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Catalog Number: (10169-020)
Supplier: Genetex
Description: Mouse monoclonal antibody [4G4] to Raf1


Catalog Number: (10578-060)
Supplier: Abnova
Description: BRAF monoclonal antibody (M03), clone 2E9, Mouse monoclonal antibody raised against a partial recombinant BRAF, Size: 100ug


Catalog Number: (10623-858)
Supplier: Abnova
Description: Mouse monoclonal antibody raised against a full-length recombinant BRF1.


Catalog Number: (220020-446)
Supplier: R&D Systems
Description: Anti-BRAF Mouse Monoclonal Antibody [clone: 336016]


Catalog Number: (10691-468)
Supplier: Abnova
Description: Mouse monoclonal antibody raised against recombinant BRAF.


Catalog Number: (89360-856)
Supplier: Genetex
Description: The Raf kinases are important inter-mediates in signal transduction. Raf-l proteins have intrinsic serine/threonine kinase activity. Interaction between Ras proteins and Raf proteins results in Raf-mediated phosphorylation and activation of MEK (also known as MAP kinase kinase).


Catalog Number: (ABCA_AB308176-100U)
Supplier: ABCAM INC.
Description: Anti-BRAF Rabbit Monoclonal Antibody [clone: HL1606]

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Catalog Number: (10578-068)
Supplier: Abnova
Description: BRAF monoclonal antibody (M07), clone 1F2, Mouse monoclonal antibody raised against a partial recombinant BRAF, Size: 100ug


Catalog Number: (10551-568)
Supplier: Abnova
Description: BRAF monoclonal antibody (M01), clone 3C6, Mouse monoclonal antibody raised against a partial recombinant BRAF, Size: 50ug


Catalog Number: (10578-072)
Supplier: Abnova
Description: BRAF monoclonal antibody (M09), clone 4F4, Mouse monoclonal antibody raised against a partial recombinant BRAF, Size: 100ug


Catalog Number: (10623-758)
Supplier: Abnova
Description: BRAF monoclonal antibody (M01A), clone 3C6, Mouse monoclonal antibody raised against a partial recombinant BRAF, Size: 200ul


Catalog Number: (10599-084)
Supplier: Abnova
Description: RAF1 monoclonal antibody (M03), clone 1H4, Mouse monoclonal antibody raised against a partial recombinant RAF1, Size: 100ug


Catalog Number: (10578-064)
Supplier: Abnova
Description: BRAF monoclonal antibody (M05), clone 4G7, Mouse monoclonal antibody raised against a partial recombinant BRAF, Size: 100ug


Catalog Number: (10578-062)
Supplier: Abnova
Description: BRAF monoclonal antibody (M04), clone 2F7, Mouse monoclonal antibody raised against a partial recombinant BRAF, Size: 100ug


Supplier: DIACARTA
Description: DiaCarta's QClamp® BRAF Codon Specific Mutation Detection kit is a polymerase chain reaction (PCR)-based assay that uses XNA probes to suppress amplification of WT-DNA, selectively amplifying mutant DNAs

Catalog Number: (76100-794)
Supplier: Bioss
Description: Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, survival and oncogenic transformation. RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kinases (MAPK3/ERK1 and MAPK1/ERK2). The phosphorylated form of RAF1 (on residues Ser-338 and Ser-339, by PAK1) phosphorylates BAD/Bcl2-antagonist of cell death at 'Ser-75'. Phosphorylates adenylyl cyclases: ADCY2, ADCY5 and ADCY6, resulting in their activation. Phosphorylates PPP1R12A resulting in inhibition of the phosphatase activity. Phosphorylates TNNT2/cardiac muscle troponin T. Can promote NF-kB activation and inhibit signal transducers involved in motility (ROCK2), apoptosis (MAP3K5/ASK1 and STK3/MST2), proliferation and angiogenesis (RB1). Can protect cells from apoptosis also by translocating to the mitochondria where it binds BCL2 and displaces BAD/Bcl2-antagonist of cell death. Regulates Rho signaling and migration, and is required for normal wound healing. Plays a role in the oncogenic transformation of epithelial cells via repression of the TJ protein, occludin (OCLN) by inducing the up-regulation of a transcriptional repressor SNAI2/SLUG, which induces down-regulation of OCLN. Restricts caspase activation in response to selected stimuli, notably Fas stimulation, pathogen-mediated macrophage apoptosis, and erythroid differentiation.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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