You Searched For: bra30

Catalog Number: (103521-250)

Supplier: IXCELLS BIOTECHNOLOGIES USA MS

Description: Rat Astrocytes (RA); Frozen

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Catalog Number: (10261-226)

Supplier: Bioss

Description: The homeobox is DNA sequence that is approximately 180 base pairs long that is involved in all steps of the developmental regulation of animals, fungi and plants, from embryogenesis to cell differentiation. The homeobox encodes a protein domain of about 60 amino acids, called the homeodomain, that can bind to DNA. The gastrulation brain homeobox 1 (GBX1) gene, along with another homeobox gene (EN2), maps to chromosome 7q36, and is expressed in septal and pallidal areas and in the basal forebrain cholinergic system, an area implicated in Alzheimer’s disease. The GBX1 gene encodes the GBX1 protein, which localizes to the nucleus and contains 1 homeobox DNA-binding domain.

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Supplier: Biotium

Description: S100, Monoclonal antibody, Clone: 4C4.9, Host: Mouse, Species reactivity: Mouse, Cow, Rat, Human, Isotype: IgG2a, kappa, Conjugate: biotin, Immunogen: Purified bovine brain S100 protein, Synonyms: Bpb; NEF; S100-A1; S100 Alpha Chain, Application: IF, IHC Western, Size: 500uL

Catalog Number: (10267-488)

Supplier: Bioss

Description: NETO2 is a 525 amino acid single-pass type I membrane protein that contains two CUB domains and one LDL-receptor class A domain. Expressed as multiple alternatively spliced isoforms, NETO2 is thought to play a role in the development and maintenance of neuronal circuitry, possibly playing a role in proper brain function. The gene encoding NETO2 maps to human chromosome 16, which is associated with a variety of genetic disorders, encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

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Supplier: Biotium

Description: S100, Monoclonal antibody, Clone: 4C4.9, Host: Mouse, Species reactivity: Mouse, Cow, Rat, Human, Isotype: IgG2a, kappa, Conjugate: CF488A, Immunogen: Purified bovine brain S100 protein, Synonyms: Bpb; NEF; S100-A1; S100 Alpha Chain, Application: IF, IHC Western, Size: 500uL

Supplier: Biotium

Description: S100, Monoclonal antibody, Clone: 4C4.9, Host: Mouse, Species reactivity: Mouse, Cow, Rat, Human, Isotype: IgG2a, kappa, Conjugate: CF555, Immunogen: Purified bovine brain S100 protein, Synonyms: Bpb; NEF; S100-A1; S100 Alpha Chain, Application: IF, IHC Western, Size: 500uL

Supplier: Biotium

Description: S100, Monoclonal antibody, Clone: 4C4.9, Host: Mouse, Species reactivity: Mouse, Cow, Rat, Human, Isotype: IgG2a, kappa, Conjugate: CF647, Immunogen: Purified bovine brain S100 protein, Synonyms: Bpb; NEF; S100-A1; S100 Alpha Chain, Application: IF, IHC Western, Size: 100uL

Catalog Number: (103287-714)

Supplier: Novus Biologicals

Description: The BEX5 Antibody from Novus Biologicals is a rabbit polyclonal antibody to BEX5. This antibody reacts with human. The BEX5 Antibody has been validated for the following applications: Immunohistochemistry, Immunohistochemistry-Paraffin.

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Catalog Number: (10251-144)

Supplier: Bioss

Description: Dbx1 homeodomain transcription factor is expressed in progenitors at the boundary between the dorsal and ventral plates of the caudal neural tube, from which postmitotic cells migrate tangentially to their final destination. Dbx1 is implicated in patterning the central nervous system during embryogenesis. Cell fate allocation and cell diversity are determined at very early stages in progenitor cells at precise coordinates along the dorsoventral and anteroposterior axis. In the spinal cord, the spatially restricted expression of Dbx1 in progenitors is critical in establishing interneuron cell fates and helps coordinate diverse phenotypic features. In the telencephalon, Dbx1 is expressed in restricted progenitor domains at the borders of the developing pallium.

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Supplier: Biotium

Description: S100, Monoclonal antibody, Clone: 4C4.9 + S100A1/1012, Host: Mouse, Species reactivity: Mouse, Cow, Rat, Human, Isotype: IgG2a, kappa, Conjugate: biotin, Immunogen: Purified bovine brain S100 protein, Synonyms: Bpb; NEF; S100-A1; S100 Alpha Chain, Application: IF, Size: 100uL

Catalog Number: (89415-824)

Supplier: Prosci

Description: Rheb Antibody: Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure. While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor stimulation. Similar to other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway. Biochemical and genetic studies demonstrate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway. TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with protein translation and cell growth. A dimeric protein complex termed TSC1/TSC2 indirectly inhibits TOR activity by inhibiting Rheb via the GAP activity of TSC2.

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Catalog Number: (10801-462)

Supplier: Rockland Immunochemical

Description: FOXG1 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain and plays an important role in the development of the brain and telencephalon (1). It is essential for the proliferation of progenitor cells in the cerebral cortex and influences regional patterning in the mammalian telencephalon (2,3). Expression is restricted to the neurons of the developing telencephalon (3). The loss of FOXG1 results in an accelerated rate of neuronal differentiation and the shortening of the neurogenetic period in the embryonic cerebral cortex (2,4).

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Catalog Number: (10488-128)

Supplier: Bioss

Description: Glycolysis is an evolutionarily conserved series of ten chemical reactions that utilizes eleven enzymes to concomitantly generate pyruvate and ATP from glucose. fructose kinase-2/fructose 2,6-bisphosphatase (PFK-2) stimulates the synthesis and degradation of fructose 2,6-bisphosphate. Glycogen phosphorylase (also known as GP) is an allosteric enzyme important in carbohydrate metabolism. Its activity is regulated through either noncovalent binding of metabolites or by covalent modification. Glycogen phosphorylase catalyzes the phosphorylation of glycogen to Glc-1-P. There are three genes which encode the brain, liver and muscle forms of glycogen phosphorylase, PYGB, PYGL and PYGM. Because of its fundamental role in the metabolism of glycogen, glycogen phosphorylase has been a target for the design of inhibitory compounds, which could be valuable in the therapeutic treatment of type 2 diabetes mellitus.

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Supplier: Biotium

Description: S100, Monoclonal antibody, Clone: 4C4.9 + S100A1/1012, Host: Mouse, Species reactivity: Mouse, Cow, Rat, Human, Isotype: IgG2a, kappa, Conjugate: CF640R, Immunogen: Purified bovine brain S100 protein, Synonyms: Bpb; NEF; S100-A1; S100 Alpha Chain, Application: IF, Size: 500uL

Catalog Number: (10264-630)

Supplier: Bioss

Description: The isthmic organizer signals at the mid/hindbrain boundary (MHB) regulate the development and differentiation of the vertebrate caudal midbrain and the anterior hindbrain. The MHB forms at the boundary of expression between homeobox genes Gbx2 and Otx2. Gbx2 and Otx2 play distinct, essential roles in MHB positioning and development. During development, the GBX2 gene is expressed in the anterior hindbrain. Specifically, Gbx2 negatively regulates Otx2 expression along the anterior-posterior axis; Gbx2(-) mutants demonstrate an expanded Otx2 domain. During development, the GBX2 gene is expressed in the anterior hindbrain. Gbx2 is expressed in the adult brain, spleen and female genital tract. The GBX2 gene is over-expressed in human prostate cancer cell lines (TSU-prl, PC3, DU145 and LNCaP). Furthermore, downregulation of Gbx2 expression restricts tumorigenicity in human prostate cancer cell lines, which suggests that Gbx2 expression may be required for growth of malignant prostate cells.

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Catalog Number: (10261-222)

Supplier: Bioss

Description: The homeobox is DNA sequence that is approximately 180 base pairs long that is involved in all steps of the developmental regulation of animals, fungi and plants, from embryogenesis to cell differentiation. The homeobox encodes a protein domain of about 60 amino acids, called the homeodomain, that can bind to DNA. The gastrulation brain homeobox 1 (GBX1) gene, along with another homeobox gene (EN2), maps to chromosome 7q36, and is expressed in septal and pallidal areas and in the basal forebrain cholinergic system, an area implicated in Alzheimer’s disease. The GBX1 gene encodes the GBX1 protein, which localizes to the nucleus and contains 1 homeobox DNA-binding domain.

Sale