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Supplier: Enzo Life Sciences
Description: The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or ?executioner? caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

Catalog Number: (76284-790)
Supplier: Enzo Life Sciences
Description: Recombinant monclonal antibody (Rabbit IgGκ).

Recommended Applications: IF, IHC (FS), IHC (PS), IP, WB


Catalog Number: (76285-076)
Supplier: Enzo Life Sciences
Description: Recombinant monclonal antibody (Human IgG1κ).

Recommended Applications: Flow Cytometry, FUNC


Supplier: Enzo Life Sciences
Description: TCP-1 alpha is a 60 kDa subunit of a cytosolic hetero-oligomer chaperone that is known to be involved in the folding of Actin and Tubulin. This protein is a member of the Chaperonin family, which includes E. coli GroEL, the mitochondrial Heat-shock protein Hsp60, the plastid Rubisco-subunit-binding protein, and the archaebacterial protein TF55. These Chaperonins assist the folding of proteins upon ATP hydrolysis.

Supplier: Enzo Life Sciences
Description: The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

Supplier: Enzo Life Sciences
Description: Golgi SNARE of 28 kDa (GS28), also known as p28 or GOS28, is a 28 kDa integral membrane protein on the surface of the Golgi apparatus that serves as a t-SNARE in ER to Golgi transport. The amino-terminal of GS28 is exposed to the cytosol and is anchored to the cis Golgi via a 20 amino acid carboxyl-terminal hydrophobic tail. GS28 co-immunoprecipitates complexes consisting of Syntaxin 5, Rbet1, Membrin, Rsec22, and Rsly1, and is therefore implicated in ER to-Golgi or intra-Golgi vesicle transport.

Catalog Number: (76284-592)
Supplier: Enzo Life Sciences
Description: Recombinant monclonal antibody (Human Fab fragment κ).

Recommended Applications: Flow Cytometry, WB


Catalog Number: (76284-884)
Supplier: Enzo Life Sciences
Description: Recombinant monclonal antibody (Hamster (Armenian) IgGκ).

Recommended Applications: ELISA, WB


Catalog Number: (76201-918)
Supplier: Enzo Life Sciences
Description: Recombinant monoclonal antibody


Catalog Number: (10049-292)
Supplier: Enzo Life Sciences
Description: The fragmentation of nuclear DNA is a hallmark of apoptotic cell death. EndoG is a mitochondrion specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis in a caspase independent fashion.


Supplier: Enzo Life Sciences
Description: Produced in <i>E. coli.</i> Contains 116/232 amino acids.

Catalog Number: (76201-866)
Supplier: Enzo Life Sciences
Description: Recombinant monoclonal antibody


Catalog Number: (76284-718)
Supplier: Enzo Life Sciences
Description: Recombinant monclonal antibody (Human IgG2λ).

Recommended Applications: Flow Cytometry, WB


Supplier: Enzo Life Sciences
Description: GDF-5 human Recombinant, Purity: >/=98%, Source: Produced in E. Coli. Non-glycosylated homodimer, Synonyms: GDF-5, CDMP-1, BMP-14, Bone morphogenetic protein 14, Cartilage-derived morphogenetic protein 1, Appearance: White lyophilized, size: 10 ug

Catalog Number: (76271-436)
Supplier: Enzo Life Sciences
Description: Recombinant monoclonal antibody (Rabbit IgG).

Recommended Applications: IHC (PS), WB


Catalog Number: (76284-600)
Supplier: Enzo Life Sciences
Description: Recombinant monclonal antibody (Human IgG1κ).

Recommended Applications: Flow Cytometry, WB


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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