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Description: P27 / KIP1, Monoclonal antibody, Clone: SX53G8), Host: Mouse, Species reactivity: Mouse, Monkey, Rat, Human, Isotype: IgG's, BSA-free, Immunogen: Mouse recombinant p27 protein (DCS-72.F6), Synonyms: CDKN1B, CDKN4, Cyclin Dependent Kinase Inhibitor 1B, Size: 50 uL

Catalog Number: 75967-244

Supplier: Biotium

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Description: This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Catalog Number: 75918-648

Supplier: Biotium

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Description: IgG Immunoglobulin, Monoclonal antibody, Clone: ICO-97, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF647, Immunogen: Purified polyclonal human Ig Gamma Chain, Application: Immunofluorescence, Immunohistology (formalin), Flow, Size: 500uL

Catalog Number: 75954-220

Supplier: Biotium

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Description: CD34 Monoclonal antibody, Clone: HPCA1/763, Host: Mouse, Species reactivity: Human, Isotype: IgG1 and IgG2b, kappa, Conjugate: CF488A, Immunogen: Recom full-length human HPCA1 protein, Synonyms: HPCA1, Mucosialin, Application: IF, IHC, FC, Size: 100uL

Catalog Number: 75894-348

Supplier: Biotium

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Description: This antibody recognizes a protein of 55 kDa, identified as CD14 (also known lipopolysaccharide receptor). CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Catalog Number: 75886-894

Supplier: Biotium

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Description: Anti-IgG Goat Polyclonal Antibody (Biotin)

Catalog Number: 97065-576

Supplier: Biotium

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Description: IgA Immunoglobulin, Monoclonal antibody, Clone: IA-HISA43, Host: Mouse, Species reactivity: Human, Isotype: IgG1, Conjugate: CF594, Immunogen: Purified human alpha heavy chain, Synonyms: A2m Marker; Ig alpha 1 Chain C Region, Application: IF, IHC, Size: 500uL

Catalog Number: 75952-192

Supplier: Biotium

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Description: PLAP (Placental Alkaline Phosphatase), Monoclonal antibody, Clone: ALPP/238, Host: Mouse, Species reactivity: Human, Isotype: IgM, kappa, Conjugate: CF594, Immunogen: Recombinant full-length human ALPP protein, Application: IF, Immunohistology (formalin), Flow, Size: 500uL

Catalog Number: 75970-372

Supplier: Biotium

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Description: Probenecid is commonly used to inhibit organic-anion transporters located in the cell membrane. Such transporters can extrude dyes and indicators and thus contribute to low signal or high background in assays due to poor cellular retention of dyes. The use of probenecid to block the efflux of intracellular dyes was first described by Di Virgilio et al. (1990), and it has been used with a wide range of anionic dyes and conjugates.

Catalog Number: 89410-769

Supplier: Biotium

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Description: EGFr Monoclonal antibody, Clone: GFR1195, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Recom human EGFR protein, Synonyms: Erbb1, ERBB1, Errp, HER1, mENA, PIG61, Proto-oncogene c-ErbB-1, Application: IF, IHC, Size: 500uL

Catalog Number: 75925-504

Supplier: Biotium

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Description: The epitope of this MAb maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2 levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Catalog Number: 75972-876

Supplier: Biotium

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Description: Kappa Light Chain, Monoclonal antibody, Clone: Kap-56, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, BSA-free, Immunogen: Purified human Ig kappa chain (HP6053) & Human B-Lymphoma Cells (L1C1), Synonyms: Ig Kappa Chain C Region, Size: 50 uL

Catalog Number: 75955-564

Supplier: Biotium

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Description: Cytokeratin 8/18 Monoclonal antibody, Clone: B22.1 + B23.1, Host: Mouse, Species reactivity: Human, Isotype: IgG1, K, Conjugate: CF543, Immunogen: Cytoskeletal preparation from HeLa epitheliod carcinoma cells and PMC-42 breast carcinoma cells, Size: 100uL

Catalog Number: 75920-690

Supplier: Biotium

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Description: BCL-2 Monoclonal antibody, Clone: 100/D5, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: A synthetic peptide, aa41-54 of human BCL-2 protein, Synonyms: B-cell CLL/lymphoma-2, Application: IF, IHC, WB, FC, Size: 100uL

Catalog Number: 75884-592

Supplier: Biotium

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Description: Bax Monoclonal antibody, Clone: 2D2, Host: Mouse, Species Reactivity: Human, Monkey, Isotype: IgG1, Conjugate: CF405S, Immunogen: Recognizes a protein of 21kDa, identified as the Bax protein, Application: Immunofluorescence, Immunohistology, Wb, Fc, Size: 100ul

Catalog Number: 75886-004

Supplier: Biotium

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Description: This antibody recognizes an oncofetal glycoprotein with a single chain of 70 kDa, which is identified as alpha fetoprotein (AFP) (ISOBM TD-2 workshop). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Catalog Number: 75883-798

Supplier: Biotium

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