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Catalog Number: (10371-174)
Supplier: Bioss
Description: Siah2 is a E3 Ubiquitin ligase protein that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targets. Siah2 triggers the ubiquitin-mediated degradation of many proteins, including transcription regulators (e.g. POU2AF1, PML, NCOR1), cell surface receptors (e.g. DCC), antiapoptotic proteins (e.g. BAG1), and proteins involved in synaptic vesicle function in neurons (e.g. SYP). Siah2 has some overlapping function with SIAH1 but is able to trigger the ubiquitin-mediated degradation of TRAF2, whereas SIAH1 can not.


Catalog Number: (10406-972)
Supplier: Bioss
Description: Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.


Catalog Number: (10107-310)
Supplier: Prosci
Description: SMAD2 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. SMAD2 mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. SMAD2 is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, SMAD2 is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin.The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants encoding the same protein have been observed.


Catalog Number: (89521-404)
Supplier: Abgent
Description: Western Blot: 1:1000


Catalog Number: (10112-114)
Supplier: Prosci
Description: Polyclonal, Host: Goat, Species: Human, Immunogen: STAG3 antibody was raised against a 12 amino acid synthetic peptide near the internal region of STAG3, Application: ELISA


Catalog Number: (10667-292)
Supplier: Bioss
Description: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.


Catalog Number: (10206-938)
Supplier: Boster Biological Technology
Description: Rabbit IgG polyclonal antibody for Mothers against decapentaplegic homolog 2(SMAD2) detection. Tested with WB, IHC-P, ICC in Human;Mouse;Rat.


Catalog Number: (10719-814)
Supplier: Abnova
Description: Mouse monoclonal antibody raised against native ITGB2.


Catalog Number: (10735-644)
Supplier: Abnova
Description: Mouse monoclonal antibody raised against synthetic peptide of SIAH2.


Catalog Number: (10719-802)
Supplier: Abnova
Description: Mouse monoclonal antibody raised against recombinant ITGB2.


Catalog Number: (10094-852)
Supplier: Proteintech
Description: Anti-SMAP2 Antibody, Host Species: Rabbit, Cross Reactivity: Human,Mouse,Rat, Immunogen: Recombinant Protein, 77-429 amino acid, Format:Antigen affinity purification, Application: ELISA, WB, IHC, IF, Recommended Storage: - 20 C or lower


Catalog Number: (10732-338)
Supplier: Abnova
Description: Rabbit polyclonal antibody raised against synthetic peptide of Scarb2.


Catalog Number: (10719-810)
Supplier: Abnova
Description: Mouse monoclonal antibody raised against native ITGB2.


Catalog Number: (76699-614)
Supplier: AFG BIOSCIENCE LLC
Description: Human Heat Stable Antigen (HSA/CD24) ELISA Kit


Catalog Number: (77704-948)
Supplier: AFG BIOSCIENCE LLC
Description: WB:1:500-1:2000, IHC:1:100-1:300, ELISA:1:10000

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Supplier: THERMO FISHER SCIENTIFIC CHEMICALS
Description: Hydrogen peroxide 3% (w/w) in water stabilized

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