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Catalog Number: (89139-500)

Supplier: Biotium

Description: RuBP-4S ([Ruthenium(bathophenanthroline)(bis(bathophenanthrolinedisulfonate))],disodium salt) is a luminescent ruthenium complex similar to RuBPS (80021). Two of the bathophenanthroline ligands are bis-sulfonated while the third bathophenanthroline ligand is neutral, resulting in an overall double negative charges of the ruthenium complex.

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Supplier: Biotium

Description: Laminins are large hetero-trimeric, non-collagenous glycoproteins composed of α, β, and γ chains. This MAb reacts with laminin B2/1 chain of ~210 kDa and does not cross-react with other basement membrane components or fibronectin. Its specificity was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Epithelial sheets in vivo are separated from the mesenchymal elements of the stroma by a thin layer of a specialized type of extracellular matrix termed the basement membrane (BM). This structure consists of individual components, some of which are ubiquitous in BMs and some are not. The ubiquitous ones comprise laminin (LN), entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms. This MAb stains uniformly all human and murine basement membranes.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Supplier: Biotium

Description: Cytokeratin 18 Monoclonal antibody, Clone: C-04, Host: Mouse, Species reactivity: Hamster, Goat, Horse, Monkey, Pig, Dog, Cow, Cat, Sheep, Rat, Marmoset, Human, Ferret, Mouse, Isotype: IgG1, K, Conjugate: purified, Immunogen: cell line A431, Size: 100uL

Supplier: Biotium

Description: Insulin, Monoclonal antibody, Clone: E2-E3 + 2D11-H5, Host: Mouse, Species reactivity: Mouse, Pig, Cow, Human, Rabbit, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Purified pig insulin, conjugated to KLH, Synonyms: IDDM2, ILPR, IRDN, MODY10, Application: IF, Size: 100uL

Supplier: Biotium

Description: This antibody recognizes a protein of 30 kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.

Supplier: Biotium

Description: This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this MAb is mapped between aa120-170. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Supplier: Biotium

Description: Cytokeratin 7 Monoclonal antibody, Clone: K72.7, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF405S, Immunogen: Semi-purified cytokeratin preparation, Synonyms: CK-7, K2C7, Keratin 55K Type II, Application: IF, IHC, FC, Size: 500 uL

Supplier: Biotium

Description: This antibody recognizes a phosphor-protein of 45 kDa, identified as MyoD1. This MAb does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Supplier: Biotium

Description: Lambda Light Chain, Monoclonal antibody, Clone: LcN-2, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, kappa, Conjugate: purified, Immunogen: Purified IgG myeloma proteins coupled to polyaminostyren, Synonyms: BJP, Application: IF, Size: 100uL

Supplier: Biotium

Description: This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120 kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi's sarcoma, but with a lower specificity.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®555 is a bright orange-red fluorescent dye (Ex/Em 555/565 nm) that is compatible with super-resolution imaging by STORM.

Supplier: Biotium

Description: RedDot™1 is a far-red cell membrane-permeable nuclear dye similar to Draq5™. The dye is ideal for specifically staining the nuclei of live cells.

Supplier: Biotium

Description: Retinol Binding Protein-1, Monoclonal antibody, Clone: G4E4, Host: Mouse, Species reactivity: Goat, Chimpanzee, Monkey, Rat, Human, Rabbit, Isotype: IgG2a, kappa, Conjugate: purified, Immunogen: Retinol binding protein-1 purified from human plasma, Size: 100uL

Supplier: Biotium

Description: FOXP3 Monoclonal antibody, Clone: FXP3/197, Host: Mouse, Species reactivity: Mouse, Monkey, Human, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Recombinant human full-length FOXP3 protein, Application: IF, Immunohistology, Size: 500 uL

Catalog Number: (89427-060)

Supplier: Biotium

Description: Activated charcoal retains ethidium bromide, GelRed™ and GelGreen™ efficiently in a convenient bag for decontamination of used gel staining solutions. Each bag has a total capacity of at least 10 mg ethidium bromide.

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Supplier: Biotium

Description: MHC II (HLA-DRA), Monoclonal antibody, Clone: IPO-10, Host: Mouse, Species reactivity: Human, Monkey, Isotype: IgM, kappa, Conjugate: CF640R, Immunogen: Spleen cells of a patient with hairy cell leukemia (Daudi cells), Application: Immunofluorescence, Flow, Size: 100uL

Supplier: Biotium

Description: P24-HIV, Monoclonal antibody, Clone: p24/661, Host: Mouse, Species reactivity: HIV Type 1, Isotype: IgG2b, kappa, Conjugate: biotin, Immunogen: Recombinant HIV-1 Gag p24 protein, Synonyms: Capsid protein p24; Human immunodeficiency virus type 1 p24, Application: IHC, Size: 100uL