You Searched For: Fmoc-5-methyl-DL-tryptophan


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Catalog Number: (10232-652)
Supplier: Bioss
Description: Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.


Catalog Number: (76994-308)
Supplier: GeminiBio
Description: This diagnostic-grade product is an aqueous solution containing 25% human albumin (w/v). It is prepared by cold-alcohol fractionation from pooled human plasma obtained from venous blood. The USP Pharmacopeia requires that all fractionators add sodium caprylate and sodium tryptophanate as a preservative.


Catalog Number: (10104-566)
Supplier: Prosci
Description: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.


Catalog Number: (89304-890)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to 14-3-3 zeta


Catalog Number: (103612-876)
Supplier: Sino Biological
Description: Tryptophan Hydroxylase 1 / TPH1 Protein (His Tag) Recombinant, Purity: > 95 % as determined by SDS-PAGE, Host: E. Coli, Species: Human, Immunogen: The recom human TPH1 consisting of 458 amino acids and has a calculated molecular mass of 52.7 kDa, size: 50 ug


Catalog Number: (10105-800)
Supplier: Prosci
Description: Tryptophan hydroxylase (TPH; EC 1.14.16.4) is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility.


Catalog Number: (76110-986)
Supplier: Bioss
Description: 14-3-3 are activates tyrosine and tryptophan hydroxylases in the presence of Ca²⁺/calmodulin-dependent protein kinase II, and strongly activates protein kinase C. Is probably a multifunctional regulator of the cell signaling processes mediated by both kinases. Activates the ADP-ribosyltransferase (exoS) activity of bacterial origin. 14-3-3 proteins are localized in neurons, and are axonally transported to the nerve terminals. They may be also present, at lower levels, in various other eukaryotic tissues. It belongs to the 14-3-3 family.


Catalog Number: (10232-144)
Supplier: Bioss
Description: GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.


Catalog Number: (75793-322)
Supplier: Prosci
Description: IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.


Catalog Number: (10232-660)
Supplier: Bioss
Description: Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.


Catalog Number: (103007-804)
Supplier: Anaspec Inc
Description: This peptide is Exendin-4 labeled with fluorescein at the Tryptophan residue. FLEX is equipotent to GLP-1(7-36)-amide and exendin-4 as an inhibitor of [125I] GLP-1 binding to the human GLP-1 receptor stably expressed in CHO cells, and maintains full biological potency and efficacy as measured by the stimulation of cAMP accumulation in these cells. FLEX binding to CHO/hGLP-1R membranes results in an increase in fluorescence anisotropy. The binding is specific and saturable (Kd = 2.0 +/- 0.4 nM), and GLP-1(7-36)-amide and Exendin-4 are equipotent inhibitors of FLEX binding to the human GLP-1 receptor. Thus, FLEX is a potent, biologically active ligand that is useful for the study of the binding and functional characteristics of the human GLP-1 receptor.
Sequence: HGEGTFTSDLSKQMEEEAVRLFIE-(Trp-S-FAM)-LKNGGPSSGAPPPS-NH2
MW: 4606.4 Da
% Peak area by HPLC: 95
Storage condition: -20° C


Catalog Number: (77438-684)
Supplier: Bioss
Description: This gene encodes a protein that associates with the enzyme phosphoribosylpyrophosphate synthetase (PRS). PRS catalyzes the formation of phosphoribosylpyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, histidine, tryptophan and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits. This gene encodes a non-catalytic associated subunit of PRS. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011].


Catalog Number: (89276-904)
Supplier: Genetex
Description: Rabbit polyclonal antibody to 14-3-3 zeta (phospho S58)


Catalog Number: (76100-822)
Supplier: Bioss
Description: This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15 to p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.


Catalog Number: (89160-974)
Supplier: Enzo Life Sciences
Description: Fluorogenic substrate for several matrix metalloproteinases (MMPs). It is cleaved by MMP-1 (kcat/Km=3.3x10M-1s-1), MMP-2 (kcat/Km=5.8x10), MMP-3 (kcat/Km=2.2x10), MMP-7 (kcat/Km=1.2x10), MMP-8, MMP-9 (kcat/Km=6.9x10), and MMP-26 (kcat/Km=4.9x10) Ex/Em=280nm/346nm, although 283/350,360 are also appropriate. Fluorescence at 346 nm by tryptophan occurs once cleavage separates it from the quenching aromatic Dnp moiety. MMPs cleave this peptide between Gly-Leu.


Catalog Number: (77438-152)
Supplier: Bioss
Description: This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Jul 2008]


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