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Supplier: Biotium

Description: MHC II (HLA-DRA), Monoclonal antibody, Clone: 19-26.1, Host: Mouse, Species reactivity: Human, Monkey, Isotype: IgM, kappa, Conjugate: purified, Immunogen: Spleen cells of a patient with hairy cell leukemia (Daudi cells), Application: Immunofluorescence, Size: 500uL

Supplier: Biotium

Description: CD8 Monoclonal antibody, Clone: C8/468 + C8/144B, Host: Mouse, Species reactivity: Human, Isotype: IgG1, K, Conjugate: CF405S, Immunogen: A 13 amino acid synthetic peptide, C-term, Synonyms: T8/Leu-2, Application: IF, Size: 100uL

Supplier: Biotium

Description: Granulocyte Marker, Monoclonal antibody, Clone: BM-1, Host: Mouse, Species reactivity: Human, Isotype: IgG1, Conjugate: CF488A, Immunogen: Human peripheral blood mononuclear cells, Synonyms: Myeloid specific protein; p183 DNA-binding cytoplasmic protein, Size: 500uL

Supplier: Biotium

Description: Mucin 5AC (MUC5AC), Monoclonal antibody, Clone: 45M1, Host: Mouse, Species reactivity: Mouse, Hedgehog, Monkey, Pig, Cat, Rat, Human, Chicken, Rabbit, Isotype: IgG1, kappa, Conjugate: CF568, Synonyms: Apomucin Major Airway Glycoprotein, Size: 100uL

Supplier: Biotium

Description: Goat anti-mouse IgG2a is an affinity-purified antibody that reacts with Fc portion of the heavy chain of mouse IgG2a. To minimize cross reactivity, the antibody is cross-adsorbed against other mouse IgG subclasses (IgG1, IgG2b, IgG3), and human, bovine and rabbit serum proteins. CF™405S is a blue fluorescent dye with an absorption peak wavelength that nearly coincides with the 405 nm blue diode laser line. In addition, the emission peak wavelength of the dye well centers within the blue detection window of BD flow cytometers. As a result, flow cytometry analysis using CF™405S results in much brighter signal compared to Alexa Fluor® 405.

Alexa Fluor® is a registered trademark of Thermo Fisher Scientific.

Supplier: Biotium

Description: CD31 / PECAM-1 Monoclonal antibody, Clone: JC70/A + C31.3, Host: Mouse, Conjugate: CF405S, Species reactivity: Rabbit, Cynomolgus monkey, Human, Immunogen: Recom CD31 protein (C31.3), Isotype: IgG, Synonyms:EndoCAM, Application: IF, IHC, FC, Size: 500 uL

Supplier: Biotium

Description: This MAb recognizes a 60 kDa antigen associated with the mitochondria in human cells. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. It recognizes an antigen associated with the mitochondria in human cells only. It can be used to stain the mitochondria in cell or tissue preparations and can be used as a mitochondrial marker in subcellular fractions. It produces a spaghetti-like pattern in normal and malignant cells and may be used to stain mitochondria of cells in fixed or frozen tissue sections. It can also be used with paraformaldehyde fixed frozen tissue or cell preparations. This MAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells, including neurons and embryonic stem cells.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Catalog Number: (10119-228)

Supplier: Biotium

Description: Secondary, Host species: Goat; Reactivity (target): Mouse; Cross adsorption: bovine, horse, human, rabbit, swine; Size: 100 uL; Concentration: 1 mg/mL; HRP conjugates could be used for standard immunoassay applications.

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Supplier: Biotium

Description: Cytochrome c is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic Cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, Cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of Cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of Cytochrome c and to induce cell death. The release of Cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a Cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Supplier: Biotium

Description: Kappa Light Chain, Monoclonal antibody, Clone: HP6053, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Purified human Ig kappa chain (HP6053) & Human B-Lymphoma Cells (L1C1), Synonyms: Ig Kappa Chain C Region, Size: 500uL

Supplier: Biotium

Description: Von Willebrand Factor, Monoclonal antibody, Clone: VWF635, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Recombinant human vWF fragment spanning aa 845-949, Synonyms: Coagulation Factor VIII, Application: IF, Size: 500uL

Supplier: Biotium

Description: CD34 Monoclonal antibody, Clone: QBEnd/10, Host: Mouse, Species reactivity: Human, Rhesus monkey, Cynomolgus monkey, Isotype: IgG1, K, Conjugate: CF568, Immunogen: Detergent solubilized vesicular suspension prepared, Synonyms: HPCA1, Application: IF, Size: 500 uL

Supplier: Biotium

Description: Is a far red fluorescent dye optimally excited by 633/635 nm lasers, with superior photostability compared to AlexaFluor 647. CF633 is a direct replacement for Alexa Fluor633, Alexa Fluor647, Cy5 and DyLight 649.

Supplier: Biotium

Description: The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.

Supplier: Biotium

Description: This monoclonal antibody is part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This MAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells.,Double Stranded deoxyribonucleic acid (ds DNA) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds between complementary base pairs.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Supplier: Biotium