Biotium

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Description: Cdc20 Monoclonal antibody, Clone: AR12, Host: Mouse, Species reactivity: Human, Isotype: IgG1, Conjugate: CF488A, Immunogen: Urea-denatured His6 Cdc20 human recombinant protein, Synonyms: CDC20, CDC20A, p55CDC, P55CDC-LSB, Application: IF, IHC, FC, Size: 100uL

Catalog Number: 75909-176

Supplier: Biotium

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Description: CD79 is a disulfide-linked heterodimer of mb-1 (or CD79a) and B29 (or CD79b) polypeptidesIt is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Catalog Number: 75910-666

Supplier: Biotium

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Description: IL-6 (Rat), Monoclonal antibody, Clone: MP5-20F3, Host: Rat, Species reactivity: Mouse, Isotype: IgG2a, kappa, BSA-free, Immunogen: Recombinant mouse IL-6 protein, Application: Immunofluorescence, Neutralization, Flow cytometry, Size: 50 uL

Catalog Number: 75981-292

Supplier: Biotium

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Description: IgA Immunoglobulin, Monoclonal antibody, Clone: IA761, Host: Mouse, Species reactivity: Human, Isotype: IgG1, Conjugate: CF647, Immunogen: Purified human alpha heavy chain, Synonyms: A2m Marker; Ig alpha 1 Chain C Region, Application: IF, IHC (formalin), Size: 500uL

Catalog Number: 75953-932

Supplier: Biotium

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Description: This MAb recognizes a 60 kDa antigen associated with the mitochondria in human cells. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. It recognizes an antigen associated with the mitochondria in human cells only. It can be used to stain the mitochondria in cell or tissue preparations and can be used as a mitochondrial marker in subcellular fractions. It produces a spaghetti-like pattern in normal and malignant cells and may be used to stain mitochondria of cells in fixed or frozen tissue sections. It can also be used with paraformaldehyde fixed frozen tissue or cell preparations. This MAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells, including neurons and embryonic stem cells.

Catalog Number: 75961-716

Supplier: Biotium

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Description: TNF alphA, Monoclonal antibody, Clone: TNFA/1172, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, BSA-free, Immunogen: Recombinant human TNF-alpha, Application: Immunofluorescence, Flow cytometry, Size: 50 uL

Catalog Number: 75977-284

Supplier: Biotium

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Description: Involucrin, Monoclonal antibody, Clone: IVRN/827, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Purified involucrin from human keratinocytes, Synonyms: IVL, Application: Immunofluorescence, Flow cytometry, Size: 100uL

Catalog Number: 75954-450

Supplier: Biotium

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Description: This antibody recognizes the epsilon-chain of CD3 (Workshop V; Code: CD03.09), which consists of five different polypeptide chains (designated as γ, δ, ε, ζ, and η) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

Catalog Number: 75895-424

Supplier: Biotium

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Description: PS2, Monoclonal antibody, Clone: TFF1/1091, Host: Mouse, Species reactivity: Human, Monkey, Isotype: IgG3, kappa, Conjugate: CF647, Immunogen: synthetic peptide from C-terminus of human TFF1 protein, Synonyms: Breast Cancer Estrogen Inducible Protein, Application: IF, Size: 100uL

Catalog Number: 75972-206

Supplier: Biotium

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Description: TAG-72 / CA72.4, Monoclonal antibody, Clone: CC49, Host: Mouse, Species reactivity: Human, Hamster, Dog, Cow, Rat, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Membrane-enriched fraction of breast carcinoma, Synonyms: CA72.4, Size: 500uL

Catalog Number: 75974-864

Supplier: Biotium

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Description: Estrogen Receptor beta 1 Monoclonal antibody, Clone: ESR2/686, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: purified, Immunogen: C-terminus fragment, Synonyms: Erb, ESR BETA, ESR2, Application: IF, IHC, WB, FC, Size: 500 uL

Catalog Number: 75926-082

Supplier: Biotium

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Description: This antibody recognizes keratin 5 (58 kDa) and keratin 8 (52.5 kDa). Simple epithelia express cytokeratin 8 in combination with 18. On the other hand, basal cells of stratified epithelia express cytokeratin 5 paired with 14. This antibody therefore, reacts with a wide range of epithelia and their carcinomas.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Catalog Number: 75921-746

Supplier: Biotium

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Description: HSP60, Monoclonal antibody, Clone: LK1, Host: Mouse, Species reactivity: Mouse, Hamster, Monkey, Pig, Dog, Cow, Sheep, Rat, Human, Chicken, Rabbit, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Recombinant human HSPD1 protein, Application: IF, IHC Western, Size: 100uL

Catalog Number: 75953-612

Supplier: Biotium

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Description: This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Catalog Number: 75981-034

Supplier: Biotium

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