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Product Image-95057-940

Anti-HSP25 Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: G3.1]

Supplier: Enzo Life Sciences
Description: Hsp27 is one of the most common members of the highly conserved and ubiquitously expressed family of small heat shock proteins (sHsp), which also includes alphaB-crystallin. It is characterized by a conserved C-terminal alpha-crystallin domain consisting of two anti-parallel beta-sheets that promote oligomer formation required for its primary chaperone function as inhibitor of irreversible protein aggregation. Hsp27 oligomerization is modulated by post-translational phosphorylation of Hsp27 at three serine residues, Ser15, Ser78, and Ser82, by a variety of protein kinases including MAPKAPK-3, PKAc-alpha, p70 S6K, PKD I, and PKC-delta. Hsp27 has been shown to inhibit actin polymerization by binding of unphosphorylated Hsp27 monomers to actin intermediate filaments. Anti-apoptotic functions of Hsp27 have also been identified through interactions with DAXX7, activation of Akt, and inhibition of apoptosome formation. Evidence suggests altered expression of Hsp27 is implicated in the pathogenesis of breast, ovarian, and prostate cancer.

SDS

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Anti-FLG Rabbit Polyclonal Antibody

Catalog Number: (76002-722)
Supplier: Enzo Life Sciences
Description: Recommended Applications: IF, IHC, WB

Species reactivity: Human, Mouse, Primate
Image Unavailable-76288-376

Human Recombinant Granulocyte-Colony Stimulating Factor

Supplier: Enzo Life Sciences
Description: Produced in <i>E. coli.</i> A monomer containing 175 amino acids.

Product Image-200061-460

Anti-GST Mouse Monoclonal Antibody

Catalog Number: (200061-460)
Supplier: Enzo Life Sciences
Description: The GST superfamily of enzymes play an important role in detoxification of xenobiotics by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. There are four main GST classes; alpha, mu, pi, and tau. GST-P is a member of the pi class of GSTs, and its expression is specifically increased in the early stages of rat hepatocarcinogenesis. Due to its high affinity for glutathione, GST is frequently utilized as an approximately 26 kDa fusion tag for the expression and purification of recombinant proteins.
Product Image-10049-828

Anti-AGRN Mouse Monoclonal Antibody [clone: Agr-33]

Catalog Number: (10049-828)
Supplier: Enzo Life Sciences
Description: Monoclonal Antibody, Primary Antibody, Used in ICC, IHC with species reactivity to Mouse, Rat, Host: Mouse, Immunogen: Recombinant rat agrin (C-terminal fragment), Isotype: IgG1
Image Unavailable-76203-504

Alectinib hydrochloride ≥99% (by HPLC)

Supplier: Enzo Life Sciences
Description: Alectinib hydrochloride is a selective anaplastic lymphoma kinase (ALK) inhibitor leading to inhibition of tumor cell proliferation and induction of cell death. 

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Dacomitinib free base ≥99% (by HPLC)

Supplier: Enzo Life Sciences
Description: Dacomitinib is a potent, highly selective, second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor (EGFR) family of tyrosine kinases (ErbB family) with potential antineoplastic activity.

Product Image-10049-856

Anti-HMGB1 Mouse Monoclonal Antibody [clone: KS1]

Catalog Number: (10049-856)
Supplier: Enzo Life Sciences
Description: The chromatin non-histone high mobility group of proteins (HMG)-1 and -2 contain conserved domains known as HMG-boxes. Both HMG-1 and HMG-2 contain an N-terminal HMG box, a central HMG box and an acidic carboxy terminus. HMG-1/2 have been shown to facilitate the binding of various sequence-specific transcription factors to their respective DNA binding sites, such as steroid hormone receptors, and p53.
Image Unavailable-76002-700

Anti-GST Rabbit Polyclonal Antibody

Catalog Number: (76002-700)
Supplier: Enzo Life Sciences
Description: Recommended Applications: WB

Species reactivity:
Image Unavailable-76203-628

Mouse Recombinant IL-5 (from E. coli)

Supplier: Enzo Life Sciences
Description: Produced in <i>E. coli.</i> Contains 113/226 amino acids.

Image Unavailable-75786-328

LH ELISA Kit, Enzo Life Sciences

Catalog Number: (75786-328)
Supplier: Enzo Life Sciences
Description: Highly sensitive LH ELISA kit enabling detection of LH in serum, plasma and tissue culture media in just 2 hours.

SDS


Product Image-95045-930

Anti-PKC alpha Mouse Monoclonal Antibody

Supplier: Enzo Life Sciences
Description: Protein Kinase C (PKC) is a large superfamily of serine/threonine kinases that mediate essential cellular signals required for activation, proliferation, differentiation and survival. There are at least ten PKC isotypes that are closely related in structure but that have distinct patterns of tissue distribution and function. The PKC isotypes can be subdivided into three classes based on primary structure and biochemical properties. These are: classical or conventional PKC isotypes (cPKC), novel PKC isotypes (nPKC) and atypical PKC isotypes (aPKC).

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N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride ≥95% (by HPLC)

Supplier: Enzo Life Sciences
Description: EGFR tyrosine kinase auto-phosphorylation inhibitor

Product Image-10049-896

Anti-IDO1 Mouse Monoclonal Antibody [clone: 200]

Catalog Number: (10049-896)
Supplier: Enzo Life Sciences
Description: Indoleamine 2,3-dioxygenase (IDO) is an IFN-γ inducible gene. It catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine. IDO has been implicated to protect against intracellular and extracellular pathogens. . IDO1 is also known as Indolamine 2,3-dioxygenase, Indole 2,3-dioxygenase, and Indoleamine-pyrrole 2,3-dioxygenase. IDO is a ubiquitously expressed cytoplasmic protein with a predicted molecular weight of approximately 45 kDa. Indoleamine 2,3-dioxygenase (IDO) is one the best known IFN-γ inducible genes. The product of IDO gene catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine. IDO has been implicated to protect against intracellular and extracellular pathogens. It also has been shown to maintain the special immune suppressive status of immune-privileged sites such as the brain, eyes, kidney, and placenta.
Product Image-10050-140

Anti-DJ-1 Mouse Monoclonal Antibody [clone: 3E8]

Catalog Number: (10050-140)
Supplier: Enzo Life Sciences
Description: Researchers cloned DJ-1 protein, consisting of 189 amino acids, from a HeLa cell cDNA library as a oncogene which weakly transformed NIH3T3 cells. Cotransfection with ras or c-myc enhances transformation by DJ-11. DJ-1 expression is induced by growth signals, and it is translocated from the cytoplasm to the nucleus during the S phase without the presence of any nuclear localization signals. In addition to its potential involvement in ras-mediated signal transduction pathways, DJ-1 is known to regulate transcription of androgen-responsive genes, and is sensitive to oxidative stress. DJ-1 is ubiquitously expressed in various human tissues including the brain, with high expression in astrocytes of the frontal cortex and substantia nigra. Homozygous mutations in the DJ-1 gene have been shown to cause early-onset autosomal recessive Parkinson’s disease.
Image Unavailable-76284-740

Anti-C3AR1 Mouse Monoclonal Antibody [clone: 3G8]

Catalog Number: (76284-740)
Supplier: Enzo Life Sciences
Description: Recombinant monclonal antibody (Mouse IgGκ).

Recommended Applications: ELISA, Flow Cytometry
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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* Please note if your account is within the State of California two of these pieces of identification will be required.
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